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Extract from the Register of European Patents

EP About this file: EP2896628

EP2896628 - Process for efficient purification of neutral human milk oligosaccharides (HMOs) from microbial fermentation [Right-click to bookmark this link]
StatusThe patent has been granted
Status updated on  17.08.2018
Database last updated on 24.04.2024
FormerGrant of patent is intended
Status updated on  13.06.2018
FormerExamination is in progress
Status updated on  21.03.2017
Most recent event   Tooltip15.11.2023Change: Date of oral proceedings 
15.11.2023Deletion: Despatch of minutes of oral proceedings 
Applicant(s)For all designated states
Chr. Hansen HMO GmbH
Maarweg 32
53619 Rheinbreitbach / DE
[2021/25]
Former [2015/30]For all designated states
Jennewein Biotechnologie GmbH
Maarweg 32
53619 Rheinbreitbach / DE
Inventor(s)01 / Jennewein, Dr. Stefan
Wichfriedweg 14
53604 Bad Honnef / DE
 [2015/30]
Representative(s)HGF
HGF Limited
1 City Walk
Leeds LS11 9DX / GB
[N/P]
Former [2018/38]Pfenning, Meinig & Partner mbB
Patent- und Rechtsanwälte
Theresienhöhe 11a
80339 München / DE
Former [2015/30]Pfenning, Meinig & Partner GbR
Patent- und Rechtsanwälte
Theresienhöhe 11a
80339 München / DE
Application number, filing date14151737.520.01.2014
[2015/30]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2896628
Date:22.07.2015
Language:EN
[2015/30]
Type: B1 Patent specification 
No.:EP2896628
Date:19.09.2018
Language:EN
[2018/38]
Search report(s)(Supplementary) European search report - dispatched on:EP18.12.2014
ClassificationIPC:C07H1/08, C07H3/06, A23L29/30, A23L33/00, A23L33/21, A61K31/702, C12P19/14, A23L5/00
[2018/23]
CPC:
C07H1/08 (EP,CN,CZ,DK,KR,US); C07H3/06 (EP,AT,CN,CZ,DK,KR,US); C12N1/20 (RU);
A61K31/702 (EP,AT,CZ,DK,US); A23K20/163 (KR); A23L29/30 (EP,DK,KR,US);
A23L33/00 (DK); A23L33/21 (EP,DK,KR,US); A23L33/40 (EP,AT,KR,US);
A23L5/00 (EP,DK,US); A61P1/00 (EP,CZ); A61P1/04 (EP);
A61P1/14 (AT); C07H1/06 (RU); C12P19/00 (RU);
C12P19/14 (DK,US); A23V2002/00 (US); Y02A50/30 (EP) (-)
Former IPC [2015/30]C07H1/08, C07H3/06, A23L1/308
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/10]
Former [2015/30]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
TitleGerman:Verfahren zur effizienten Reinigung von neutralen humanen Milch-Oligosacchariden (HMOs) aus mikrobieller Fermentation[2015/30]
English:Process for efficient purification of neutral human milk oligosaccharides (HMOs) from microbial fermentation[2015/30]
French:Procédé permettant de purifier efficacement des oligosaccharides du lait humain neutre (HMO) à partir de la fermentation microbienne[2015/30]
Examination procedure22.01.2016Amendment by applicant (claims and/or description)
22.01.2016Examination requested  [2016/10]
08.04.2016Despatch of a communication from the examining division (Time limit: M06)
10.10.2016Reply to a communication from the examining division
10.03.2017Despatch of a communication from the examining division (Time limit: M04)
03.05.2017Observations by third parties
13.07.2017Reply to a communication from the examining division
26.09.2017Observations by third parties
26.04.2018Date of oral proceedings
04.06.2018Minutes of oral proceedings despatched
14.06.2018Communication of intention to grant the patent
09.08.2018Fee for grant paid
09.08.2018Fee for publishing/printing paid
09.08.2018Receipt of the translation of the claim(s)
05.11.2018Observations by third parties
22.10.2019Observations by third parties
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  08.04.2016
Opposition(s)Opponent(s)01  12.06.2019  24.06.2019  ADMISSIBLE
FrieslandCampina Nederland B.V.
Stationsplein 4
3818 LE Amersfoort / NL
Opponent's representative
FrieslandCampina IP Department
Bronland 20
6708 WH Wageningen / NL
 02  18.06.2019  26.06.2019  ADMISSIBLE
Greaves Brewster LLP
Copa House
Station Road
Cheddar
Somerset BS27 3AH / GB
 03  18.06.2019  24.06.2019  WITHDRAWN
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
 04  19.06.2019  27.09.2021  WITHDRAWN
Glycom A/S
Kogle Allé 4
2970 Hørsholm / DK
Opponent's representative
Strych, Sebastian, et al, et al
Mitscherlich PartmbB
Patent- und Rechtsanwälte
Karlstraße 7
80333 München / DE
 05  19.06.2019  26.06.2019  ADMISSIBLE
BASF SE
Carl-Bosch-Str. 38
67056 Ludwigshafen am Rhein / DE
Opponent's representative
Altmann Stößel Dick Patentanwälte PartG mbB
Theodor-Heuss-Anlage 2
68165 Mannheim / DE
 06  23.04.2020  20.05.2021  WITHDRAWN
Nestlé Deutschland AG
Lyoner Str. 23
60528 Frankfurt am Main / DE
Opponent's representative
Alt, Michael
Bird & Bird LLP
Maximiliansplatz 22
80333 München / DE
 [N/P]
Former [2022/03]
Opponent(s)01  12.06.2019  24.06.2019  ADMISSIBLE
FrieslandCampina Nederland B.V.
Stationsplein 4
3818 LE Amersfoort / NL
Opponent's representative
FrieslandCampina Nederland B.V.
IP Department
Bronland 20
6708 WH Wageningen / NL
 02  18.06.2019  26.06.2019  ADMISSIBLE
Greaves Brewster LLP
Copa House
Station Road
Cheddar
Somerset BS27 3AH / GB
 03  18.06.2019  24.06.2019  WITHDRAWN
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
 04  19.06.2019  27.09.2021  WITHDRAWN
Glycom A/S
Kogle Allé 4
2970 Hørsholm / DK
Opponent's representative
Strych, Sebastian, et al, et al
Mitscherlich PartmbB
Patent- und Rechtsanwälte
Sonnenstraße 33
80331 München / DE
 05  19.06.2019  26.06.2019  ADMISSIBLE
BASF SE
Carl-Bosch-Str. 38
67056 Ludwigshafen am Rhein / DE
Opponent's representative
Altmann Stößel Dick Patentanwälte PartG mbB
Theodor-Heuss-Anlage 2
68165 Mannheim / DE
 06  23.04.2020  20.05.2021  WITHDRAWN
Nestlé Deutschland AG
Lyoner Str. 23
60528 Frankfurt am Main / DE
Opponent's representative
Alt, Michael
Bird & Bird LLP
Maximiliansplatz 22
80333 München / DE
Former [2021/44]
Opponent(s)01  12.06.2019  24.06.2019  ADMISSIBLE
FrieslandCampina Nederland B.V.
Stationsplein 4
3818 LE Amersfoort / NL
Opponent's representative
FrieslandCampina Nederland B.V.
IP Department
Bronland 20
6708 WH Wageningen / NL
 02  18.06.2019  26.06.2019  ADMISSIBLE
Greaves Brewster LLP
Copa House
Station Road
Cheddar
Somerset BS27 3AH / GB
 03  18.06.2019  24.06.2019  ADMISSIBLE
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
 04  19.06.2019  27.09.2021  WITHDRAWN
Glycom A/S
Kogle Allé 4
2970 Hørsholm / DK
Opponent's representative
Strych, Sebastian, et al, et al
Mitscherlich PartmbB
Patent- und Rechtsanwälte
Sonnenstraße 33
80331 München / DE
 05  19.06.2019  26.06.2019  ADMISSIBLE
BASF SE
Carl-Bosch-Str. 38
67056 Ludwigshafen am Rhein / DE
Opponent's representative
Altmann Stößel Dick Patentanwälte PartG mbB
Theodor-Heuss-Anlage 2
68165 Mannheim / DE
 06  23.04.2020  20.05.2021  WITHDRAWN
Nestlé Deutschland AG
Lyoner Str. 23
60528 Frankfurt am Main / DE
Opponent's representative
Alt, Michael
Bird & Bird LLP
Maximiliansplatz 22
80333 München / DE
Former [2021/26]
Opponent(s)01  12.06.2019  24.06.2019  ADMISSIBLE
FrieslandCampina Nederland B.V.
Stationsplein 4
3818 LE Amersfoort / NL
Opponent's representative
FrieslandCampina Nederland B.V.
IP Department
Bronland 20
6708 WH Wageningen / NL
 02  18.06.2019  26.06.2019  ADMISSIBLE
Greaves Brewster LLP
Copa House
Station Road
Cheddar
Somerset BS27 3AH / GB
 03  18.06.2019  24.06.2019  ADMISSIBLE
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
 04  19.06.2019  26.06.2019  ADMISSIBLE
Glycom A/S
Kogle Allé 4
2970 Hørsholm / DK
Opponent's representative
Strych, Sebastian, et al, et al
Mitscherlich PartmbB
Patent- und Rechtsanwälte
Sonnenstraße 33
80331 München / DE
 05  19.06.2019  26.06.2019  ADMISSIBLE
BASF SE
Carl-Bosch-Str. 38
67056 Ludwigshafen am Rhein / DE
Opponent's representative
Altmann Stößel Dick Patentanwälte PartG mbB
Dudenstrasse 46
68167 Mannheim / DE
 06  23.04.2020  20.05.2021  WITHDRAWN
Nestlé Deutschland AG
Lyoner Str. 23
60528 Frankfurt am Main / DE
Opponent's representative
Alt, Michael
Bird & Bird LLP
Maximiliansplatz 22
80333 München / DE
Former [2020/44]
Opponent(s)01  12.06.2019  24.06.2019  ADMISSIBLE
FrieslandCampina Nederland B.V.
Stationsplein 4
3818 LE Amersfoort / NL
Opponent's representative
FrieslandCampina Nederland B.V.
IP Department
Bronland 20
6708 WH Wageningen / NL
 02  18.06.2019  26.06.2019  ADMISSIBLE
Greaves Brewster LLP
Copa House
Station Road
Cheddar
Somerset BS27 3AH / GB
 03  18.06.2019  24.06.2019  ADMISSIBLE
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
 04  19.06.2019  26.06.2019  ADMISSIBLE
Glycom A/S
Kogle Allé 4
2970 Hørsholm / DK
Opponent's representative
Strych, Sebastian, et al, et al
Mitscherlich PartmbB
Patent- und Rechtsanwälte
Sonnenstraße 33
80331 München / DE
 05  19.06.2019  26.06.2019  ADMISSIBLE
BASF SE
Carl-Bosch-Str. 38
67056 Ludwigshafen am Rhein / DE
Opponent's representative
Altmann Stößel Dick Patentanwälte PartG mbB
Dudenstrasse 46
68167 Mannheim / DE
 06  23.04.2020  27.04.2020  INTERVENTION ADMISSIBLE
Nestlé Deutschland AG
Lyoner Str. 23
60528 Frankfurt am Main / DE
Opponent's representative
Alt, Michael
Bird & Bird LLP
Maximiliansplatz 22
80333 München / DE
Former [2020/23]
Opponent(s)01  12.06.2019  24.06.2019  ADMISSIBLE
FrieslandCampina Nederland B.V.
Stationsplein 4
3818 LE Amersfoort / NL
Opponent's representative
FrieslandCampina Nederland B.V.
IP Department
Bronland 20
6708 WH Wageningen / NL
 02  18.06.2019  26.06.2019  ADMISSIBLE
Greaves Brewster LLP
Copa House
Station Road
Cheddar
Somerset BS27 3AH / GB
 03  18.06.2019  24.06.2019  ADMISSIBLE
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
 04  19.06.2019  26.06.2019  ADMISSIBLE
Glycom A/S
Kogle Allé 4
2970 Hørsholm / DK
Opponent's representative
Rupp, Christian
Mitscherlich PartmbB
Patent- und Rechtsanwälte
Sonnenstraße 33
80331 München / DE
 05  19.06.2019  26.06.2019  ADMISSIBLE
BASF SE
Carl-Bosch-Str. 38
67056 Ludwigshafen am Rhein / DE
Opponent's representative
Altmann Stößel Dick Patentanwälte PartG mbB
Dudenstrasse 46
68167 Mannheim / DE
 06  23.04.2020  27.04.2020  INTERVENTION ADMISSIBLE
Nestlé Deutschland AG
Lyoner Str. 23
60528 Frankfurt am Main / DE
Opponent's representative
Alt, Michael
Bird & Bird LLP
Maximiliansplatz 22
80333 München / DE
Former [2020/19]
Opponent(s)01  12.06.2019  24.06.2019  ADMISSIBLE
FrieslandCampina Nederland B.V.
Stationsplein 4
3818 LE Amersfoort / NL
Opponent's representative
FrieslandCampina Nederland B.V.
IP Department
Bronland 20
6708 WH Wageningen / NL
 02  18.06.2019  26.06.2019  ADMISSIBLE
Greaves Brewster LLP
Copa House
Station Road
Cheddar
Somerset BS27 3AH / GB
 03  18.06.2019  24.06.2019  ADMISSIBLE
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
 04  19.06.2019  26.06.2019  ADMISSIBLE
Glycom A/S
Kogle Allé 4
2970 Hørsholm / DK
Opponent's representative
Rupp, Christian
Mitscherlich PartmbB
Patent- und Rechtsanwälte
Sonnenstraße 33
80331 München / DE
 05  19.06.2019  26.06.2019  ADMISSIBLE
BASF SE
Carl-Bosch-Str. 38
67056 Ludwigshafen am Rhein / DE
Opponent's representative
Altmann Stößel Dick Patentanwälte PartG mbB
Dudenstrasse 46
68167 Mannheim / DE
Former [2019/31]
Opponent(s)01  12.06.2019  24.06.2019  ADMISSIBLE
FrieslandCampina Nederland B.V.
Stationsplein 4
3818 LE Amersfoort / NL
Opponent's representative
FrieslandCampina Nederland B.V.
IP Department
Bronland 20
6708 WH Wageningen / NL
 02  18.06.2019  26.06.2019  ADMISSIBLE
Greaves Brewster LLP
Copa House
Station Road
Cheddar
Somerset BS27 3AH / GB
 03  18.06.2019  24.06.2019  ADMISSIBLE
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
 04  19.06.2019  26.06.2019  ADMISSIBLE
Glycom A/S
Kogle Allé 4
2970 Hørsholm / DK
Opponent's representative
AWA Denmark A/S
Strandgade 56
1401 Copenhagen K / DK
 05  19.06.2019  26.06.2019  ADMISSIBLE
BASF SE
Carl-Bosch-Str. 38
67056 Ludwigshafen am Rhein / DE
Opponent's representative
Herzog, Fiesser & Partner Patentanwälte PartG mbB
Dudenstrasse 46
68167 Mannheim / DE
Former [2019/29]
Opponent(s)01  12.06.2019    ADMISSIBLE
FrieslandCampina Nederland B.V.
Stationsplein 4
3818 LE Amersfoort / NL
Opponent's representative
FrieslandCampina Nederland B.V.
IP Department
Bronland 20
6708 WH Wageningen / NL
08.07.2019Invitation to proprietor to file observations on the notice of opposition
17.01.2020Reply of patent proprietor to notice(s) of opposition
08.09.2020Cancellation of oral proceeding that was planned for 19.11.2020
19.11.2020Date of oral proceedings
12.07.2021Date of oral proceedings
25.08.2021Despatch of minutes of oral proceedings
25.08.2021Despatch of communication that the patent will be revoked
Appeal following opposition25.10.2021Appeal received No.  T1945/21
22.10.2021Payment of appeal fee
22.12.2021Statement of grounds filed
19.09.2024Date of oral proceedings
Fees paidRenewal fee
29.01.2016Renewal fee patent year 03
30.01.2017Renewal fee patent year 04
30.01.2018Renewal fee patent year 05
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Lapses during opposition  TooltipHU20.01.2014
AL19.09.2018
CY19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
MK19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SI19.09.2018
SM19.09.2018
TR19.09.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
LU20.01.2019
MT20.01.2019
[2022/31]
Former [2021/32]HU20.01.2014
AL19.09.2018
CY19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SI19.09.2018
SM19.09.2018
TR19.09.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
LU20.01.2019
MT20.01.2019
Former [2021/26]AL19.09.2018
CY19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SI19.09.2018
SM19.09.2018
TR19.09.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
LU20.01.2019
MT20.01.2019
Former [2020/29]AL19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SI19.09.2018
SM19.09.2018
TR19.09.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
LU20.01.2019
MT20.01.2019
Former [2020/17]AL19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SI19.09.2018
SM19.09.2018
TR19.09.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
LU20.01.2019
Former [2019/50]AL19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SI19.09.2018
SM19.09.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
LU20.01.2019
Former [2019/44]AL19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SM19.09.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
LU20.01.2019
Former [2019/40]AL19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SM19.09.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
Former [2019/26]AL19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SM19.09.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
Former [2019/24]AL19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
GR20.12.2018
IS19.01.2019
Former [2019/22]AL19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
GR20.12.2018
IS19.01.2019
Former [2019/21]AL19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
RS19.09.2018
SE19.09.2018
GR20.12.2018
IS19.01.2019
Former [2019/12]AL19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
RS19.09.2018
SE19.09.2018
GR20.12.2018
Former [2019/11]FI19.09.2018
HR19.09.2018
LT19.09.2018
RS19.09.2018
SE19.09.2018
GR20.12.2018
Former [2019/10]FI19.09.2018
LT19.09.2018
RS19.09.2018
SE19.09.2018
GR20.12.2018
Former [2019/08]FI19.09.2018
LT19.09.2018
Former [2019/07]LT19.09.2018
Documents cited:Search[Y]EP2479263  (JENNEWEIN BIOTECHNOLOGIE GMBH [DE]) [Y] 1-12 * page 10, paragraph 98 - page 11, paragraph 103 ** paragraph [0052] *;
 [Y]  - ALBERMANN C ET AL, "Synthesis of the milk oligosaccharide 2'-fucosyllactose using recombinant bacterial enzymes", CARBOHYDRATE RESEARCH, PERGAMON, GB, (20010823), vol. 334, no. 2, doi:10.1016/S0008-6215(01)00177-X, ISSN 0008-6215, pages 97 - 103, XP004298614 [Y] 1-12 * page 102, paragraph 1 - column 2 *

DOI:   http://dx.doi.org/10.1016/S0008-6215(01)00177-X
ExaminationWO2012092160
 WO2012112777
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 EP2857410
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