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Extract from the Register of European Patents

EP About this file: EP2059598

EP2059598 - COMPOSITIONS AND METHODS FOR MODULATING AMPA RECEPTOR-MEDIATED EXCITOTOXICITY [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  23.01.2015
Database last updated on 24.04.2024
Most recent event   Tooltip15.07.2016Lapse of the patent in a contracting state
New state(s): TR		published on 17.08.2016  [2016/33]
Applicant(s)For all designated states
Centre for Addiction and Mental Health
33 Russell Street
Toronto, ON M5S 2S1 / CA
[2009/21]
Inventor(s)01 / LIU, Fang
c/o Centre For Addiction and Mental Health
33 Russell Street
Toronto, Ontario M5S 2S1 / CA
 [2014/12]
Former [2009/21]01 / LIU, Fang
c/o Centre For Addiction and Mental Health 33 Russell Street
Toronto, Ontario M5S 2S1 / CA
Representative(s)Murphy, Colm Damien
Venner Shipley LLP
200 Aldersgate
London EC1A 4HD / GB
[2014/21]
Former [2010/51]Murphy, Colm Damien, et al
Ipulse 26 Mallinson Road London
SW11 1BP / GB
Former [2009/21]Murphy, Colm Damien, et al
Ipulse 26 Mallinson Road London
SW11 1BP / GB
Application number, filing date07800563.431.08.2007
[2009/21]
WO2007CA01539
Priority number, dateUS20060841195P31.08.2006         Original published format: US 841195 P
[2009/21]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008025163
Date:06.03.2008
Language:EN
[2008/10]
Type: A1 Application with search report 
No.:EP2059598
Date:20.05.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 06.03.2008 takes the place of the publication of the European patent application.
[2009/21]
Type: B1 Patent specification 
No.:EP2059598
Date:19.03.2014
Language:EN
[2014/12]
Search report(s)International search report - published on:CA06.03.2008
(Supplementary) European search report - dispatched on:EP22.12.2009
ClassificationIPC:C12N15/53, A61K38/17, A61K48/00, A61P39/00, C07K14/47, C07K14/705, C07K17/00, C07K19/00, C12N15/12, C12N9/02
[2009/21]
CPC:
C07K14/70571 (EP,US); A61P25/00 (EP); A61P25/08 (EP);
A61P39/00 (EP); A61K38/00 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/21]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:ZUSAMMENSETZUNGEN UND VERFAHREN ZUR MODULATION VON AMPA-REZEPTOR-VERMITTELTER EXZITOTOXIZITÄT[2009/21]
English:COMPOSITIONS AND METHODS FOR MODULATING AMPA RECEPTOR-MEDIATED EXCITOTOXICITY[2009/21]
French:COMPOSITIONS ET PROCÉDÉS POUR LA MODULATION DE L'EXCITOTOXICITÉ INDUITE PAR LE RÉCEPTEUR AMPA[2009/21]
Entry into regional phase26.03.2009National basic fee paid 
26.03.2009Search fee paid 
26.03.2009Designation fee(s) paid 
26.03.2009Examination fee paid 
Examination procedure26.03.2009Amendment by applicant (claims and/or description)
26.03.2009Examination requested  [2009/21]
15.03.2010Despatch of a communication from the examining division (Time limit: M06)
10.09.2010Reply to a communication from the examining division
21.09.2010Despatch of a communication from the examining division (Time limit: M04)
01.02.2011Reply to a communication from the examining division
02.12.2011Despatch of a communication from the examining division (Time limit: M04)
30.03.2012Reply to a communication from the examining division
27.11.2013Communication of intention to grant the patent
28.01.2014Fee for grant paid
28.01.2014Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  15.03.2010
Opposition(s)22.12.2014No opposition filed within time limit [2015/09]
Fees paidRenewal fee
05.08.2009Renewal fee patent year 03
31.08.2010Renewal fee patent year 04
26.08.2011Renewal fee patent year 05
28.08.2012Renewal fee patent year 06
12.09.2013Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
31.08.201307   M06   Fee paid on   12.09.2013
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU31.08.2007
AT19.03.2014
BE19.03.2014
CY19.03.2014
CZ19.03.2014
DK19.03.2014
EE19.03.2014
ES19.03.2014
FI19.03.2014
IT19.03.2014
LT19.03.2014
LV19.03.2014
MC19.03.2014
MT19.03.2014
NL19.03.2014
PL19.03.2014
RO19.03.2014
SE19.03.2014
SI19.03.2014
SK19.03.2014
TR19.03.2014
BG19.06.2014
GR20.06.2014
IS19.07.2014
PT21.07.2014
CH31.08.2014
GB31.08.2014
IE31.08.2014
LI31.08.2014
LU31.08.2014
FR01.09.2014
[2016/33]
Former [2016/32]HU31.08.2007
AT19.03.2014
BE19.03.2014
CY19.03.2014
CZ19.03.2014
DK19.03.2014
EE19.03.2014
ES19.03.2014
FI19.03.2014
IT19.03.2014
LT19.03.2014
LV19.03.2014
MC19.03.2014
MT19.03.2014
NL19.03.2014
PL19.03.2014
RO19.03.2014
SE19.03.2014
SI19.03.2014
SK19.03.2014
BG19.06.2014
GR20.06.2014
IS19.07.2014
PT21.07.2014
CH31.08.2014
GB31.08.2014
IE31.08.2014
LI31.08.2014
LU31.08.2014
FR01.09.2014
Former [2016/28]AT19.03.2014
BE19.03.2014
CY19.03.2014
CZ19.03.2014
DK19.03.2014
EE19.03.2014
ES19.03.2014
FI19.03.2014
IT19.03.2014
LT19.03.2014
LV19.03.2014
MC19.03.2014
MT19.03.2014
NL19.03.2014
PL19.03.2014
RO19.03.2014
SE19.03.2014
SI19.03.2014
SK19.03.2014
BG19.06.2014
GR20.06.2014
IS19.07.2014
PT21.07.2014
CH31.08.2014
GB31.08.2014
IE31.08.2014
LI31.08.2014
LU31.08.2014
FR01.09.2014
Former [2015/38]AT19.03.2014
BE19.03.2014
CY19.03.2014
CZ19.03.2014
DK19.03.2014
EE19.03.2014
ES19.03.2014
FI19.03.2014
IT19.03.2014
LT19.03.2014
LV19.03.2014
MC19.03.2014
NL19.03.2014
PL19.03.2014
RO19.03.2014
SE19.03.2014
SI19.03.2014
SK19.03.2014
BG19.06.2014
IS19.07.2014
PT21.07.2014
CH31.08.2014
GB31.08.2014
IE31.08.2014
LI31.08.2014
LU31.08.2014
FR01.09.2014
Former [2015/37]AT19.03.2014
BE19.03.2014
CY19.03.2014
CZ19.03.2014
DK19.03.2014
EE19.03.2014
ES19.03.2014
FI19.03.2014
IT19.03.2014
LT19.03.2014
LV19.03.2014
MC19.03.2014
NL19.03.2014
PL19.03.2014
RO19.03.2014
SE19.03.2014
SI19.03.2014
SK19.03.2014
BG19.06.2014
IS19.07.2014
PT21.07.2014
CH31.08.2014
GB31.08.2014
IE31.08.2014
LI31.08.2014
LU31.08.2014
Former [2015/36]AT19.03.2014
BE19.03.2014
CY19.03.2014
CZ19.03.2014
DK19.03.2014
EE19.03.2014
ES19.03.2014
FI19.03.2014
IT19.03.2014
LT19.03.2014
LV19.03.2014
MC19.03.2014
NL19.03.2014
PL19.03.2014
RO19.03.2014
SE19.03.2014
SI19.03.2014
SK19.03.2014
BG19.06.2014
IS19.07.2014
PT21.07.2014
CH31.08.2014
GB31.08.2014
LI31.08.2014
LU31.08.2014
Former [2015/20]AT19.03.2014
BE19.03.2014
CY19.03.2014
CZ19.03.2014
DK19.03.2014
EE19.03.2014
ES19.03.2014
FI19.03.2014
IT19.03.2014
LT19.03.2014
LV19.03.2014
MC19.03.2014
NL19.03.2014
PL19.03.2014
RO19.03.2014
SE19.03.2014
SK19.03.2014
BG19.06.2014
IS19.07.2014
PT21.07.2014
CH31.08.2014
LI31.08.2014
LU31.08.2014
Former [2015/19]AT19.03.2014
BE19.03.2014
CY19.03.2014
CZ19.03.2014
DK19.03.2014
EE19.03.2014
ES19.03.2014
FI19.03.2014
IT19.03.2014
LT19.03.2014
LV19.03.2014
MC19.03.2014
NL19.03.2014
PL19.03.2014
RO19.03.2014
SE19.03.2014
SK19.03.2014
BG19.06.2014
IS19.07.2014
PT21.07.2014
LU31.08.2014
Former [2015/18]AT19.03.2014
BE19.03.2014
CY19.03.2014
CZ19.03.2014
DK19.03.2014
EE19.03.2014
ES19.03.2014
FI19.03.2014
IT19.03.2014
LT19.03.2014
LV19.03.2014
MC19.03.2014
NL19.03.2014
PL19.03.2014
RO19.03.2014
SE19.03.2014
SK19.03.2014
BG19.06.2014
IS19.07.2014
PT21.07.2014
Former [2015/08]AT19.03.2014
BE19.03.2014
CY19.03.2014
CZ19.03.2014
DK19.03.2014
EE19.03.2014
ES19.03.2014
FI19.03.2014
LT19.03.2014
LV19.03.2014
NL19.03.2014
PL19.03.2014
RO19.03.2014
SE19.03.2014
SK19.03.2014
BG19.06.2014
IS19.07.2014
PT21.07.2014
Former [2015/02]AT19.03.2014
BE19.03.2014
CY19.03.2014
CZ19.03.2014
EE19.03.2014
ES19.03.2014
FI19.03.2014
LT19.03.2014
LV19.03.2014
NL19.03.2014
PL19.03.2014
RO19.03.2014
SE19.03.2014
SK19.03.2014
BG19.06.2014
IS19.07.2014
PT21.07.2014
Former [2014/51]AT19.03.2014
BE19.03.2014
CY19.03.2014
CZ19.03.2014
EE19.03.2014
ES19.03.2014
FI19.03.2014
LT19.03.2014
LV19.03.2014
NL19.03.2014
PL19.03.2014
RO19.03.2014
SE19.03.2014
SK19.03.2014
BG19.06.2014
IS19.07.2014
Former [2014/50]BE19.03.2014
CY19.03.2014
CZ19.03.2014
EE19.03.2014
ES19.03.2014
FI19.03.2014
LT19.03.2014
LV19.03.2014
NL19.03.2014
PL19.03.2014
RO19.03.2014
SE19.03.2014
SK19.03.2014
BG19.06.2014
IS19.07.2014
Former [2014/49]BE19.03.2014
CY19.03.2014
CZ19.03.2014
EE19.03.2014
FI19.03.2014
LT19.03.2014
LV19.03.2014
RO19.03.2014
SE19.03.2014
BG19.06.2014
IS19.07.2014
Former [2014/48]BE19.03.2014
CY19.03.2014
CZ19.03.2014
EE19.03.2014
FI19.03.2014
LT19.03.2014
LV19.03.2014
SE19.03.2014
BG19.06.2014
Former [2014/46]BE19.03.2014
CY19.03.2014
FI19.03.2014
LT19.03.2014
LV19.03.2014
SE19.03.2014
Former [2014/41]CY19.03.2014
FI19.03.2014
LT19.03.2014
LV19.03.2014
SE19.03.2014
Former [2014/37]CY19.03.2014
FI19.03.2014
LT19.03.2014
SE19.03.2014
Former [2014/36]LT19.03.2014
Documents cited:Search[XI]  - BERETTA F ET AL, "NSF interaction is important for direct insertion of GluR2 at synaptic sites", MOLECULAR AND CELLULAR NEUROSCIENCES, SAN DIEGO, US, (20050401), vol. 28, no. 4, ISSN 1044-7431, pages 650 - 660, XP004801864 [X] 1-2,10,12-15 * the whole document * [I] 7

DOI:   http://dx.doi.org/10.1016/j.mcn.2004.11.008
 [XI]  - LEE SANG HYOUNG ET AL, "Clathrin adaptor AP2 and NSF interact with overlapping sites of GluR2 and play distinct roles in AMPA receptor trafficking and hippocampal LTD.", NEURON, (20021114), vol. 36, no. 4, ISSN 0896-6273, pages 661 - 674, XP002555891 [X] 1-2 * the whole document * [I] 7

DOI:   http://dx.doi.org/10.1016/S0896-6273(02)01024-3
International search[X]US2003203372  (WARD NEIL RAYMOND [GB], et al);
 [A]US2004086891  (TATTON WILLIAM G [US], et al);
 [X]WO2005033311  (UNIV BRITISH COLUMBIA [CA], et al);
 [A]  - CHUANG D.-M. ET AL., "Gyceraldehyde-3-phosphate dehydrogenase, apoptosis and neurodegenerative diseases", ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, (20050207), vol. 45, pages 269 - 290, XP002362597
 [A]  - AARTS M.M. ET AL., "Novel concepts in excitotoxic neurodegeneration after stroke", EXPERT IN REVIEWS IN MOLECULAR MEDICINE, (20031216), vol. 5, no. 30, pages 1 - 22, XP008104853

DOI:   http://dx.doi.org/10.1017/S1462399403007087
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