Extract from the Register of European Patents

EP About this file: EP2555771

EP2555771 - PHARMACEUTICAL COMPOSITIONS STRONGLY DOSED IN BIOTINE [Right-click to bookmark this link]
Former [2013/07]PHARMACEUTICAL COMPOSITIONS HIGHLY DOSED WITH BIOTIN
[2016/37]
StatusNo opposition filed within time limit
Status updated on  29.09.2017
Database last updated on 31.03.2026
Most recent event   Tooltip29.09.2017No opposition filed within time limitpublished on 01.11.2017  [2017/44]
Applicant(s)For all designated states
Assistance Publique - Hôpitaux de Paris
3 Avenue Victoria
75004 Paris / FR
[2016/38]
Former [2013/07]For all designated states
Assistance Publique Hôpitaux De Paris
3 Avenue Victoria
75004 Paris / FR
Inventor(s)01 / SEDEL, Frédéric
17 rue des rigoles
F-75020 Paris / FR
02 / BELLANGER, Agnès
73 boulevard de Montparnasse
F-75006 Paris / FR
 [2013/07]
Representative(s)Flesselles, Bruno F.G.
BF IP
36 rue Jean de la Fontaine
75016 Paris / FR
[2016/47]
Former [2013/07]Flesselles, Bruno F.G.
Caninet BF IP 4, rue Ribera
75016 Paris / FR
Application number, filing date11714252.105.04.2011
[2016/47]
WO2011EP55273
Priority number, dateFR2010005258906.04.2010         Original published format: FR 1052589
[2013/07]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report
No.:WO2011124571
Date:13.10.2011
Language:FR
[2011/41]
Type: A1 Application with search report 
No.:EP2555771
Date:13.02.2013
Language:FR
The application published by WIPO in one of the EPO official languages on 13.10.2011 takes the place of the publication of the European patent application.
[2013/07]
Type: B1 Patent specification 
No.:EP2555771
Date:23.11.2016
Language:FR
[2016/47]
Search report(s)International search report - published on:EP13.10.2011
ClassificationIPC:A61K31/4188, A61P27/02
[2013/07]
CPC:
A61K31/4188 (EP,US); A61K31/407 (US); A61P27/00 (EP);
A61P27/02 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/07]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:PHARMAZEUTISCHE ZUSAMMENSETZUNGEN MIT HÖHER DOSIERUNG IN BIOTINE[2016/37]
English:PHARMACEUTICAL COMPOSITIONS STRONGLY DOSED IN BIOTINE[2016/37]
French:COMPOSITIONS PHARMACEUTIQUES FORTEMENT DOSEES EN BIOTINE[2013/07]
Former [2013/07]MIT BIOTIN HOCHDOSIERTE PHARMAZEUTISCHE ZUSAMMENSETZUNGEN
Former [2013/07]PHARMACEUTICAL COMPOSITIONS HIGHLY DOSED WITH BIOTIN
Entry into regional phase08.10.2012National basic fee paid 
08.10.2012Designation fee(s) paid 
08.10.2012Examination fee paid 
Examination procedure08.10.2012Examination requested  [2013/07]
06.06.2013Amendment by applicant (claims and/or description)
30.06.2015Despatch of a communication from the examining division (Time limit: M06)
04.01.2016Reply to a communication from the examining division
25.08.2016Communication of intention to grant the patent
17.10.2016Fee for grant paid
17.10.2016Fee for publishing/printing paid
17.10.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  30.06.2015
Opposition(s)24.08.2017No opposition filed within time limit [2017/44]
Fees paidRenewal fee
24.04.2013Renewal fee patent year 03
24.04.2014Renewal fee patent year 04
27.04.2015Renewal fee patent year 05
25.04.2016Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Licence(s)ID:01 01/exclusive
For:AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Licencee:MEDDAY
26 rue des Rigoles
75020 Paris / FR
Date:22.07.2014
[2014/37]
Lapses during opposition  Tooltipdeleted
[2017/13]
Former [2017/12]LV23.11.2016
Cited inInternational search[XA]   WEBER PETER ET AL: "Outcome in patients with profound biotinidase deficiency: relevance of newborn screening", DEVELOPMENTAL MEDICINE & CHILD NEUROLOGY, vol. 46, no. 7, July 2004 (2004-07-01), pages 481 - 484, XP008126454, ISSN: 0012-1622

DOI:   http://dx.doi.org/10.1111/j.1469-8749.2004.tb00509.x
 [X]   RAHMAN SHAMIMA ET AL: "Late presentation of biotinidase deficiency with acute visual loss and gait disturbance", DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, vol. 39, no. 12, December 1997 (1997-12-01), pages 830 - 831, XP008126455, ISSN: 0012-1622

DOI:   http://dx.doi.org/10.1111/j.1469-8749.1997.tb07552.x
 [X]   YANG YANLING ET AL: "Spinal cord demyelination associated with biotinidase deficiency in 3 Chinese patients", JOURNAL OF CHILD NEUROLOGY, vol. 22, no. 2, February 2007 (2007-02-01), pages 156 - 160, XP008126453, ISSN: 0883-0738

DOI:   http://dx.doi.org/10.1177/0883073807300307
 [A]   PUERTAS BORDALLO D ET AL: "[Optic neuropathy in biotinidase deficiency]", ARCHIVOS DE LA SOCIEDAD ESPAOLA DE OFTALMOLOGA AUG 2004 LNKD- PUBMED:15306966, vol. 79, no. 8, August 2004 (2004-08-01), pages 393 - 396, XP008126451, ISSN: 0365-6691
 [X]   DATABASE WPI Week 199724, Derwent World Patents Index; AN 1997-267712, XP002599161
by applicant  DABBAGH 0, BRISMAR J, GASCON GG, OZAND PT: "The clinical spectrum of biotin- treatable encephalopathies in Saudi Arabia", BRAIN DEV., vol. 16, 1994, pages 72 - 80, XP024397613, DOI: doi:10.1016/0387-7604(94)90099-X

DOI:   http://dx.doi.org/10.1016/0387-7604(94)90099-X
   DEBS R, DEPIENNE C, RASTETTER A, BELLANGER A, DEGOS B, GALANAUD D, KEREN B, LYON-CAEN 0, BRICE A, SEDEL F: "Biotin-Responsive Basal Ganglia Disease (BBGD) in Europeans with novel SLC19A3 mutations", ARCH NEUROL., vol. 67, no. 1, January 2010 (2010-01-01), pages 126 - 30
   OZAND PT, GASCON GG, AI ESSA M, JOSHI S, AI JISHI E, BAKHEET S, AI WATBAN J, AI-KAWI MZ, DABBAGH O: "Biotin-responsive basal ganglia disease: a novel entity", BRAIN., vol. 121, July 1998 (1998-07-01), pages 1267 - 79
   RAMAEKERS VT, BRAB M, RAU G, HEIMANN G.: "Recovery from neurological deficits following biotin treatment in a biotinidase Km variant", NEUROPEDIATRICS, vol. 24, 1993, pages 98 - 102, XP008126439, DOI: doi:10.1055/s-2008-1071522

DOI:   http://dx.doi.org/10.1055/s-2008-1071522
   SEDEL F, TOURBAH A, FONTAINE B, LUBETZKI C, BAUMANN N, SAUDUBRAY JM, LYON-CAEN O: "Leukoencephalopathies associated with Inborn Errors of Metabolism in adults: a diagnostic approach", J INHERIT METAB DIS., vol. 31, no. 3, June 2008 (2008-06-01), pages 295 - 307
   SUBRAMANIAN VS, MARCHANT JS, SAID HM: "Biotin-responsive basal ganglia disease- linked mutations inhibit thiamine transport via hTHTR2 : biotin is not a substrate for hTHTR2", AM J PHYSIOL., vol. 291, no. 5, 2006, pages 851 - 859
   VLASOVA TI, STRATTON SL, WELLS AM, MOCK NI, MOCK DM: "Biotin deficiency reduces expression of SLC19A3, a potential biotin transporter, in leukocytes from human blood", J NUTR., vol. 135, no. 1, 2005, pages 42 - 47
   WOLF B, POMPONIO RJ, NORRGARD KJ, LOTT IT, BAUMGARTNER ER, SUORMALA T, RAMAEKERS VT, COSKUN T, TOKATLI A, OZALP, J PEDIATR., vol. 132, no. 2, 1998, pages 362 - 5
   ZEMPLENI J, WIJERATNE SS, HASSAN YI, BIOTIN. BIOFACTORS, vol. 35, no. 1, 2009, pages 36 - 46
   ZENG WQ, AI-YAMANI E, ACIERNO JS JR ET AL.: "Biotin-responsive basal ganglia diease maps to 2q36.3 and is due to mutations in SCL19A3", AM J HUM GENET, vol. 77, no. 1, 2005, pages 16 - 26
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.