Extract from the Register of European Patents

EP About this file: EP2727918

EP2727918 - Compounds and Compositions as Protein Kinase Inhibitors [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  18.08.2017
Database last updated on 01.04.2026
Most recent event   Tooltip18.08.2017No opposition filed within time limitpublished on 20.09.2017  [2017/38]
Applicant(s)For all designated states
Array Biopharma Inc.
3200 Walnut Street
Boulder, CO 80301 / US
[2016/35]
Former [2015/14]For all designated states
Novartis AG
Lichtstrasse 35
4056 Basel / CH
Former [2014/19]For all designated states
IRM LLC
131 Front Street PO Box HM 2899
Hamilton HM LX / BM
For all designated states
Novartis AG
Lichtstrasse 35
4056 Basel / CH
Inventor(s)01 / Huang, Shenlin
5768 Cape Jewels Trial
San Diego, CA 92130 / US
02 / Jin, Xianming
3516 Sleeping Meadow Way
San Ramon, CA 94582 / US
03 / Liu, Zuosheng
3911 Tynebourne Circle
San Diego, CA 92130 / US
04 / Poon, Daniel
54 Lake Avenue
Piedmont, CA 94611 / US
05 / Tellew, John
617 Caminito de la Costa
La Jolla, CA 92037 / US
06 / Wan, Yongqin
10675 John Jay Hopkins Drive
San Diego, CA 92121 / US
07 / Wang, Xing
10445 Monterey Ridge Drive
San Diego, CA 92127 / US
08 / Xie, Yongping
12596 Brickella Street
San Diego, CA 92129 / US
 [2014/35]
Former [2014/19]01 / Huang, Shenlin
5768 Cape Jewels Trial
San Diego, CA 92130 / US
02 / Jin, Xianming
3516 Sleeping Meadow Way
San Ramon, CA 94582 / US
03 / Liu, Zuosheng
3911 Tynebourne Circle
San Diego, CA 92130 / US
04 / Poon, Daniel
54 Lake Avenue
Piedmont, CA 94611 / US
05 / Tellew, John
617 Caminito de la Costa
La Jolla, CA 92037 / US
06 / Wan, Yongqin
19 Santa Eugenia
Irvine, CA 92606 / US
07 / Wang, Xing
10445 Monterey Ridge Drive
San Diego, CA 92127 / US
08 / Xie, Yongping
12596 Brickella Street
San Diego, CA 92129 / US
Representative(s)Kiddle, Simon John
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
[2016/41]
Former [2014/19]Kiddle, Simon John
Mewburn Ellis LLP
33 Gutter Lane
London
EC2V 8AS / GB
Application number, filing date14152945.327.08.2010
[2014/19]
Priority number, dateUS20090238073P28.08.2009         Original published format: US 238073 P
US20100313039P11.03.2010         Original published format: US 313039 P
[2014/19]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2727918
Date:07.05.2014
Language:EN
[2014/19]
Type: B1 Patent specification 
No.:EP2727918
Date:12.10.2016
Language:EN
[2016/41]
Search report(s)(Supplementary) European search report - dispatched on:EP03.04.2014
ClassificationIPC:C07D401/14, C07D403/04, A61K31/506, A61P35/00
[2014/19]
CPC:
A61K31/506 (EP,KR,US); C07D403/04 (EP,CN,KR,US); A61K31/4184 (EP,US);
A61K45/06 (EP,US); A61K9/0053 (US); A61P1/08 (EP);
A61P25/24 (EP); A61P35/00 (EP); A61P43/00 (EP);
C07D401/14 (EP,CN,KR,US); C07D405/14 (EP,CN,US) (-)
C-Set:
A61K31/506, A61K2300/00 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2014/19]
Extension statesBA11.02.2014
ME11.02.2014
RS11.02.2014
TitleGerman:Verbindungen und Zusammensetzungen als Proteinkinase-Inhibitoren[2014/19]
English:Compounds and Compositions as Protein Kinase Inhibitors[2014/19]
French:Composés et compositions en tant qu'inhibiteurs de protéine kinase[2014/19]
Examination procedure11.02.2014Examination requested  [2014/19]
27.05.2014Despatch of a communication from the examining division (Time limit: M06)
05.12.2014Reply to a communication from the examining division
08.04.2015Despatch of a communication from the examining division (Time limit: M06)
16.10.2015Reply to a communication from the examining division
17.03.2016Communication of intention to grant the patent
25.07.2016Fee for grant paid
25.07.2016Fee for publishing/printing paid
25.07.2016Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP10748211.9  / EP2470526
Divisional application(s)EP16193397.3   Application deemed to be withdrawn  : 12.11.2016
EP16193400.5   Application withdrawn  : 25.01.2017
Opposition(s)13.07.2017No opposition filed within time limit [2017/38]
Fees paidRenewal fee
11.02.2014Renewal fee patent year 03
11.02.2014Renewal fee patent year 04
13.08.2014Renewal fee patent year 05
27.08.2015Renewal fee patent year 06
29.08.2016Renewal fee patent year 07
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Documents cited:Search[YP] WO2010010154  (NERVIANO MEDICAL SCIENCES SRL et al.)
 [YP] WO2009115572  (NOVARTIS AG et al.)
 [A] WO2008045627  (IRM LLC et al.)
 [A] WO2009016460  (PFIZER et al.)
Examination  MCCUBREY JAMES A ET AL: "Emerging MEK inhibitors.", EXPERT OPINION ON EMERGING DRUGS JUN 2010, vol. 15, no. 2, June 2010 (2010-06-01), pages 203 - 223, ISSN: 1744-7623
   FRMIN CHRISTOPHE ET AL: "From basic research to clinical development of MEK1/2 inhibitors for cancer therapy.", JOURNAL OF HEMATOLOGY & ONCOLOGY 2010, vol. 3, 8, 2010, pages 11PP, ISSN: 1756-8722
   ANONYMOUS: "A Study of ARRY-438162 in Patients With Rheumatoid Arthritis", CLINICALTRIALS.GOV, Retrieved from the Internet [retrieved on 20080331]
   ANONYMOUS: "MEK Inhibitor MSC1936369B Plus FOLFIRI in Second Line K-Ras Mutated Metastatic Colorectal Cancer (mCRC)", CLINICALTRIALS.GOV, Retrieved from the Internet [retrieved on 20100304]
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 US2001006975
 US6911446
 EP0184384
   T.W. GREENE; P. G. M. WUTS: "Protective Groups in Organic Chemistry", 1991, JOHN WILEY AND SONS
   SAULNIER ET AL., BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 4, 1994, pages 1985
   T. W. GREENE: "Protecting Groups in Organic Chemistry", 1999, JOHN WILEY AND SONS, INC.
   JEAN JACQUES; ANDRE COLLET; SAMUEL H. WILEN: "Enantiomers, Racemates and Resolutions", 1981, JOHN WILEY AND SONS, INC.
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