Extract from the Register of European Patents

EP About this file: EP2041177

EP2041177 - HIGH AFFINITY ANTIBODIES TO HUMAN IL-6 RECEPTOR [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  19.10.2012
Database last updated on 01.04.2026
Most recent event   Tooltip03.05.2013Lapse of the patent in a contracting statepublished on 05.06.2013  [2013/23]
Applicant(s)For all designated states
REGENERON PHARMACEUTICALS, INC.
777 Old Saw Mill River Road
Tarrytown, NY 10591 / US
[2009/14]
Inventor(s)01 / STEVENS, Sean
3001 Lexington Avenue
Mohegan Lake, NY 10547 / US
02 / HUANG, Tammy T.
10 Green Hill Road
Golden Bridge, NY 10526 / US
03 / MARTIN, Joel H.
244 Church Road
Putnam Valley, NY 10579 / US
04 / FAIRHURST, Jeanette L.
23 Parkview Court
White Plains, NY 10603 / US
05 / RAFIQUE, Ashique
99 Franklin Avenue
Yonkers, NY 10705 / US
06 / SMITH, Eric
230 East 30th, Street, Apt.5E
New York, NY 10016 / US
07 / POBURSKY, Kevin J.
60 Anderson Street
Beacon, NY 12508 / US
08 / PAPADOPOULOS, Nicholas J.
59 Heritage Lane
Lagrangeville, NY 12540 / US
09 / FANDL, James P.
40 Amanda's Way
Lagrangeville, NY 12540 / US
10 / CHEN, Gang
2478 Mill Pond Road
Yorktown Heights, NY 10598 / US
11 / KAROW, Margaret
12655 Ridge Drive
Camarillo, CA 93012 / US
 [2009/14]
Representative(s)Bentham, Andrew
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[N/P]
Former [2011/50]Bentham, Andrew
J.A. Kemp & Co. 14 South Square Gray's Inn
London WC1R 5JJ / GB
Former [2009/14]Bentham, Andrew
J.A. Kemp & Co. 14 South Square Gray's Inn
London WC1R 5JJ / GB
Application number, filing date07777380.201.06.2007
[2009/14]
WO2007US13062
Priority number, dateUS20060810664P02.06.2006         Original published format: US 810664 P
US20060843232P08.09.2006         Original published format: US 843232 P
[2009/14]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007143168
Date:13.12.2007
Language:EN
[2007/50]
Type: A2 Application without search report 
No.:EP2041177
Date:01.04.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 13.12.2007 takes the place of the publication of the European patent application.
[2009/14]
Type: B1 Patent specification 
No.:EP2041177
Date:14.12.2011
Language:EN
[2011/50]
Search report(s)International search report - published on:EP24.04.2008
ClassificationIPC:C07K16/28, C12N15/13, A61K39/00
[2009/14]
CPC:
C07K16/2866 (EP,KR,NO,US); A61K40/00 (KR); A61P1/00 (EP);
A61P1/04 (EP,KR); A61P19/02 (EP,KR); A61P29/00 (EP,KR);
A61P37/00 (EP); A61P37/02 (EP,KR); C07K16/26 (KR);
C12N15/11 (KR); A61K2039/505 (EP,KR,NO,US); C07K2317/14 (KR,NO,US);
C07K2317/21 (EP,KR,NO,US); C07K2317/56 (NO,US); C07K2317/565 (KR,NO,US);
C07K2317/76 (EP,KR,NO,US); C07K2317/92 (EP,KR,NO,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/14]
Extension statesAL24.11.2008
BA24.11.2008
HR24.11.2008
MK24.11.2008
RS24.11.2008
TitleGerman:HOCHAFFINE ANTIKÖRPER GEGEN DEN HUMANEN IL-6-REZEPTOR[2009/14]
English:HIGH AFFINITY ANTIBODIES TO HUMAN IL-6 RECEPTOR[2009/14]
French:ANTICORPS DIRIGÉS CONTRE LE RÉCEPTEUR DE L'IL-6 HUMAINE, À AFFINITÉ ÉLEVÉE POUR LEDIT RÉCEPTEUR[2009/14]
Entry into regional phase24.11.2008National basic fee paid 
24.11.2008Designation fee(s) paid 
24.11.2008Examination fee paid 
Examination procedure24.11.2008Examination requested  [2009/14]
30.01.2009Amendment by applicant (claims and/or description)
21.01.2011Despatch of a communication from the examining division (Time limit: M04)
20.04.2011Reply to a communication from the examining division
10.06.2011Communication of intention to grant the patent
27.09.2011Fee for grant paid
27.09.2011Fee for publishing/printing paid
Divisional application(s)EP11171039.8  / EP2374818
EP12191147.3   Application deemed to be withdrawn  : 04.12.2012
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  21.01.2011
Opposition(s)17.09.2012No opposition filed within time limit [2012/47]
Fees paidRenewal fee
26.06.2009Renewal fee patent year 03
25.06.2010Renewal fee patent year 04
27.06.2011Renewal fee patent year 05
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Lapses during opposition  TooltipSK01.06.2012
[2013/23]
Cited inInternational search[Y]   MIHARA ET AL: "Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family", INTERNATIONAL IMMUNOPHARMACOLOGY, ELSEVIER, AMSTERDAM, NL, vol. 5, no. 12, November 2005 (2005-11-01), pages 1731 - 1740, XP005020014, ISSN: 1567-5769 [Y] 1-19 * the whole document *
 [PY]   PAUL-PLETZER KALANETHEE: "Tocilizumab: Blockade of interleukin-6 signaling pathway as a therapeutic strategy for inflammatory disorders", DRUGS OF TODAY, vol. 42, no. 9, September 2006 (2006-09-01), pages 559 - 576, XP002462414, ISSN: 1699-3993 [PY] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1358/dot.2006.42.9.1025692
by applicant  REDDY ET AL., J. IMMUNOL., vol. 164, 2000, pages 1925 - 1933
   HOLLIGER ET AL., PROC. NATL. ACAD SCI. USA, vol. 90, 1993, pages 6444 - 6448
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