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Extract from the Register of European Patents

EP About this file: EP2599482

EP2599482 - Low dose therapeutic use of glyceryl tri-(4-phenylbutyrate) [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  20.06.2014
Database last updated on 17.05.2024
Most recent event   Tooltip20.06.2014Application deemed to be withdrawnpublished on 23.07.2014  [2014/30]
Applicant(s)For all designated states
Lunamed AG
Rabengasse 4
7000 Chur / CH
[2013/23]
Inventor(s)01 / Truog, Peter
Rabengasse 4
7000 Chur / CH
02 / Buschmann, Helmut H.
Sperberweg 15
52076 Aachen / DE
 [2013/23]
Representative(s)Peters, Hajo, et al
ZACCO GmbH
Bayerstrasse 83
80335 München / DE
[N/P]
Former [2013/23]Peters, Hajo, et al
ZACCO GmbH Bayerstrasse 83
80335 München / DE
Application number, filing date11009476.030.11.2011
[2013/23]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2599482
Date:05.06.2013
Language:EN
[2013/23]
Search report(s)(Supplementary) European search report - dispatched on:EP28.02.2012
ClassificationIPC:A61K31/192, A61K31/215, A61P25/28, A61P25/24, A61P25/00, A61P3/00, A61P9/00
[2013/23]
CPC:
A61K31/192 (EP); A61K31/198 (EP); A61K31/215 (EP);
A61K31/216 (EP); A61K45/06 (EP); A61P25/00 (EP);
A61P25/24 (EP); A61P25/28 (EP); A61P3/00 (EP);
A61P9/00 (EP) (-)
C-Set:
A61K31/198, A61K2300/00 (EP);
A61K31/216, A61K2300/00 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/23]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:Therapeutische Verwendung von niedrig dosiertem Glyceryl Tri-(4-Phenylbutyrat)[2013/23]
English:Low dose therapeutic use of glyceryl tri-(4-phenylbutyrate)[2013/23]
French:Application thérapeutique à faible dose de triglycéryl-(4-phénylbutyrate)[2013/23]
Examination procedure06.12.2013Application deemed to be withdrawn, date of legal effect  [2014/30]
13.01.2014Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2014/30]
Fees paidPenalty fee
Additional fee for renewal fee
30.11.201303   M06   Not yet paid
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Documents cited:Search[X]WO2005053607  (MEDICIS PHARMACEUTICAL CORP [US]) [X] 1-5,8,10-13,15 * claims 1, 3, 7, 11, 17, 21 * * page 8, paragraph 36 *;
 [I]EP1291015  (LUNAMED AG [CH]) [I] 1-15 * claims 1,4 * * columns 8,9; example 2 * * columns 1,2, paragraphs 4,5 *;
 [A]WO2010025303  (HYPERION THERAPEUTICS [US], et al) [A] 1-15 * the whole document *
 [X]  - T. KASUMOV, "NEW SECONDARY METABOLITES OF PHENYLBUTYRATE IN HUMANS AND RATS", DRUG METABOLISM AND DISPOSITION, (20040101), vol. 32, no. 1, doi:10.1124/dmd.32.1.10, ISSN 0090-9556, pages 10 - 19, XP055019599 [X] 1-4 * page 13, column l, paragraph 4 *

DOI:   http://dx.doi.org/10.1124/dmd.32.1.10
 [X]  - CHANG ET AL, "Synthesis of triglycerides of phenylalkanoic acids by lipase-catalyzed esterification in a solvent-free system", JOURNAL OF BIOTECHNOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (20061222), vol. 127, no. 4, doi:10.1016/J.JBIOTEC.2006.08.003, ISSN 0168-1656, pages 694 - 702, XP005810982 [X] 1-4 * page 697, column l, paragraph l * * page 701, column r *

DOI:   http://dx.doi.org/10.1016/j.jbiotec.2006.08.003
 [I]  - LEE B ET AL, "Phase 2 comparison of a novel ammonia scavenging agent with sodium phenylbutyrate in patients with urea cycle disorders: Safety, pharmacokinetics and ammonia control", MOLECULAR GENETICS AND METABOLISM, ACADEMIC PRESS, SAN DIEGO, CA, US, vol. 100, no. 3, doi:10.1016/J.YMGME.2010.03.014, ISSN 1096-7192, (20100701), pages 221 - 228, (20100605), XP027079433 [I] 1-15 * page 2, paragraphs 5,6 * * page 6 *

DOI:   http://dx.doi.org/10.1016/j.ymgme.2010.03.014
by applicantWO8504805
 DE19810383
 WO9307866
 WO9510271
 EP0725635
 WO9856370
 US6207195
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