| EP2774925 - Heterocyclic modulators of ATP-binding cassette transporters [Right-click to bookmark this link] | |||
| Former [2014/37] | Pharmaceutical composition containing a heterocyclic modulator of ATP-binding cassette transporters | ||
| [2016/03] | Status | No opposition filed within time limit Status updated on 03.11.2017 Database last updated on 01.04.2026 | |
| Former | The patent has been granted Status updated on 25.11.2016 | ||
| Former | Grant of patent is intended Status updated on 16.11.2016 | Most recent event Tooltip | 03.11.2017 | No opposition filed within time limit | published on 06.12.2017 [2017/49] | Applicant(s) | For all designated states Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston, MA 02210 / US | [2016/52] |
| Former [2014/37] | For all designated states Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston, MA 02210 / US | Inventor(s) | 01 /
Hadida Ruah, Sarah 2356 Torrey Pines 16 La Jolla, CA 92037 / US | 02 /
Hamilton, Matthew 24 Mockingbird Road Hackettstown, NJ 07840 / US | 03 /
Miller, Mark 5075 La Jolla Blvd., 9 San Diego, CA 92109 / US | 04 /
Grootenhuis, Peter D. J. 4801 Riding Ridge Road San Diego, CA 92130 / US | 05 /
Bear, Brian 5108 Spencer Ct. Oceanside, CA 92057 / US | 06 /
McCarthy, Jason 2274 Carol View Drive Apt. 112 Cardiff By The Sea, CA 92007 / US | 07 /
Zhou, Jinglan 4466 Shorepointe Way San Diego, CA 92130 / US | [2014/37] | Representative(s) | Oates, Edward Christopher, et al Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB | [2014/45] |
| Former [2014/44] | Goodfellow, Hugh Robin, et al Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB | ||
| Former [2014/37] | Cohausz & Florack Patent- und Rechtsanwälte Partnerschaftsgesellschaft Bleichstraße 14 40211 Düsseldorf / DE | Application number, filing date | 14163968.2 | 08.11.2006 | [2014/37] | Priority number, date | US20050734506P | 08.11.2005 Original published format: US 734506 P | US20050754086P | 27.12.2005 Original published format: US 754086 P | US20060802458P | 22.05.2006 Original published format: US 802458 P | [2014/37] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP2774925 | Date: | 10.09.2014 | Language: | EN | [2014/37] | Type: | B1 Patent specification | No.: | EP2774925 | Date: | 28.12.2016 | Language: | EN | [2016/52] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 13.08.2014 | Classification | IPC: | C07D405/12, A61K31/443, A61P11/00 | [2014/37] | CPC: |
C07D405/12 (EP,KR,RU,US);
G01N33/6872 (KR);
A61K31/443 (RU,US);
A61K31/444 (US);
A61K31/4525 (KR);
A61K31/4545 (US);
A61K31/47 (US);
A61K31/4709 (US);
A61K31/496 (US);
A61K31/497 (US);
A61K31/501 (US);
A61K31/506 (US);
A61K31/5377 (US);
A61K45/06 (US);
A61P1/00 (EP);
A61P11/00 (EP,RU);
A61P13/00 (EP);
A61P13/02 (EP);
A61P13/12 (EP);
A61P17/00 (EP);
A61P19/00 (EP);
A61P19/04 (EP);
A61P19/08 (EP);
A61P21/00 (EP);
A61P21/02 (EP);
A61P21/04 (EP);
A61P25/00 (EP);
A61P25/14 (EP);
A61P25/16 (EP);
A61P25/28 (EP);
A61P27/02 (EP);
A61P27/04 (EP);
A61P3/00 (EP);
A61P3/06 (EP);
A61P3/08 (EP);
A61P3/10 (EP);
A61P35/00 (EP);
A61P43/00 (EP);
A61P5/00 (EP);
A61P5/14 (EP);
A61P5/16 (EP);
A61P5/18 (EP);
A61P5/50 (EP);
A61P7/00 (EP);
A61P7/02 (EP);
A61P7/12 (EP);
A61P9/00 (EP);
C07D317/12 (EP,US);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2016/52] |
| Former [2014/37] | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR | Title | German: | Heterocyclische Modulatoren von ATP-bindenden Kassettentransportern | [2016/03] | English: | Heterocyclic modulators of ATP-binding cassette transporters | [2016/03] | French: | Modulateurs hétérocycliques de transporteurs à cassette liant l'ATP | [2016/03] |
| Former [2014/37] | Pharmazeutische Zusammensetzung mit einem heterocyclischen Modulator ATP-bindender Kassettentransporter | ||
| Former [2014/37] | Pharmaceutical composition containing a heterocyclic modulator of ATP-binding cassette transporters | ||
| Former [2014/37] | Composition pharmaceutique contenant un modulateur hétérocyclique de transporteurs à cassette liant l'ATP | Examination procedure | 04.03.2015 | Amendment by applicant (claims and/or description) | 04.03.2015 | Examination requested [2015/16] | 27.07.2015 | Despatch of a communication from the examining division (Time limit: M04) | 07.12.2015 | Reply to a communication from the examining division | 21.01.2016 | Communication of intention to grant the patent | 25.05.2016 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 07.07.2016 | Communication of intention to grant the patent | 16.11.2016 | Fee for grant paid | 16.11.2016 | Fee for publishing/printing paid | 16.11.2016 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP06837028.7 / EP1945632 | EP10192912.3 / EP2395002 | Divisional application(s) | EP16205718.6 / EP3208272 | EP20150602.9 | Opposition(s) | 29.09.2017 | No opposition filed within time limit [2017/49] | Fees paid | Renewal fee | 09.04.2014 | Renewal fee patent year 03 | 09.04.2014 | Renewal fee patent year 04 | 09.04.2014 | Renewal fee patent year 05 | 09.04.2014 | Renewal fee patent year 06 | 09.04.2014 | Renewal fee patent year 07 | 09.04.2014 | Renewal fee patent year 08 | 10.11.2014 | Renewal fee patent year 09 | 10.11.2015 | Renewal fee patent year 10 | 10.11.2016 | Renewal fee patent year 11 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | deleted | [2017/22] |
| Former [2017/12] | LV | 28.12.2016 | Documents cited: | Search | [A] WO2005075435 (VERTEX PHARMA et al.) | by applicant | US6099562 | US5886026 | US5304121 | GREGORY, R. J. ET AL., NATURE, vol. 347, 1990, pages 382 - 386 | RICH, D. P. ET AL., NATURE, vol. 347, 1990, pages 358 - 362 | RIORDAN, J. R. ET AL., SCIENCE, vol. 245, 1989, pages 1 066 - 1 073 | CUTTING, G. R. ET AL., NATURE, vol. 346, 1990, pages 366 - 369 | DEAN, M. ET AL., CELL, vol. 61, 1990, pages 863 - 870 | KEREM, B-S. ET AL., SCIENCE, vol. 245, 1989, pages 1073 - 1080 | KEREM, B-S ET AL., PROC. NATL. ACAD. SCI. USA, vol. 87, 1990, pages 8447 - 8451 | QUINTON, P. M., FASEB J., vol. 4, 1990, pages 2709 - 2727 | DALEMANS ET AL., NATURE LOND., vol. 354, 1991, pages 526 - 528 | PASYK; FOSKETT, J. CELL. BIOCHEM., vol. 270, 1995, pages 12347 - 50 | ARIDOR M ET AL., NATURE MED., vol. 5, no. 7, 1999, pages 745 - 751 | SHASTRY, B.S. ET AL., NEUROCHEM. INTERNATIONAL, vol. 43, 2003, pages 1 - 7 | RUTISHAUSER, J. ET AL., SWISS MED WKLY, vol. 132, 2002, pages 211 - 222 | MORELLO, JP ET AL., TIPS, vol. 21, 2000, pages 466 - 469 | BROSS P. ET AL., HUMAN MUT., vol. 14, 1999, pages 186 - 198 | HWANG, T. C. ET AL., J. GEN. PHYSIOL., vol. 111, no. 3, 1998, pages 477 - 90 | "Handbook of Chemistry and Physics" | THOMAS SORRELL: "Organic Chemistry", 1999, UNIVERSITY SCIENCE BOOKS | "March's Advanced Organic Chemistry", 2001, JOHN WILEY & SONS | FREIREICH ET AL., CANCER CHEMOTHER. REP, vol. 50, 1966, pages 219 | "Scientific Tables, Geigy Pharmaceuticals", 1970, ARDSLEY, pages: 537 | S. M. BERGE ET AL.: "pharmaceutically acceptable salts in detail", J. PHARMACEUTICAL SCIENCES, vol. 66, 1977, pages 1 - 19 | REMINGTON: "The Science and Practice of Pharmacy", 2005, LIPPINCOTT WILLIAMS & WILKINS | "Encyclopedia of Pharmaceutical Technology", 1988, MARCEL DEKKER | GONZALEZ, J. E.; R. Y. TSIEN: "Voltage sensing by fluorescence resonance energy transfer in single cells", BIOPHYS J, vol. 69, no. 4, 1995, pages 1272 - 80, XP000961694 | GONZALEZ, J. E.; R. Y. TSIEN: "Improved indicators of cell membrane potential that use fluorescence resonance energy transfer", CHEM BIOL, vol. 4, no. 4, 1997, pages 269 - 77, XP000961796, DOI: doi:10.1016/S1074-5521(97)90070-3 DOI: http://dx.doi.org/10.1016/S1074-5521(97)90070-3 | GONZALEZ, J. E., K. OADES ET AL.: "Cell-based assays and instrumentation for screening ion-channel targets", DRUG DISCOV TODAY, vol. 4, no. 9, 1999, pages 431 - 439, XP001026838, DOI: doi:10.1016/S1359-6446(99)01383-5 DOI: http://dx.doi.org/10.1016/S1359-6446(99)01383-5 | GONZALEZ, J. E.; K. OADES ET AL.: "Cell-based assays and instrumentation for screening ion-channel targets", DRUG DISCOV TODAY, vol. 4, no. 9, 1999, pages 431 - 439, XP001026838, DOI: doi:10.1016/S1359-6446(99)01383-5 DOI: http://dx.doi.org/10.1016/S1359-6446(99)01383-5 |