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Extract from the Register of European Patents

EP About this file: EP1648914

EP1648914 - OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN MODULATION OF SMALL NON-CODING RNAS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  06.09.2019
Database last updated on 24.04.2024
FormerExamination is in progress
Status updated on  02.10.2017
Most recent event   Tooltip06.09.2019Application deemed to be withdrawnpublished on 09.10.2019  [2019/41]
Applicant(s)For all designated states
Regulus Therapeutics Inc.
10614 Science Center Drive
San Diego, CA 92121 / US
[2016/29]
Former [2009/17]For all designated states
Regulus Therapeutics, Inc
1896 Rutherford Road
Carlsbad, CA 92008 / US
Former [2009/11]For all designated states
Regulus Therapeutics, LLC
1896 Rutherford Road
Carlsbad, CA 92008 / US
Former [2006/17]For all designated states
ISIS PHARMACEUTICALS, INC.
1896 Rutherford Road
Carlsbad, CA 92008 / US
Inventor(s)01 / ESAU, Christine
8726 Villa La Jolla Dr. 79
La Jolla, CA 92037 / US
02 / LOLLO, Bridget
2132 Pleasant Grove Road
Encinitas, CA 92024 / US
03 / BENNETT, C., Frank
1347 Cassins Street
Carlsbad, CA 92009 / US
04 / FREIER, Susan, M.
2946 Renault Street
San Diego, CA 92122 / US
05 / GRIFFEY, Richard, H.
360 Barsby Street
Vista, CA 92084 / US
06 / BAKER, Brenda, F.
2927 Ranchos Cortes
Carlsbad, CA 92009 / US
07 / VICKERS, Timothy
3326 Golfers Drive
Oceanside, CA 92056 / US
08 / MARCUSSON, Eric, G.
260 King Street 727
San Fransisco California 94017 / US
09 / KOLLER, Erich
2622 Lewis Lane
Carlsbad, CA 92009 / US
10 / SWAYZE, Eric, E.
7789 Palenque Street
Carlsbad, CA 92009 / US
11 / JAIN, Ravi
37896 Abraham Street
Fremont, CA 94536 / US
12 / BHAT, Balkrishen
911 Rosemary Avenue
Carlsbad, CA 92009 / US
13 / PERALTA, Eigen
810 Calle Lagasca
Chula Vista, CA 91910 / US
 [2007/21]
Former [2006/17]01 / ESAU, Christine
8726 Villa La Jolla Dr. 79
La Jolla, CA 92037 / US
02 / LOLLO, Bridget
2132 Pleasant Grove Road
Encinitas, CA 92024 / US
03 / BENNETT, C., Frank
1347 Cassins Street
Carlsbad, CA 92009 / US
04 / FREIER, Susan, M.
2946 Renault Street
San Diego, CA 92122 / US
05 / GRIFFEY, Richard, H.
360 Barsby Street
Vista, CA 92084 / US
06 / BAKER, Brenda, F.
2927 Ranchos Cortes
Carlsbad, CA 92009 / US
07 / VICKERS, Timothy
3326 Golfers Drive
Oceanside, CA 92056 / US
08 / MARCUSSON, Eric, G.
260 King Street 727
San Fransisco California 94017 / US
09 / KOLLER, Erich
2622 Lewis Lane
Carlsbad, CA 92009 / US
10 / SWAYZE, Eric, E.
7789 Palenque Street
Carlsbad, CA 92009 / US
11 / JAIN, Ravi
306 Chinquapin Avenue 2
Carlsbad, CA 92008 / US
12 / BHAT, Balkrishen
911 Rosemary Avenue
Carlsbad, CA 92009 / US
13 / PERALTA, Eigen
810 Calle Lagasca
Chula Vista, CA 91910 / US
Representative(s)Chapman, Desmond Mark, et al
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [2008/22]Hallybone, Huw George, et al
Carpmaels & Ransford 43-45 Bloomsbury Square
London WC1A 2RA / GB
Former [2006/17]Bassil, Nicholas Charles, et al
Kilburn & Strode 20 Red Lion Street
London WC1R 4PJ / GB
Application number, filing date04780181.630.07.2004
[2006/17]
WO2004US25300
Priority number, dateUS20030492056P31.07.2003         Original published format: US 492056 P
US20030516303P31.10.2003         Original published format: US 516303 P
US20030531596P19.12.2003         Original published format: US 531596 P
US20040562417P14.04.2004         Original published format: US 562417 P
[2006/17]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2005013901
Date:17.02.2005
Language:EN
[2005/07]
Type: A2 Application without search report 
No.:EP1648914
Date:26.04.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 17.02.2005 takes the place of the publication of the European patent application.
[2006/17]
Search report(s)International search report - published on:US02.03.2006
(Supplementary) European search report - dispatched on:EP12.11.2009
ClassificationIPC:C07H21/04, A61K48/00
[2006/17]
CPC:
C12N15/113 (EP,US); A61P3/00 (EP); A61P37/00 (EP);
C12N15/111 (EP,US); C12N2310/11 (US); C12N2310/113 (EP,US);
C12N2310/14 (EP,US); C12N2310/141 (US); C12N2310/31 (US);
C12N2310/315 (EP,US); C12N2310/317 (EP,US); C12N2310/3181 (EP,US);
C12N2310/32 (US); C12N2310/321 (EP,US); C12N2310/3231 (EP,US);
C12N2310/3341 (EP,US); C12N2310/341 (EP,US); C12N2310/346 (EP,US);
C12N2310/351 (US); C12N2310/3515 (US); C12N2320/11 (EP,US);
C12N2320/30 (US); C12N2320/50 (EP,US) (-)
C-Set:
C12N2310/321, C12N2310/3525 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/17]
Extension statesALNot yet paid
HRNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:OLIGOMERE VERBINDUNGEN UND ZUSAMMENSETZUNGEN ZUR VERWENDUNG BEI DER MODULIERUNG VON KLEINEN NICHT-KODIENDEREN RNAS[2006/17]
English:OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN MODULATION OF SMALL NON-CODING RNAS[2006/17]
French:COMPOSES OLIGOMERES ET COMPOSITIONS UTILISABLES POUR MODULER DES PETITS ARN NON-CODANTS[2006/17]
Entry into regional phase02.02.2006National basic fee paid 
02.02.2006Search fee paid 
02.02.2006Designation fee(s) paid 
02.02.2006Examination fee paid 
Examination procedure02.02.2006Amendment by applicant (claims and/or description)
02.02.2006Examination requested  [2006/17]
11.06.2010Despatch of a communication from the examining division (Time limit: M06)
21.12.2010Reply to a communication from the examining division
27.12.2011Despatch of a communication from the examining division (Time limit: M06)
24.10.2012Reply to a communication from the examining division
27.06.2013Observations by third parties
25.06.2014Despatch of a communication from the examining division (Time limit: M06)
09.04.2015Reply to a communication from the examining division
21.09.2017Despatch of a communication from the examining division (Time limit: M06)
17.07.2018Reply to a communication from the examining division
04.10.2018Despatch of a communication from the examining division (Time limit: M06)
16.04.2019Application deemed to be withdrawn, date of legal effect  [2019/41]
16.05.2019Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2019/41]
Divisional application(s)EP12173039.4  / EP2530157
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  11.06.2010
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
17.07.2018Request for further processing filed
17.07.2018Full payment received (date of receipt of payment)
Request granted
27.07.2018Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
09.04.2015Request for further processing filed
09.04.2015Full payment received (date of receipt of payment)
Request granted
21.09.2017Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
24.10.2012Request for further processing filed
24.10.2012Full payment received (date of receipt of payment)
Request granted
15.11.2012Decision despatched
Fees paidRenewal fee
02.02.2006Renewal fee patent year 03
04.07.2007Renewal fee patent year 04
10.07.2008Renewal fee patent year 05
16.07.2009Renewal fee patent year 06
26.07.2010Renewal fee patent year 07
07.07.2011Renewal fee patent year 08
25.07.2012Renewal fee patent year 09
29.07.2013Renewal fee patent year 10
28.07.2014Renewal fee patent year 11
23.07.2015Renewal fee patent year 12
22.07.2016Renewal fee patent year 13
24.07.2017Renewal fee patent year 14
09.07.2018Renewal fee patent year 15
Penalty fee
Additional fee for renewal fee
31.07.201916   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]  - LAGOS-QUINTANA M ET AL, "Identification of Tissue-Specific MicroRNAs from Mouse", CURRENT BIOLOGY, (20020430), vol. 12, no. 9, ISSN 0960-9822, pages 735 - 739, XP026073748 [A] 1-14,23-26,29-30,34,48-51 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0960-9822(02)00809-6
 [A]  - ALTMANN K-H ET AL, NOVEL CHEMISTRY, APPLIED ANTISENSE OLIGONUCLEOTIDE TECHNOLOGY, WILEY-LISS, CHICHESTER, GB, PAGE(S) 73 - 107, (19980101), ISBN 9780471172796, XP002119324 [A] 1-13
 [AD]  - LIN K-Y ET AL, "A cytosine analogue capable of clamp-like binding to a guanine in helical nucleic acids", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (19980826), vol. 120, no. 33, ISSN 0002-7863, pages 8531 - 8532, XP002994711 [AD] 8 * the whole document *

DOI:   http://dx.doi.org/10.1021/ja981286z
 [T]  - CHANG JINHONG ET AL, "miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1", RNA BIOLOGY, (20040701), vol. 1, no. 2, pages 106 - 113, XP002544785
International search[X]WO03029459  (MAX PLANCK GES ZUR [DE], et al)
otherWO03029459
 WO2005107816
 EP1931782
    - BOUTLA A. ET AL, "Developmental defects by antisense-mediated inactivation of micr-RNAs 2 and 13 in Drosophila and the identification of putative target genes", NUCLEIC ACIDS RESEARCH, (2003), vol. 31, no. 17, pages 4973 - 4980, XP002993014

DOI:   http://dx.doi.org/10.1093/nar/gkg707
    - MEISTER G. ET AL, "Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing", RNA, (2004), vol. 10, pages 544 - 550, XP002376645

DOI:   http://dx.doi.org/10.1261/rna.5235104
    - ESAU C. ET AL, KEYSTONE SYMPOSIUM "SIRNAS AND MIRNAS", (20040414), page 117 (ABSTRACT), XP003031911
    - CHANG J. ET AL, "miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1", RNA BIOLOGY, (2004), vol. 1, no. 2, pages 106 - 113, XP002591841
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.