Extract from the Register of European Patents

EP About this file: EP2959005

EP2959005 - MEDICAL USE RELATING TO TELOMERE EXTENSION [Right-click to bookmark this link]
Former [2016/01]COMPOUNDS, COMPOSITIONS, METHODS, AND KITS RELATING TO TELOMERE EXTENSION
[2021/21]
StatusNo opposition filed within time limit
Status updated on  12.08.2022
Database last updated on 09.04.2026
FormerThe patent has been granted
Status updated on  03.09.2021
FormerGrant of patent is intended
Status updated on  29.04.2021
FormerExamination is in progress
Status updated on  08.06.2018
Most recent event   Tooltip24.01.2025Change - lapse in a contracting state
State(s) deleted from list of lapses: FI
published on 26.02.2025  [2025/09]
Applicant(s)For all designated states
The Board of Trustees of the Leland Stanford Junior University
Office of the General Counsel
Building 170, Third Floor, Main Quad
P.O. Box 20386
Stanford, CA 94305-2038 / US
[2019/38]
Former [2016/01]For all designated states
The Board of Trustees of the Leland Stanford Junior University
Office of Technology Licensing
1705 El Camino Real
Palo Alto, CA 94306 / US
Inventor(s)01 / RAMUNAS, John
425 Olive Street
Menlo Park, California 94025 / US
02 / YAKUBOV, Eduard
2600 Gramercy Street
332
Houston, Texas 77030 / US
03 / BLAU, Helen M.
580 Cotton Street
Menlo Park, California 94025 / US
04 / COOKE, John
Apt. 845
Arcadian Kirby
7550 Kirby Drive
Houston, Texas 77030 / US
 [2016/01]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[2016/01]
Application number, filing date14754545.322.02.2014
[2016/01]
WO2014US17867
Priority number, dateUS201361768047P22.02.2013         Original published format: US 201361768047 P
[2016/01]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014130909
Date:28.08.2014
Language:EN
[2014/35]
Type: A1 Application with search report 
No.:EP2959005
Date:30.12.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 28.08.2014 takes the place of the publication of the European patent application.
[2015/53]
Type: B1 Patent specification 
No.:EP2959005
Date:06.10.2021
Language:EN
[2021/40]
Search report(s)International search report - published on:US28.08.2014
(Supplementary) European search report - dispatched on:EP22.11.2016
ClassificationIPC:A61K38/45, A61K31/7088
[2021/21]
CPC:
A61K31/7088 (EP,IL,US); A61K31/7115 (IL,RU); A61K38/45 (EP,IL,RU,US);
A61P1/04 (EP,IL); A61P1/14 (EP,IL); A61P1/16 (EP,IL);
A61P11/00 (EP,IL); A61P13/00 (EP,IL); A61P13/02 (EP,IL);
A61P19/00 (EP,IL); A61P19/02 (EP,IL); A61P19/08 (EP,IL);
A61P19/10 (EP,IL); A61P25/00 (EP,IL); A61P25/02 (EP,IL);
A61P25/16 (EP,IL); A61P25/18 (EP,IL); A61P25/22 (EP,IL);
A61P25/24 (EP,IL); A61P25/28 (EP,IL); A61P27/00 (EP,IL);
A61P27/02 (EP,IL); A61P27/06 (EP,IL); A61P27/12 (EP,IL);
A61P27/16 (EP,IL); A61P29/00 (EP,IL); A61P3/00 (EP,IL);
A61P3/02 (EP,IL); A61P3/04 (EP,IL); A61P3/10 (EP,IL);
A61P31/00 (EP,IL); A61P31/16 (EP,IL); A61P35/00 (EP,IL);
A61P37/02 (EP,IL); A61P43/00 (EP,IL); A61P7/00 (EP,IL);
A61P9/00 (EP,IL); A61P9/10 (EP,IL); C12N15/52 (IL,RU,US);
C12N9/1276 (EP,IL,RU,US); C12Y207/07049 (EP,IL,RU,US) (-)
Former IPC [2016/51]C12P19/34, A61K38/45
Former IPC [2016/01]C12P19/34
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/01]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:MEDIZINISCHE VERWENDUNG BEZÜGLICH TELOMERVERLÄNGERUNG[2021/21]
English:MEDICAL USE RELATING TO TELOMERE EXTENSION[2021/21]
French:USAGE MÉDICAL LIÉ À L'EXTENSION DE TÉLOMÈRES[2021/21]
Former [2016/01]VERBINDUNGEN, ZUSAMMENSETZUNGEN, VERFAHREN UND KITS BEZÜGLICH TELOMERVERLÄNGERUNG
Former [2016/01]COMPOUNDS, COMPOSITIONS, METHODS, AND KITS RELATING TO TELOMERE EXTENSION
Former [2016/01]COMPOSÉS, COMPOSITIONS, PROCÉDÉS, ET KITS LIÉS À L'EXTENSION DE TÉLOMÈRES
Entry into regional phase22.09.2015National basic fee paid 
22.09.2015Search fee paid 
22.09.2015Designation fee(s) paid 
22.09.2015Examination fee paid 
Examination procedure22.09.2015Examination requested  [2015/53]
19.06.2017Amendment by applicant (claims and/or description)
12.06.2018Despatch of a communication from the examining division (Time limit: M04)
22.10.2018Reply to a communication from the examining division
26.09.2019Despatch of a communication from the examining division (Time limit: M07)
08.05.2020Reply to a communication from the examining division
18.01.2021Date of oral proceedings
02.02.2021Despatch of a communication from the examining division (Time limit: M02)
02.02.2021Minutes of oral proceedings despatched
12.04.2021Reply to a communication from the examining division
30.04.2021Communication of intention to grant the patent
27.08.2021Fee for grant paid
27.08.2021Fee for publishing/printing paid
27.08.2021Receipt of the translation of the claim(s)
Divisional application(s)EP21200777.7  / EP3988112
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  12.06.2018
Opposition(s)07.07.2022No opposition filed within time limit [2022/37]
Fees paidRenewal fee
22.02.2016Renewal fee patent year 03
27.02.2017Renewal fee patent year 04
26.02.2018Renewal fee patent year 05
26.02.2019Renewal fee patent year 06
26.02.2020Renewal fee patent year 07
22.02.2021Renewal fee patent year 08
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Lapses during opposition  TooltipEE06.10.2021
MK06.10.2021
SK06.10.2021
SM06.10.2021
IS06.02.2022
[2025/09]
Former [2024/22]EE06.10.2021
FI06.10.2021
MK06.10.2021
SK06.10.2021
SM06.10.2021
IS06.02.2022
Former [2022/36]EE06.10.2021
FI06.10.2021
SK06.10.2021
SM06.10.2021
IS06.02.2022
Former [2022/34]EE06.10.2021
FI06.10.2021
SM06.10.2021
IS06.02.2022
Former [2022/33]FI06.10.2021
SM06.10.2021
IS06.02.2022
Former [2022/25]FI06.10.2021
IS06.02.2022
Former [2022/22]FI06.10.2021
Documents cited:Search[X] WO2011130624  (IMMUNE DISEASE INST INC et al.) [X] 1-6,9,12,13 * paragraph [0341]; claims 56-66 *
International search[Y] US8323975  (KOOL ERIC T et al.) [Y]
 [Y] US2011143397  (KARIKO KATALIN et al.) [Y]
 [Y]   GREIDER, CW ET AL.: "Telomeres, Telomerase and Senescence.", BIOESSAYS., vol. 12, no. 8, August 1990 (1990-08-01), pages 363 - 369, XP055278069 [Y]

DOI:   http://dx.doi.org/10.1002/bies.950120803
 [Y]   KARIKO, K ET AL.: "Incorporation Of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity And Biological Stability.", MOLECULAR THERAPY., vol. 16, 2008, pages 1833 - 1840, XP002598556 [Y]

DOI:   http://dx.doi.org/10.1038/mt.2008.200
Examination  BRUNO BERNARDES DE JESUS ET AL: "Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer : TERT alone extends lifespan of adult/old mice", EMBO MOLECULAR MEDICINE, vol. 4, no. 8, 15 May 2012 (2012-05-15), Weinheim, pages 691 - 704, XP055384661, ISSN: 1757-4676, DOI: 10.1002/emmm.201200245

DOI:   http://dx.doi.org/10.1002/emmm.201200245
   VIRGINIA BOCCARDI ET AL: "Telomerase gene therapy: a novel approach to combat aging : Telomerase gene therapy", EMBO MOLECULAR MEDICINE, vol. 4, no. 8, 1 August 2012 (2012-08-01), Weinheim, pages 685 - 687, XP055481726, ISSN: 1757-4676, DOI: 10.1002/emmm.201200246

DOI:   http://dx.doi.org/10.1002/emmm.201200246
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