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Extract from the Register of European Patents

EP About this file: EP2943592

EP2943592 - NONINVASIVE PRENATAL MOLECULAR KARYOTYPING FROM MATERNAL PLASMA [Right-click to bookmark this link]
StatusThe patent has been granted
Status updated on  06.10.2023
Database last updated on 24.04.2024
FormerGrant of patent is intended
Status updated on  18.05.2023
FormerExamination is in progress
Status updated on  14.05.2019
Most recent event   Tooltip06.10.2023(Expected) grantpublished on 08.11.2023  [2023/45]
06.10.2023Change - divisional application(s)published on 08.11.2023  [2023/45]
Applicant(s)For all designated states
The Chinese University Of Hong Kong
Office Of Research And Knowledge Transfer Services
Room 301, Pi Ch'iu Building
Shatin, New Territories / HK
[N/P]
Former [2023/43]For all designated states
The Chinese University Of Hong Kong
Office Of Research And Knowledge Transfer Services
Room 301, Pi Ch'iu Building
Shatin, New Territories
Hong Kong / CN
Former [2015/47]For all designated states
The Chinese University Of Hong Kong
Shatin, N.T.
Hong Kong / CN
Inventor(s)01 / CHIU, Wai Kwun Rossa
House 31
Double Haven
52 Ma Lok Path
Shatin New Territories Hong Kong SAR / CN
02 / LO, Yuk Ming Dennis
4th Floor
7 King Tak Street
Homantin
Kowloon Hong Kong SAR / CN
03 / CHAN, Kwan Chee
Flat A
13/F
Block 34
Broadway Street, Mei Foo Sun Chuen
Kowloon Hong Kong SAR / CN
04 / JIANG, Peiyong
Flat 7, 1/F Block B, Kwong Lam Court
62-66 Siu Lek Yuen Road
Shatin New Territories Hong Kong SAR / CN
05 / YU, Cheuk Yin Jandy
20/F, Block5, Double Cove
8 Wu Kai Sha Road
Ma On Shan
New Territories Hong Kong SAR / CN
 [2015/47]
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[2023/45]
Former [2015/47]Merryweather, Colin Henry
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date14737956.409.01.2014
[2015/47]
WO2014AU00012
Priority number, dateUS201361751213P10.01.2013         Original published format: US 201361751213 P
US20131383777615.03.2013         Original published format: US201313837776
[2015/47]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014107765
Date:17.07.2014
Language:EN
[2014/29]
Type: A1 Application with search report 
No.:EP2943592
Date:18.11.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 17.07.2014 takes the place of the publication of the European patent application.
[2015/47]
Type: B1 Patent specification 
No.:EP2943592
Date:08.11.2023
Language:EN
[2023/45]
Search report(s)International search report - published on:AU17.07.2014
(Supplementary) European search report - dispatched on:EP28.07.2016
ClassificationIPC:G16B20/00, G16B20/10
[2023/21]
CPC:
G16B20/00 (EP,KR,US); G16B20/10 (EP,KR,US); C12Q1/6827 (KR);
G16B30/10 (US)
Former IPC [2016/35]G06F19/18
Former IPC [2015/47]C12Q1/68
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/47]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:NICHTINVASIVE PRÄNATALE MOLEKULARE KARYOTYPISIERUNG AUS MATERNALEM PLASMA[2015/47]
English:NONINVASIVE PRENATAL MOLECULAR KARYOTYPING FROM MATERNAL PLASMA[2015/47]
French:CARYOTYPAGE MOLÉCULAIRE PRÉNATAL NON INVASIF À PARTIR DE PLASMA MATERNEL[2015/47]
Entry into regional phase23.06.2015National basic fee paid 
23.06.2015Search fee paid 
23.06.2015Designation fee(s) paid 
23.06.2015Examination fee paid 
Examination procedure23.06.2015Examination requested  [2015/47]
10.02.2017Amendment by applicant (claims and/or description)
22.05.2019Despatch of a communication from the examining division (Time limit: M04)
11.09.2019Reply to a communication from the examining division
18.03.2021Despatch of a communication from the examining division (Time limit: M04)
21.05.2021Reply to a communication from the examining division
13.02.2023Despatch of a communication from the examining division (Time limit: M02)
13.04.2023Reply to a communication from the examining division
19.05.2023Communication of intention to grant the patent
28.09.2023Fee for grant paid
28.09.2023Fee for publishing/printing paid
28.09.2023Receipt of the translation of the claim(s)
Divisional application(s)EP23200760.9
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  22.05.2019
Fees paidRenewal fee
11.01.2016Renewal fee patent year 03
11.01.2017Renewal fee patent year 04
15.01.2018Renewal fee patent year 05
15.01.2019Renewal fee patent year 06
14.01.2020Renewal fee patent year 07
13.01.2021Renewal fee patent year 08
16.12.2021Renewal fee patent year 09
14.11.2022Renewal fee patent year 10
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[I]WO2012071621  (UNIV HONG KONG CHINESE [CN], et al) [I] 1-15 * abstract * * [0007], [0008], [0009], [0050], [0052], [0085], [0095], [0145], [0161], [0162], [0166] *;
 [A]US2012237928  (RAVA RICHARD P [US], et al) [A] 1-15 * abstract *;
 [A]  - LO Y M DENNIS ET AL, "Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus", SCIENCE TRANSLATIONAL MEDICINE, AAAS - AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, (20101208), vol. 2, no. 61, doi:10.1126/SCITRANSLMED.3001720, ISSN 1946-6242, pages 61ra91 - 1, XP008132703 [A] 1-15 * abstract * * page 4, column 1, paragraph 2 *

DOI:   http://dx.doi.org/10.1126/scitranslmed.3001720
 [A]  - JOEP DE LIGT ET AL, "P1-47: Massively parallel sequencing for noninvasive prenatal diagnosis of partial feta aneuploidies", PRENATAL DIAGNOSIS; ISPD 16TH INTERNATIONAL CONFERENCE ON PRENATAL DIAGNOSIS AND THERAPY, CHICHESTER, SUSSEX, GB; MIAMI, USA, vol. 32, no. Suppl. 1, doi:10.1111/J.1097-0223.2012.03905_X.X, ISSN 0197-3851, (20120601), page 59, (20120601), XP008179757 [A] 1-15 * page 59, column 1, paragraph 2 - column 2, paragraph 1 *

DOI:   http://dx.doi.org/10.1111/j.1097-0223.2012.03905_x.x
International search[A]US2012237928  (RAVA RICHARD P [US], et al);
 [A]  - DE LIGT, J. ET AL., "Massively parallel sequencing for noninvasive prenatal diagnosis of partial feta aneuploidies", PRENATAL DIAGNOSIS., (2012), vol. 32, no. SUPP., page 59, XP008179757

DOI:   http://dx.doi.org/10.1111/j.1097-0223.2012.03905_x.x
 [XP]  - YU, S.C.Y. ET AL., "Noninvasive prenatal molecular karyotyping from maternal plasma", PLOS ONE., (201304), vol. 8, no. ISSUE, page E60968, XP055160833

DOI:   http://dx.doi.org/10.1371/journal.pone.0060968
 [XP]  - SRINIVASAN, A. ET AL., "Noninvasive detection of fetal subchromosome abnormalities via deep sequencing of maternal plasma", THE AMERICAN JOURNAL OF HUMAN GENETICS., (20130207), vol. 92, pages 167 - 176, XP055125834

DOI:   http://dx.doi.org/10.1016/j.ajhg.2012.12.006
 [XP]  - CHEN, S. ET AL., "A method for noninvasive detection of fetal large deletions/duplications by low coverage massively parallel sequencing''.", PRENATAL DIAGNOSIS., (2013), vol. 33, pages 584 - 590, XP055136781

DOI:   http://dx.doi.org/10.1002/pd.4110
Examination   - Anupama Srinivasan ET AL, "Noninvasive Detection of Fetal Subchromosome Abnormalities via Deep Sequencing of Maternal Plasma", The American Journal of Human Genetics, (20130201), vol. 92, no. 2, doi:10.1016/j.ajhg.2012.12.006, ISSN 0002-9297, pages 167 - 176, XP055125834

DOI:   http://dx.doi.org/10.1016/j.ajhg.2012.12.006
    - Stephanie C. Y. Yu ET AL, "Noninvasive Prenatal Molecular Karyotyping from Maternal Plasma", PLoS ONE, (20130417), vol. 8, no. 4, doi:10.1371/journal.pone.0060968, page e60968, XP055160833

DOI:   http://dx.doi.org/10.1371/journal.pone.0060968
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.