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Extract from the Register of European Patents

EP About this file: EP2464654

EP2464654 - THIOL PROTECTING GROUP [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  14.08.2015
Database last updated on 09.04.2026
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
UCL Business PLC
The Network Building 97 Tottenham Court Road
London W1T 4TP / GB
[2012/25]
Inventor(s)01 / SMITH, Mark
UCL Business PLC The Network Building
97 Tottenham Court Road
London W1T 4TP / GB
02 / CADDICK, Stephen
UCL Business PLC The Network Building
97 Tottenham Court Road
London W1T 4TP / GB
03 / BAKER, James
UCL Business PLC The Network Building
97 Tottenham Court Road
London W1T 4TP / GB
04 / CHUDASAMA, Vijay
UCL Business PLC The Network Building
97 Tottenham Court Road
London W1T 4TP / GB
 [2014/38]
Former [2012/25]01 / SMITH, Mark
UCL Business PLC The Network Building
97 Tottenham Court Road
London W1T 4TP / GB
02 / CADDICK, Stephen
UCL Business PLC The Network Building
97 Tottenham Court Road
London W1T 4TP / GB
03 / BAKER, James
UCL Business PLC The Network Building
97 Tottenham Court Road
London W1T 4TP / GB
Representative(s)Srinivasan, Ravi Chandran
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[2012/25]
Application number, filing date10747930.509.08.2010
WO2010GB01500
Priority number, dateGB2009001396510.08.2009         Original published format: GB 0913965
GB2009001396710.08.2009         Original published format: GB 0913967
GB2009001432114.08.2009         Original published format: GB 0914321
[2012/25]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2011018612
Date:17.02.2011
Language:EN
[2011/07]
Type: A2 Application without search report 
No.:EP2464654
Date:20.06.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 17.02.2011 takes the place of the publication of the European patent application.
[2012/25]
Type: B1 Patent specification 
No.:EP2464654
Date:08.10.2014
Language:EN
[2014/41]
Search report(s)International search report - published on:EP14.04.2011
ClassificationIPC:C07K1/00, A61L27/28
[2012/25]
CPC:
A61K49/0017 (EP,US); A61K47/545 (US); A61K47/551 (EP,US);
A61K47/60 (EP,US); A61K47/62 (EP,US); A61P1/04 (EP);
A61P1/08 (EP); A61P11/00 (EP); A61P11/14 (EP);
A61P13/00 (EP); A61P21/02 (EP); A61P23/02 (EP);
A61P25/00 (EP); A61P25/04 (EP); A61P25/08 (EP);
A61P25/22 (EP); A61P25/24 (EP); A61P29/00 (EP);
A61P3/06 (EP); A61P31/04 (EP); A61P31/10 (EP);
A61P31/12 (EP); A61P35/00 (EP); A61P37/04 (EP);
A61P37/06 (EP); A61P43/00 (EP); A61P5/00 (EP);
A61P7/02 (EP); A61P9/06 (EP); A61P9/12 (EP);
C07D207/416 (EP,US); C07D207/456 (EP,US); C07D209/52 (EP,US);
C07K14/435 (US); C07K14/655 (EP,US); G01N33/58 (US);
Y02P20/55 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2012/25]
Extension statesBANot yet paid
MENot yet paid
RSNot yet paid
TitleGerman:THIOL-SCHUTZGRUPPE[2012/25]
English:THIOL PROTECTING GROUP[2012/25]
French:GROUPEMENT PROTECTEUR THIOL[2012/25]
Entry into regional phase09.03.2012National basic fee paid 
09.03.2012Designation fee(s) paid 
09.03.2012Examination fee paid 
Examination procedure09.03.2012Amendment by applicant (claims and/or description)
09.03.2012Examination requested  [2012/25]
25.06.2013Despatch of a communication from the examining division (Time limit: M06)
20.12.2013Reply to a communication from the examining division
12.03.2014Communication of intention to grant the patent
14.07.2014Fee for grant paid
14.07.2014Fee for publishing/printing paid
14.07.2014Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  25.06.2013
Opposition(s)09.07.2015No opposition filed within time limit [2015/38]
Fees paidRenewal fee
29.08.2012Renewal fee patent year 03
28.08.2013Renewal fee patent year 04
26.08.2014Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU09.08.2010
AL08.10.2014
AT08.10.2014
BE08.10.2014
BG08.10.2014
CY08.10.2014
CZ08.10.2014
DK08.10.2014
EE08.10.2014
ES08.10.2014
FI08.10.2014
HR08.10.2014
IT08.10.2014
LT08.10.2014
LV08.10.2014
MC08.10.2014
MK08.10.2014
MT08.10.2014
NL08.10.2014
PL08.10.2014
RO08.10.2014
SE08.10.2014
SI08.10.2014
SK08.10.2014
SM08.10.2014
TR08.10.2014
NO08.01.2015
GR09.01.2015
IS08.02.2015
PT09.02.2015
[2018/46]
Former [2018/30]HU09.08.2010
AT08.10.2014
BE08.10.2014
BG08.10.2014
CY08.10.2014
CZ08.10.2014
DK08.10.2014
EE08.10.2014
ES08.10.2014
FI08.10.2014
HR08.10.2014
IT08.10.2014
LT08.10.2014
LV08.10.2014
MC08.10.2014
MK08.10.2014
MT08.10.2014
NL08.10.2014
PL08.10.2014
RO08.10.2014
SE08.10.2014
SI08.10.2014
SK08.10.2014
SM08.10.2014
TR08.10.2014
NO08.01.2015
GR09.01.2015
IS08.02.2015
PT09.02.2015
Former [2017/46]HU09.08.2010
AT08.10.2014
BE08.10.2014
BG08.10.2014
CY08.10.2014
CZ08.10.2014
DK08.10.2014
EE08.10.2014
ES08.10.2014
FI08.10.2014
HR08.10.2014
IT08.10.2014
LT08.10.2014
LV08.10.2014
MC08.10.2014
MT08.10.2014
NL08.10.2014
PL08.10.2014
RO08.10.2014
SE08.10.2014
SI08.10.2014
SK08.10.2014
SM08.10.2014
TR08.10.2014
NO08.01.2015
GR09.01.2015
IS08.02.2015
PT09.02.2015
Former [2017/38]HU09.08.2010
AT08.10.2014
BG08.10.2014
CY08.10.2014
CZ08.10.2014
DK08.10.2014
EE08.10.2014
ES08.10.2014
FI08.10.2014
HR08.10.2014
IT08.10.2014
LT08.10.2014
LV08.10.2014
MC08.10.2014
MT08.10.2014
NL08.10.2014
PL08.10.2014
RO08.10.2014
SE08.10.2014
SI08.10.2014
SK08.10.2014
SM08.10.2014
TR08.10.2014
NO08.01.2015
GR09.01.2015
IS08.02.2015
PT09.02.2015
Former [2017/21]AT08.10.2014
CY08.10.2014
CZ08.10.2014
DK08.10.2014
EE08.10.2014
ES08.10.2014
FI08.10.2014
HR08.10.2014
IT08.10.2014
LT08.10.2014
LV08.10.2014
MC08.10.2014
MT08.10.2014
NL08.10.2014
PL08.10.2014
RO08.10.2014
SE08.10.2014
SI08.10.2014
SK08.10.2014
NO08.01.2015
GR09.01.2015
IS08.02.2015
PT09.02.2015
Former [2016/18]AT08.10.2014
CY08.10.2014
CZ08.10.2014
DK08.10.2014
EE08.10.2014
ES08.10.2014
FI08.10.2014
HR08.10.2014
IT08.10.2014
LT08.10.2014
LV08.10.2014
MC08.10.2014
NL08.10.2014
PL08.10.2014
RO08.10.2014
SE08.10.2014
SI08.10.2014
SK08.10.2014
NO08.01.2015
GR09.01.2015
IS08.02.2015
PT09.02.2015
Former [2016/12]AT08.10.2014
CY08.10.2014
CZ08.10.2014
DK08.10.2014
EE08.10.2014
ES08.10.2014
FI08.10.2014
HR08.10.2014
IT08.10.2014
LT08.10.2014
LV08.10.2014
NL08.10.2014
PL08.10.2014
RO08.10.2014
SE08.10.2014
SI08.10.2014
SK08.10.2014
NO08.01.2015
GR09.01.2015
IS08.02.2015
PT09.02.2015
Former [2015/37]AT08.10.2014
CY08.10.2014
CZ08.10.2014
DK08.10.2014
EE08.10.2014
ES08.10.2014
FI08.10.2014
HR08.10.2014
IT08.10.2014
LT08.10.2014
LV08.10.2014
NL08.10.2014
PL08.10.2014
RO08.10.2014
SE08.10.2014
SK08.10.2014
NO08.01.2015
GR09.01.2015
IS08.02.2015
PT09.02.2015
Former [2015/36]AT08.10.2014
CY08.10.2014
CZ08.10.2014
DK08.10.2014
EE08.10.2014
ES08.10.2014
FI08.10.2014
HR08.10.2014
LT08.10.2014
LV08.10.2014
NL08.10.2014
PL08.10.2014
RO08.10.2014
SE08.10.2014
NO08.01.2015
GR09.01.2015
IS08.02.2015
PT09.02.2015
Former [2015/35]AT08.10.2014
CY08.10.2014
DK08.10.2014
EE08.10.2014
ES08.10.2014
FI08.10.2014
HR08.10.2014
LT08.10.2014
LV08.10.2014
NL08.10.2014
PL08.10.2014
SE08.10.2014
NO08.01.2015
GR09.01.2015
IS08.02.2015
PT09.02.2015
Former [2015/26]AT08.10.2014
CY08.10.2014
ES08.10.2014
FI08.10.2014
HR08.10.2014
LT08.10.2014
LV08.10.2014
NL08.10.2014
PL08.10.2014
SE08.10.2014
NO08.01.2015
GR09.01.2015
IS08.02.2015
PT09.02.2015
Former [2015/25]AT08.10.2014
ES08.10.2014
FI08.10.2014
HR08.10.2014
LT08.10.2014
LV08.10.2014
NL08.10.2014
PL08.10.2014
SE08.10.2014
NO08.01.2015
GR09.01.2015
IS08.02.2015
PT09.02.2015
Former [2015/24]ES08.10.2014
FI08.10.2014
HR08.10.2014
LT08.10.2014
LV08.10.2014
NL08.10.2014
PL08.10.2014
SE08.10.2014
NO08.01.2015
GR09.01.2015
IS08.02.2015
PT09.02.2015
Former [2015/23]ES08.10.2014
FI08.10.2014
LT08.10.2014
NL08.10.2014
NO08.01.2015
IS08.02.2015
PT09.02.2015
Former [2015/22]LT08.10.2014
NL08.10.2014
NO08.01.2015
PT09.02.2015
Former [2015/21]LT08.10.2014
NL08.10.2014
NO08.01.2015
Former [2015/20]LT08.10.2014
NL08.10.2014
Former [2015/16]NL08.10.2014
Cited inInternational search[X]   COONEY D A ET AL: "Inhibition of L asparagine synthetase by mucochloric and mucobromic acids", ENZYME, vol. 21, no. 6, 1976, pages 524 - 539, XP008126942
 [X]   LEBETKIN E H ET AL: "Disposition of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in B6C3F1 mice and F344 rats.", JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH PART A, vol. 65, no. 24, 2002, pages 2101 - 2118, XP002612569

DOI:   http://dx.doi.org/10.1080/0098410029007152 2
 [X]   YONEYAMA K ET AL: "ANTAGONISTIC MECHANISM OF SULFHYDRYL COMPOUNDS ON CELLOCIDIN ACTIVITY", JOURNAL OF ANTIBIOTICS, vol. 31, no. 10, 1978, pages 1065 - 1066, XP002612570 * abstract *
 [AP]   SMITH M E B ET AL: "Protein modification, bioconjugation, and disulfide bridging using bromomaleimides.", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 132, no. 6, 17 February 2010 (2010-02-17), pages 1960 - 1965, XP002601596

DOI:   http://dx.doi.org/10.1021/JA908610S
 [AP]   TEDALDI L M ET AL: "Bromomaleimides: new reagents for the selective and reversible modification of cysteine.", CHEMICAL COMMUNICATIONS, no. 43, 21 November 2009 (2009-11-21), pages 6583 - 6585, XP002601597

DOI:   http://dx.doi.org/10.1039/B915136B
by applicant  JBIOL CHEM, vol. 275, 2000, pages 921 - 9
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.