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EP2841437
European procedure
Extract from the Register of European Patents
EP About this file: EP2841437
| EP2841437 - IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 11.05.2018 Database last updated on 01.04.2026 | |
| Former | The patent has been granted Status updated on 02.06.2017 | ||
| Former | Grant of patent is intended Status updated on 19.01.2017 | Most recent event Tooltip | 11.05.2018 | No opposition filed within time limit | published on 13.06.2018 [2018/24] | Applicant(s) | For all designated states Bristol-Myers Squibb Company Route 206 and Province Line Road Princeton, NJ 08543 / US | For all designated states Université de Montréal 2900 Boulevard Edouard-Montpetit Montreal, QC H3T 1J4 / CA | [2015/10] | Inventor(s) | 01 /
BANVILLE, Jacques c/o Université de Montréal 2900 Édouard-Montpetit Boulevard Montréal, Québec H3T 1J4 / CA | 02 /
RÉMILLARD, Roger 13 Des cèdres Avenue Napierville, Québec J0J 1L0 / CA | 03 /
RUEDIGER, Edward H. c/o Université de Montréal 2900 Édouard-Montpetit Boulevard Montréal, Québec H3T 1J4 / CA | 04 /
DEON, Daniel H. c/o Université de Montréal 2900 Édouard-Montpetit Boulevard Montréal, Québec H3T 1J4 / CA | 05 /
GAGNON, Marc c/o Université de Montréal 2900 Édouard-Montpetit Boulevard Montréal, Québec H3T 1J4 / CA | 06 /
DUBÉ, Laurence c/o Université de Montréal 2900 Édouard-Montpetit Boulevard Montréal, Québec H3T 1J4 / CA | 07 /
GUY, Julia c/o Université de Montréal 2900 Édouard-Montpetit Boulevard Montréal, Québec H3T 1J4 / CA | 08 /
PRIESTLEY, Eldon Scott c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road Pennington, New Jersey 08534 / US | 09 /
POSY, Shoshana L. c/o Bristol-Myers Squibb Company Route 206 and Province Line Road Pennington, New Jersey 08543 / US | 10 /
MAXWELL, Brad D. c/o Bristol-Myers Squibb Company Route 206 and Province Line Road Pennington, New Jersey 08543 / US | 11 /
WONG, Pancras C. c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road Pennington, New Jersey 08534 / US | 12 /
LAWRENCE, Michael, R. c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road Pennington, NJ 08534 / US | 13 /
MILLER, Michael, M. c/o Bristol-Myers Squibb Company Route 206 and Province Line Road Princeton, NJ 08543 / US | [2015/10] | Representative(s) | Beacham, Annabel Rose Dehns St Bride's House 10 Salisbury Square London EC4Y 8JD / GB | [2015/10] | Application number, filing date | 13721857.4 | 24.04.2013 | [2017/27] | WO2013US37956 | Priority number, date | US201261638577P | 26.04.2012 Original published format: US 201261638577 P | US201361787680P | 15.03.2013 Original published format: US 201361787680 P | [2015/10] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2013163279 | Date: | 31.10.2013 | Language: | EN | [2013/44] | Type: | A1 Application with search report | No.: | EP2841437 | Date: | 04.03.2015 | Language: | EN | The application published by WIPO in one of the EPO official languages on 31.10.2013 takes the place of the publication of the European patent application. | [2015/10] | Type: | B1 Patent specification | No.: | EP2841437 | Date: | 05.07.2017 | Language: | EN | [2017/27] | Search report(s) | International search report - published on: | EP | 31.10.2013 | Classification | IPC: | C07D519/00, A61K31/433, C07D513/04, A61K31/5025, C07D487/04, A61K31/4355, A61P7/02 | [2015/10] | CPC: |
C07D487/04 (EP,CN,KR,US);
C07D513/04 (EP,CN,KR,US);
A61K31/433 (EP,KR,US);
A61K31/435 (EP,US);
A61K31/4355 (KR);
A61K31/4439 (EP,US);
A61K31/454 (EP,US);
A61K31/496 (EP,US);
A61K31/497 (EP,US);
A61K31/5025 (EP,KR,US);
A61K31/5377 (EP,US);
A61K31/5386 (EP,US);
A61K31/541 (EP,US);
A61K31/55 (EP,US);
A61K31/553 (EP,US);
A61K45/06 (EP,US);
A61K51/0453 (US);
A61P43/00 (EP);
A61P7/00 (EP);
A61P7/02 (EP);
A61P9/00 (EP);
A61P9/10 (EP);
C07B59/002 (US);
C07D519/00 (EP,CN,US);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2015/10] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | IMIDAZOTHIADIAZOL- UND IMIDAZOPYRAZINDERIVATE ALS PROTEASEAKTIVIERTE REZEPTOR 4 (PAR4)-INHIBITOREN ZUR BEHANDLUNG VON THROMBOZYTENAGGREGATION | [2015/10] | English: | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | [2015/10] | French: | DÉRIVÉS D'IMIDAZOTHIADIAZOLE ET D'IMIDAZOPYRAZINE UTILISÉS COMME INHIBITEURS DU RÉCEPTEUR 4 ACTIVÉ PAR UNE PROTÉASE (PAR4) POUR LE TRAITEMENT DE L'AGRÉGATION PLAQUETTAIRE | [2015/10] | Entry into regional phase | 16.10.2014 | National basic fee paid | 16.10.2014 | Designation fee(s) paid | 16.10.2014 | Examination fee paid | Examination procedure | 16.10.2014 | Examination requested [2015/10] | 13.08.2015 | Amendment by applicant (claims and/or description) | 07.01.2016 | Despatch of a communication from the examining division (Time limit: M04) | 26.04.2016 | Reply to a communication from the examining division | 20.01.2017 | Communication of intention to grant the patent | 26.05.2017 | Fee for grant paid | 26.05.2017 | Fee for publishing/printing paid | 26.05.2017 | Receipt of the translation of the claim(s) | Divisional application(s) | EP17172927.0 / EP3243826 | EP19192142.8 / EP3632919 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 07.01.2016 | Opposition(s) | 06.04.2018 | No opposition filed within time limit [2018/24] | Fees paid | Renewal fee | 10.04.2015 | Renewal fee patent year 03 | 11.04.2016 | Renewal fee patent year 04 | 10.04.2017 | Renewal fee patent year 05 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [X] EP0005783 (BAYER AG et al.) | [X] WO2011074658 (MITSUBISHI TANABE PHARMA CORP et al.) | [X] EP2518066 (MITSUBISHI TANABE PHARMA CORP et al.) | [X] EP0185345 (THOMAE GMBH DR K et al.) | by applicant | EP1166785 | EP0667345 | US2005096362 | COUGHLIN, S.R., NATURE, vol. 407, 2000, pages 258 - 264 [X] 1,2,5,9 * the whole document * | TRICOCI, P. ET AL., N. ENG. J. MED., vol. 366, no. 1, 2012, pages 20 - 33 [X] 1,2 * the whole document * | LCC, F-Y. ET AL.: "Synthesis of 1-Benzyl-3-(5'-hydroxymethyl-2'-furyl)indazole Analogues as Novel Antiplatelet Agents", J. MED. CHEM., vol. 44, no. 22, 2001, pages 3746 - 3749, XP002239593, DOI: doi:10.1021/jm010001h DOI: http://dx.doi.org/10.1021/jm010001h | WU, C-C. ET AL.: "Selective Inhibition of Protease-activated Receptor 4-dependent Platelet Activation by YD-3", THROMB. HAEMOST., vol. 87, 2002, pages 1026 - 1033 | CHEN, H.S. ET AL.: "Synthesis and platelet activity", J. BIOORG. MED. CHEM., vol. 16, 2008, pages 1262 - 1278 | "Hawley's Condensed Chemical Dictionary", 1997, JOHN WILEY & SONS, INC. | "Remington: The Science and Practice Qf Pharmacy", 2012, PHARMACEUTICAL PRESS | "Design of Prodrugs", 1985, ELSEVIER | "Methods in Enzymology", vol. 112, 1985, ACADEMIC PRESS, pages: 309 - 396 | BUNDGAARD, H. ET AL.: "A Textbook of Drug Design and Development", 1991, HARWOOD ACADEMIC PUBLISHERS, article "Design and Application of Prodrugs", pages: 113 - 191 | BUNDGAARD, H., ADV. DRUG DELIV. REV., vol. 8, 1992, pages 1 - 38 | BUNDGAARD, H., J. PHARM. SCI., vol. 77, 1988, pages 285 | KAKEYA, N. ET AL., CHEM. PHARM. BULL., vol. 32, 1984, pages 692 | "Methods and Principles in Medicinal Chemistry", vol. 47, 2011, WILEY-VCH, article "Prodrugs and Targeted Delivery" | "Medicinal Chemistry: Principles and Practice", 2006, THE ROYAL SOCIETY OF CHEMISTRY | TESTA, B. ET AL.: "Hydrolysis in Drug and Prodrug Metabolism. Chemistry, Biochemistry and Enzymology", 2003, VCHA AND WILEY-VCH | "The Practice of Medicinal Chemistry", 2008, ACADEMIC PRESS | WUTS ET AL.: "Greene's Protective Groups In Organic Synthesis", 2006, WILEY-INTERSCIENCE | KAMISUKI, S. ET AL., TETRAHEDRON, vol. 60, 2004, pages 5695 - 5700 |