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Extract from the Register of European Patents

EP About this file: EP2298768

EP2298768 - 5-amino-2,4,7-trioxo-3,4,7,8-tetrahydro-2H-pyrido[2,3-d]pyrimidine derivatives and related compounds for the treatment of cancer [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  20.09.2013
Database last updated on 01.04.2026
Most recent event   Tooltip24.01.2014Change - lapse in a contracting state
State(s) deleted from list of lapses: CY		published on 26.02.2014  [2014/09]
Applicant(s)For all designated states
Japan Tobacco, Inc.
2-1, Toranomon 2-chome, Minato-ku
Tokyo 105-8422 / JP
[2011/12]
Inventor(s)01 / Kawasaki, Hisashi
Cen.Pharm.Res.Inst.of Japan Tobacco Inc.
1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
02 / Abe, Hiroyuki
Cen. Pharm. Res. Inst. of Japan Tobacco Inc.
1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
03 / Hayakawa, Kazuhide
Cen. Pharm. Res. Inst. of Japan Tobacco Inc.
1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
04 / Iida, Tetsuya
Cen. Pharm. Res. Inst. of Japan Tobacco Inc.
1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
05 / Kikuchi, Shinichi
Cen. Pharm. Res. Inst. of Japan Tobacco Inc.
1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
06 / Yamaguchi, Takayuki
Cen. Pharm. Res. Inst. of Japan Tobacco Inc.
1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
07 / Nanayama, Toyomichi
Cen. Pharm. Res. Inst. of Japan Tobacco Inc.
1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
08 / Kurachi, Hironori
Cen. Pharm. Res. Inst. of Japan Tobacco Inc.
1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
09 / Tamaru, Masahiro
Cen. Pharm. Res. Inst. of Japan Tobacco Inc.
1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
10 / Hori, Yoshikazu
Cen. Pharm. Res. Inst. of Japan Tobacco Inc.
1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
11 / Takahashi, Mitsuru
Cen. Pharm. Res. Inst. of Japan Tobacco Inc.
1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
12 / Yoshida, Takayuki
Cen. Pharm. Res. Inst. of Japan Tobacco Inc.
13-2, Fukuura 1-chome
Kanazawa-ku
Yokohama-shi Kanagawa 2360004 / JP
13 / Sakai, Toshiyuki
28-11, Kowaki-cho
Matsugasaki
Sakyo-ku
Kyoto-shi Kyoto 6060957 / JP
 [2012/46]
Former [2011/12]01 / Kawasaki, Hisashi
Cen.Pharm.Res.Inst.of Japan Tobacco Inc. 1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
02 / Abe, Hiroyuki
Cen. Pharm. Res. Inst. of Japan Tobacco Inc. 1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
03 / Hayakawa, Kazuhide
Cen. Pharm. Res. Inst. of Japan Tobacco Inc. 1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
04 / Iida, Tetsuya
Cen. Pharm. Res. Inst. of Japan Tobacco Inc. 1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
05 / Kikuchi, Shinichi
Cen. Pharm. Res. Inst. of Japan Tobacco Inc. 1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
06 / Yamaguchi, Takayuki
Cen. Pharm. Res. Inst. of Japan Tobacco Inc. 1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
07 / Nanayama, Toyomichi
Cen. Pharm. Res. Inst. of Japan Tobacco Inc. 1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
08 / Kurachi, Hironori
Cen. Pharm. Res. Inst. of Japan Tobacco Inc. 1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
09 / Tamaru, Masahiro
Cen. Pharm. Res. Inst. of Japan Tobacco Inc. 1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
10 / Hori, Yoshikazu
Cen. Pharm. Res. Inst. of Japan Tobacco Inc. 1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
11 / Takahashi, Mitsuru
Cen. Pharm. Res. Inst. of Japan Tobacco Inc. 1-1, Murasaki-cho
Takatsuki-shi Osaka 5691125 / JP
12 / Yoshida, Takayuki
Cen. Pharm. Res. Inst. of Japan Tobacco Inc. 13-2, Fukuura 1-chome Kanazawa-ku
Yokohama-shi Kanagawa 2360004 / JP
13 / Sakai, Toshiyuki
28-11, Kowaki-cho Matsugasaki Sakyo-ku
Kyoto-shi Kyoto 6060957 / JP
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2012/46]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Former [2011/12]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Application number, filing date10013055.810.06.2005
[2011/12]
Priority number, dateJP2004017477011.06.2004         Original published format: JP 2004174770
JP2004032711110.11.2004         Original published format: JP 2004327111
[2011/12]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2298768
Date:23.03.2011
Language:EN
[2011/12]
Type: B1 Patent specification 
No.:EP2298768
Date:14.11.2012
Language:EN
[2012/46]
Type: B9 Corrected patent specification 
No.:EP2298768
Date:24.04.2013
[2013/17]
Search report(s)(Supplementary) European search report - dispatched on:EP17.02.2011
ClassificationIPC:C07D471/04, C07D487/04
[2011/12]
CPC:
C07D487/04 (EP,NO); C07D471/04 (EP,KR,NO); A61P11/00 (EP);
A61P17/06 (EP); A61P19/02 (EP); A61P19/08 (EP);
A61P25/32 (EP); A61P29/00 (EP); A61P31/04 (EP);
A61P31/12 (EP); A61P31/18 (EP); A61P31/22 (EP);
A61P35/00 (EP); A61P35/02 (EP); A61P37/06 (EP);
A61P43/00 (EP); A61P9/04 (EP); A61P9/10 (EP) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2011/12]
Extension statesAL15.09.2011
BA15.09.2011
HR15.09.2011
LV15.09.2011
MK15.09.2011
YU15.09.2011
TitleGerman:5-amino-2,4,7-trioxo-3,4,7,8-tetrahydro-2H-pyrido[2,3-d]pyrimidin Derivate und verwandte Verbindungen zur Behandlung von Krebs[2011/12]
English:5-amino-2,4,7-trioxo-3,4,7,8-tetrahydro-2H-pyrido[2,3-d]pyrimidine derivatives and related compounds for the treatment of cancer[2011/12]
French:Dérivés 5-amino-2,4,7-trioxo-3,4,7,8-tetrahydro-2H-pyrido[2,3-d]pyrimidine et composés similaires pour le traitement de cancer[2011/12]
Examination procedure15.09.2011Examination requested  [2011/43]
23.09.2011Amendment by applicant (claims and/or description)
30.12.2011Communication of intention to grant the patent
09.05.2012Fee for grant paid
09.05.2012Fee for publishing/printing paid
Parent application(s)   TooltipEP05751244.4  / EP1761528
EP07018816.4  / EP1894932
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20050751244) is  19.04.2007
Opposition(s)15.08.2013No opposition filed within time limit [2013/43]
Fees paidRenewal fee
28.01.2011Renewal fee patent year 03
28.01.2011Renewal fee patent year 04
28.01.2011Renewal fee patent year 05
28.01.2011Renewal fee patent year 06
27.06.2011Renewal fee patent year 07
27.03.2012Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  Tooltipdeleted
[2014/09]
Former [2013/52]CY14.11.2012
Documents cited:Search[A] WO0203997  (ICN PHARMACEUTICALS et al.)
 [A] WO03062236  (WARNER LAMBERT CO et al.)
 [AD] WO02094824  (CELL THERAPEUTICS INC et al.)
 [A]   DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 1996, KHATTAB, AHMED F. A. ET AL: "Ring closure reaction of 5-hydroxypyrido[2,3-d]pyrimidine-2,4,7- triones to benzo[b]pyrimido[4,5-h]1,6-naphthyridine-1,3,6-triones", XP002343581, retrieved from STN Database accession no. 1996:147520
 [A]   JOURNAL FR PRAKTISCHE CHEMIE - CHEMIKER-ZEITUNG, vol. 338, no. 2, 1996, pages 151 - 156, ISSN: 0941-1216
by applicantJP2003504401
 WO0105393
 JP2002332247
 CA2385412
 JP2002532414
 WO0035435
 JP2002532415
 WO0035436
 JP2002534380
 WO0040235
 JP2002534381
 WO0040237
 WO02087620
 US2004138285
 WO0206520
 JP2004504294
 WO0206213
 WO02094824
   LETTERS TO NATURE, vol. 371, 15 September 1994 (1994-09-15), pages 257 - 261
   FEBS LETTERS, vol. 554, 2003, pages 347 - 350
   THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 4, 2001, pages 2686 - 2692
   KHIMIIA GETEROTSIKLICHESKIKH SOEDINENII, 1991, pages 674 - 680
   CHEM. PHARM. BULL., vol. 9, no. 21, 1973, pages 2014 - 2018
   JOURNAL FUR PRAKTISCHE CHEMIE, vol. 338, 1996, pages 151 - 156
   JOURNAL OF MEDICINAL CHEMISTRY, vol. 29, no. 5, 1986, pages 709 - 715
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.