Extract from the Register of European Patents

EP About this file: EP2906252

EP2906252 - PYRROLOBENZODIAZEPINE-ANTI-HER2 ANTIBODY CONJUGATES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  20.04.2018
Database last updated on 16.05.2026
FormerThe patent has been granted
Status updated on  12.05.2017
FormerGrant of patent is intended
Status updated on  22.12.2016
Most recent event   Tooltip20.04.2018No opposition filed within time limitpublished on 23.05.2018  [2018/21]
Applicant(s)For all designated states
ADC Therapeutics SA
Route de la Corniche 3B
1066 Epalinges / CH
For all designated states
Medimmune Limited
Milstein Building Granta Park
Cambridge, Cambridgeshire CB21 6GH / GB
[2017/24]
Former [2017/11]For all designated states
ADC Therapeutics SA
route de la Corniche 3B
1066 Epalinges / CH
For all designated states
Medimmune Limited
Milstein Building Granta Park
Cambridge, Cambridgeshire CB21 6GH / GB
Former [2015/34]For all designated states
ADC Therapeutics S.a.r.l.
Rue Saint-Pierre 2
1003 Lausanne / CH
For all designated states
Medimmune Limited
Milstein Building Granta Park
Cambridge, Cambridgeshire CB21 6GH / GB
Inventor(s)01 / VAN BERKEL, Patricius Hendrikus Cornelis
ADC Therapeutics Sàrl
Rue Saint-Pierre 2
C/O Michael Forer
1003 Lausanne / CH
02 / HOWARD, Philip Wilson
Spirogen Limited The QMB Innovation Centre
42 New Road
London Greater London E1 2AX / GB
 [2015/34]
Representative(s)Watson, Robert James, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
[2015/34]
Application number, filing date13788691.711.10.2013
[2015/34]
WO2013EP71343
Priority number, dateUS201261712924P12.10.2012         Original published format: US 201261712924 P
US201261712928P12.10.2012         Original published format: US 201261712928 P
US201361784270P14.03.2013         Original published format: US 201361784270 P
US201361784233P14.03.2013         Original published format: US 201361784233 P
US201361784249P14.03.2013         Original published format: US 201361784249 P
[2015/34]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014057115
Date:17.04.2014
Language:EN
[2014/16]
Type: A1 Application with search report 
No.:EP2906252
Date:19.08.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 17.04.2014 takes the place of the publication of the European patent application.
[2015/34]
Type: B1 Patent specification 
No.:EP2906252
Date:14.06.2017
Language:EN
[2017/24]
Search report(s)International search report - published on:EP17.04.2014
ClassificationIPC:A61K47/68, A61P35/00, // C07K16/32, A61K39/395, A61K31/551
[2017/24]
CPC:
C07K16/32 (EP,US); A61K31/551 (EP,US); A61K47/6801 (EP,US);
A61K47/6855 (EP,US); A61P35/00 (EP); A61P43/00 (EP);
A61K2039/505 (EP,US) (-)
Former IPC [2017/01]A61K47/48, A61P35/00, // C07K16/32, A61K39/395, A61K31/551
Former IPC [2015/34]A61K47/48, A61P35/00, C07K16/30, A61K39/395, A61K31/551
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/34]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:PYRROLOBENZODIAZEPIN-ANTI-HER2-ANTIKÖRPERKONJUGATE[2015/34]
English:PYRROLOBENZODIAZEPINE-ANTI-HER2 ANTIBODY CONJUGATES[2015/34]
French:CONJUGUÉS ANTICORPS ANTI-HER2 - PYRROLOBENZODIAZÉPINE[2015/34]
Entry into regional phase06.05.2015National basic fee paid 
06.05.2015Designation fee(s) paid 
06.05.2015Examination fee paid 
Examination procedure06.05.2015Amendment by applicant (claims and/or description)
06.05.2015Examination requested  [2015/34]
01.04.2016Despatch of a communication from the examining division (Time limit: M06)
27.09.2016Reply to a communication from the examining division
23.12.2016Communication of intention to grant the patent
27.04.2017Fee for grant paid
27.04.2017Fee for publishing/printing paid
27.04.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  01.04.2016
Opposition(s)15.03.2018No opposition filed within time limit [2018/21]
Fees paidRenewal fee
26.10.2015Renewal fee patent year 03
24.10.2016Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[YDA] WO2011130598  (SPIROGEN LTD et al.) [YD] 1-99,101-116 * page 149; compound 80 * * pages 193-194; table 1; compounds 105,106,114,115 * * page 197, line 17 - page 200, line 24 * * figures 1a,1b; compounds 15ba, 15bb,15d, 58 * * figures 2-5 * * claim - *[A] 100
 [YDA] WO2011130613  (SEATTLE GENETICS INC et al.) [YD] 1-99,101-116 * page 50, line 29 * * page 90; compound 30 * * page 105; compound 51 *[A] 100
 [YDA] WO2011130616  (SPIROGEN LTD et al.) [YD] 1-99,101-116 * page 50, line 28 * * page 87; compound 26 * * page 89; compound 30 * * page 90; compound 31 *[A] 100
 [YA] WO2011137245  (ESPERANCE PHARMACEUTICALS INC et al.) [Y] 1-99,101,102,105-116 * paragraph [0063]; sequence VH * * paragraph [0064]; sequence VL * * paragraph [0065] *[A] 100
 [YA] US2008112961  (STAVENHAGEN JEFFREY B et al.) [Y] 1-99,102,105-116 * paragraph [0309] * * sequence 34 *[A] 100
 [YA] WO2010151793  (FIVE PRIME THERAPEUTICS INC et al.) [Y] 1-99,101-116 * example 1; sequences 2,5 *[A] 100
 [YPA] WO2013055987  (SPIROGEN SARL et al.) [YP] 1-99,101-116 * page 84; compound 14 * * page 88; compound 22 * * page 93; compounds 101,102,104,110,111 * * page 95, line 1 - page 97, line 5 * * figures 1,2 *[A] 100
 [AP] WO2012153193  (LEGOCHEM BIOSCIENCES INC et al.) [AP] 1-116 * page 62, compound LCB14-0577 * * page 66, compound LCB14-0578 * * page 68, compound LCB14-0582 * * page 71, compound LCB14-0594 * * page 73, compound LCB14-0596 * * page 77, compound LCB14-0597 * * page 79, compound LCB14-0599 * * example 1.1 *
 [T] WO2013177481  (IMMUNOGEN INC et al.) [T] 1-116 * page 71, line 23 * * page 95, formula at the bottom * * page 96, formula at the top *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.