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Extract from the Register of European Patents

EP About this file: EP2400018

EP2400018 - In tumours differentially expressed gene products and use of the same. [Right-click to bookmark this link]
Former [2011/52]In tumours differentially expressed gene products and use of the same
[2015/35]
StatusNo opposition filed within time limit
Status updated on  10.03.2017
Database last updated on 01.04.2026
Most recent event   Tooltip10.03.2017No opposition filed within time limitpublished on 12.04.2017  [2017/15]
Applicant(s)For all designated states
Ganymed Pharmaceuticals AG
An der Goldgrube 12
55131 Mainz / DE
[2015/23]
Former [2011/52]For all designated states
Ganymed Pharmaceuticals AG
Freiligrathstrasse 12
55131 Mainz / DE
Inventor(s)01 / Sahin, Ugur
Philipp-von-Zabern-Platz 1
55116 Mainz / DE
02 / Türeci, Özlem
Philipp-von-Zabern-Platz 1
55116 Mainz / DE
03 / Koslowski, Michael
Am Ried 23
85764 Oberschleißheim / DE
 [2013/09]
Former [2011/52]01 / Sahin, Ugur
Philipp-von-Zabern-Platz 1
55116 Mainz / DE
02 / Türeci, Özlem
Philipp-von-Zabern-Platz 1
55116 Mainz / DE
03 / Koslowski, Michael
Autogenstrasse 50
65933 Frankfurt / DE
Representative(s)Schnappauf, Georg, et al
ZSP Patentanwälte PartG mbB
Hansastraße 32
80686 München / DE
[N/P]
Former [2016/18]Schnappauf, Georg, et al
ZSP Patentanwälte PartG mbB
Radlkoferstrasse 2
81373 München / DE
Former [2011/52]Schnappauf, Georg, et al
Dr. Volker Vossius
Patent- und Rechtsanwaltskanzlei
Geibelstrasse 6
81679 München / DE
Application number, filing date11007329.321.11.2003
[2011/52]
Priority number, dateDE200215460122.11.2002         Original published format: DE 10254601
[2011/52]
Filing languageDE
Procedural languageDE
PublicationType: A2 Application without search report 
No.:EP2400018
Date:28.12.2011
Language:DE
[2011/52]
Type: A3 Search report 
No.:EP2400018
Date:02.05.2012
Language:DE
[2012/18]
Type: B1 Patent specification 
No.:EP2400018
Date:04.05.2016
Language:DE
[2016/18]
Search report(s)(Supplementary) European search report - dispatched on:EP02.04.2012
ClassificationIPC:C12N15/11, A61K39/395, C12N5/10, C07K14/47, C07K16/30, C07K16/32, A61K48/00, C07K16/18, G01N33/574
[2012/18]
CPC:
C07K14/47 (EP,CN,KR,US); A61K39/39558 (KR); A61K48/005 (CN);
C07K16/3076 (US); A61K39/0011 (CN); A61K39/395 (CN);
A61K47/549 (US); A61P1/04 (EP); A61P1/18 (EP);
A61P11/00 (EP); A61P13/08 (EP); A61P13/12 (EP);
A61P15/00 (EP); A61P17/00 (EP); A61P35/00 (EP,KR);
A61P43/00 (EP); C07K16/18 (EP,CN,KR,US); C07K16/30 (EP,KR,US);
C07K16/3023 (EP,US); C07K16/3046 (EP,US); C12Q1/6886 (CN);
G01N33/5011 (CN); G01N33/5017 (CN); G01N33/57557 (CN);
G01N33/5758 (EP,CN,US); A61K2039/505 (EP,KR,US); C07K2317/30 (KR,US);
C07K2317/34 (EP,KR,US); C12N2503/02 (CN); C12Q2600/136 (CN);
C12Q2600/158 (CN); G01N2500/10 (CN) (-)
Former IPC [2011/52]C12N15/11, A61K39/395, C12N5/10, C07K14/47, C07K16/30, C07K16/32, A61K48/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2016/18]
Former [2011/52]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  RO,  SE,  SI,  SK,  TR 
Extension statesAL15.10.2012
LT15.10.2012
LV15.10.2012
MK15.10.2012
TitleGerman:Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung[2011/52]
English:In tumours differentially expressed gene products and use of the same.[2015/35]
French:Produits géniques d'expression différentielle dans les tumeurs et leur utilisation[2011/52]
Former [2011/52]In tumours differentially expressed gene products and use of the same
Examination procedure15.10.2012Amendment by applicant (claims and/or description)
15.10.2012Examination requested  [2012/48]
02.10.2013Despatch of a communication from the examining division (Time limit: M06)
12.05.2014Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
23.06.2014Reply to a communication from the examining division
21.05.2015Despatch of a communication from the examining division (Time limit: M04)
02.06.2015Reply to a communication from the examining division
05.08.2015Despatch of a communication from the examining division (Time limit: M02)
02.09.2015Reply to a communication from the examining division
07.10.2015Communication of intention to grant the patent
13.10.2015Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
18.11.2015Communication of intention to grant the patent
15.03.2016Fee for grant paid
15.03.2016Fee for publishing/printing paid
15.03.2016Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP03773719.4  / EP1563068
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20030773719) is  08.09.2009
Opposition(s)07.02.2017No opposition filed within time limit [2017/15]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
23.06.2014Request for further processing filed
23.06.2014Full payment received (date of receipt of payment)
Request granted
01.07.2014Decision despatched
Fees paidRenewal fee
22.12.2011Renewal fee patent year 03
22.12.2011Renewal fee patent year 04
22.12.2011Renewal fee patent year 05
22.12.2011Renewal fee patent year 06
22.12.2011Renewal fee patent year 07
22.12.2011Renewal fee patent year 08
22.12.2011Renewal fee patent year 09
28.11.2012Renewal fee patent year 10
29.11.2013Renewal fee patent year 11
27.11.2014Renewal fee patent year 12
27.11.2015Renewal fee patent year 13
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Documents cited:Search[XI] WO0218576  (DIADEXUS INC et al.)
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DOI:   http://dx.doi.org/10.1128/MCB.21.21.7380-7390.2001
 [A]   REITER Y ET AL: "peptide-specific killing of antigen-presenting cells by a recombinant antibody-toxin fusion protein targeted to major histocompatibility complex/peptide class I complexes with T cell receptor-like specificity", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 94, April 1997 (1997-04-01), pages 4631 - 4636, XP002967291, ISSN: 0027-8424

DOI:   http://dx.doi.org/10.1073/pnas.94.9.4631
 [A]   ENGBERG J ET AL: "RECOMBINANT ANTIBODIES WITH THE ANTIGEN-SPECIFIC, MHC RESTRICTED SPECIFICITY OF T CELLS: NOVEL REAGENTS FOR BASIC AND CLINICAL INVESTIGATIONS AND IMMUNOTHERAPY", IMMUNOTECHNOLOGY, XX, XX, vol. 4, March 1999 (1999-03-01), pages 273 - 278, XP000991083

DOI:   http://dx.doi.org/10.1016/S1380-2933(98)00017-7
 [A]   RUDOLPH M G ET AL: "The specificity of TCR/pMHC interaction", CURRENT OPINION IN IMMUNOLOGY, CURRENT BIOLOGY LTD, vol. 14, no. 1, 1 February 2002 (2002-02-01), pages 52 - 65, XP004332735, ISSN: 0952-7915

DOI:   http://dx.doi.org/10.1016/S0952-7915(01)00298-9
 [A]   SPIRO R G: "PROTEIN GLYCOSYLATION: NATURE, DISTRIBUTION, ENZYMATIC FORMATION, AND DISEASE IMPLICATIONS OF GLYCOPEPTIDE BONDS", GLYCOBIOLOGY, OXFORD UNIVERSITY PRESS, US, vol. 12, no. 4, 1 January 2002 (2002-01-01), pages 43R - 56R, XP008034331, ISSN: 0959-6658, DOI: 10.1093/GLYCOB/12.4.43R

DOI:   http://dx.doi.org/10.1093/glycob/12.4.43R
Examination  Y SANADA ET AL: "Down-regulation of the claudin-18 gene, identified through serial analysis of gene expression data analysis, in gastric cancer with an intestinal phenotype", THE JOURNAL OF PATHOLOGY, vol. 208, no. 5, 1 April 2006 (2006-04-01), pages 633 - 642, XP055080460, ISSN: 0022-3417, DOI: 10.1002/path.1922

DOI:   http://dx.doi.org/10.1002/path.1922
   SAHIN UGUR ET AL: "Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development", CLINICAL CANCER RESEARCH, THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, vol. 14, no. 23, 1 December 2008 (2008-12-01), pages 7624 - 7634, XP002588324, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-08-1547

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-08-1547
   RIEMER A B ET AL: "Matching of trastuzumab (Herceptin<(>R)) epitope mimics onto the surface of Her-2/neu - a new method of epitope definition", MOLECULAR IMMUNOLOGY, PERGAMON, GB, vol. 42, no. 9, 1 May 2005 (2005-05-01), pages 1121 - 1124, XP027635008, ISSN: 0161-5890, [retrieved on 20050501]
   P BCHLER ET AL: "Therapy for pancreatic cancer with a recombinant humanized anti-HER2 antibody (herceptin)", JOURNAL OF GASTROINTESTINAL SURGERY, vol. 5, no. 2, 1 April 2001 (2001-04-01), pages 139 - 146, XP055188573, ISSN: 1091-255X, DOI: 10.1016/S1091-255X(01)80025-1

DOI:   http://dx.doi.org/10.1016/S1091-255X(01)80025-1
by applicantWO9204381
 WO9633265
 WO9633739
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