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Extract from the Register of European Patents

EP About this file: EP3103447

EP3103447 - DETECTION AND USE OF LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8 [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  11.06.2021
Database last updated on 17.05.2024
FormerThe patent has been granted
Status updated on  03.07.2020
FormerGrant of patent is intended
Status updated on  27.02.2020
FormerExamination is in progress
Status updated on  17.02.2020
FormerGrant of patent is intended
Status updated on  16.10.2019
FormerExamination is in progress
Status updated on  15.06.2018
FormerRequest for examination was made
Status updated on  23.06.2017
FormerThe application has been published
Status updated on  11.11.2016
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
BASF SE
Carl-Bosch-Strasse 38
67056 Ludwigshafen am Rhein / DE
[2020/32]
Former [2016/50]For all designated states
BASF SE
Carl-Bosch-Strasse 38
67056 Ludwigshafen am Rhein / DE
Inventor(s)01 / SUBKOWSKI, Thomas
Wichernstr. 13
68526 Ladenburg / DE
02 / BOLLSCHWEILER, Claus
Karl-Christ-Str. 13
69118 Heidelberg / DE
03 / WITTENBERG, Jens
Mainstr. 6
67117 Limburgerhof / DE
04 / KROHN, Michael
Alexanderstr. 8
64653 Lorsch / DE
05 / ZINKE, Holger
Darmstädter Str. 36
64673 Zwingenberg / DE
 [2016/50]
Representative(s)(deleted)
[2020/32]
Former [2016/50]Reitstötter Kinzebach
Patentanwälte
Sternwartstrasse 4
81679 München / DE
Application number, filing date16175302.526.08.2009
[2016/50]
Priority number, dateEP2008016299726.08.2008         Original published format: EP 08162997
[2016/50]
Filing languageDE
Procedural languageDE
PublicationType: A1 Application with search report 
No.:EP3103447
Date:14.12.2016
Language:DE
[2016/50]
Type: B1 Patent specification 
No.:EP3103447
Date:05.08.2020
Language:DE
[2020/32]
Search report(s)(Supplementary) European search report - dispatched on:EP26.10.2016
ClassificationIPC:A61K31/135, A61K31/155, A61K31/357, A61K31/381, A61K31/4164, A61K31/443, A61K31/445, A61K31/4743, A61K31/496, A61K31/506, A61P13/02, A61P35/00, A61P29/00, A61G9/00, A61K6/00, A61K8/00, A61Q11/02, A61Q17/02, A23G9/00
[2016/50]
CPC:
C07D495/22 (EP,US); A61K31/451 (CN); A23C13/125 (CN);
A23G9/32 (CN); A23L2/52 (CN); A23L27/88 (EP,US);
A23L29/035 (CN); A23L29/045 (CN); A23L29/055 (CN);
A61K31/00 (EP,US); A61K31/137 (CN); A61K31/165 (CN);
A61K31/17 (CN); A61K31/381 (CN); A61K31/403 (CN);
A61K31/4174 (CN); A61K31/4439 (CN); A61K31/445 (CN);
A61K31/495 (CN); A61K31/498 (CN); A61K8/42 (EP,CN,US);
A61K8/49 (EP,CN,US); A61K8/4926 (EP,CN,US); A61K8/494 (CN);
A61K8/4946 (EP,CN,US); A61K8/4953 (EP,US); A61K8/4973 (EP,CN,US);
A61K8/4986 (CN); A61K8/69 (EP,CN,US); A61P13/02 (EP);
A61P13/08 (EP); A61P13/10 (EP); A61P25/00 (EP);
A61P25/04 (EP); A61P29/00 (EP); A61P33/00 (EP);
A61P35/00 (EP); A61P43/00 (EP); A61Q11/00 (EP,CN,US);
A61Q17/02 (EP,US); A61Q17/04 (EP,US); A61Q19/00 (CN);
A61Q19/004 (EP,US); A61Q5/02 (EP,US); A61Q5/12 (CN);
C07C275/28 (US); C07D211/14 (EP,US); C07D233/84 (EP,US);
C07D241/44 (EP,US); C07D317/64 (EP,US); C07D401/04 (EP,US);
C07D401/12 (EP,US); C07D409/12 (EP,US); C07D495/20 (EP,US);
C08K5/20 (CN); C08K5/3432 (CN); C08K5/3462 (CN);
C08K5/45 (CN); D06M13/355 (CN); D06M13/402 (CN);
D06M13/408 (CN); D06M13/418 (CN); D06M13/432 (CN);
D21H17/07 (CN); D21H17/09 (CN); A61K2800/244 (EP,CN,US);
A61K2800/78 (US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2017/30]
Former [2016/50]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  SM,  TR 
TitleGerman:NACHWEIS UND VERWENDUNG NIEDERMOLEKULARER MODULATOREN DES KÄLTE-MENTHOL-REZEPTORS TRPM8[2016/50]
English:DETECTION AND USE OF LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8[2016/50]
French:VERIFICATION ET UTILISATION DE MODULATEURS SOUS-MOLECULAIRES DU RECEPTEUR DE FROID ET DE MENTHOL TRPM8[2016/50]
Examination procedure20.06.2016Date on which the examining division has become responsible
14.06.2017Amendment by applicant (claims and/or description)
14.06.2017Examination requested  [2017/30]
13.06.2018Despatch of a communication from the examining division (Time limit: M06)
21.12.2018Reply to a communication from the examining division
17.10.2019Communication of intention to grant the patent
14.02.2020Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
11.03.2020Communication of intention to grant the patent
19.06.2020Fee for grant paid
19.06.2020Fee for publishing/printing paid
19.06.2020Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP09782234.0  / EP2349239
Opposition(s)07.05.2021No opposition filed within time limit [2021/28]
Fees paidRenewal fee
20.10.2016Renewal fee patent year 03
20.10.2016Renewal fee patent year 04
20.10.2016Renewal fee patent year 05
20.10.2016Renewal fee patent year 06
20.10.2016Renewal fee patent year 07
20.10.2016Renewal fee patent year 08
31.08.2017Renewal fee patent year 09
31.08.2018Renewal fee patent year 10
02.09.2019Renewal fee patent year 11
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU26.08.2009
CY05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
FI05.08.2020
HR05.08.2020
IT05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
MK05.08.2020
MT05.08.2020
PL05.08.2020
RO05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
TR05.08.2020
AT26.08.2020
IE26.08.2020
LU26.08.2020
BE31.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
[2022/32]
Former [2022/27]HU26.08.2009
CY05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
FI05.08.2020
HR05.08.2020
IT05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
MT05.08.2020
PL05.08.2020
RO05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
TR05.08.2020
AT26.08.2020
IE26.08.2020
LU26.08.2020
BE31.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/47]CZ05.08.2020
DK05.08.2020
EE05.08.2020
FI05.08.2020
HR05.08.2020
IT05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
PL05.08.2020
RO05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
AT26.08.2020
IE26.08.2020
LU26.08.2020
BE31.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/37]CZ05.08.2020
DK05.08.2020
EE05.08.2020
FI05.08.2020
HR05.08.2020
IT05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
PL05.08.2020
RO05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
IE26.08.2020
LU26.08.2020
BE31.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/36]CZ05.08.2020
DK05.08.2020
EE05.08.2020
FI05.08.2020
HR05.08.2020
IT05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
PL05.08.2020
RO05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
LU26.08.2020
BE31.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/34]CZ05.08.2020
DK05.08.2020
EE05.08.2020
FI05.08.2020
HR05.08.2020
IT05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
PL05.08.2020
RO05.08.2020
SE05.08.2020
SK05.08.2020
SM05.08.2020
LU26.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/28]CZ05.08.2020
DK05.08.2020
EE05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
PL05.08.2020
RO05.08.2020
SE05.08.2020
SK05.08.2020
SM05.08.2020
LU26.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/27]CZ05.08.2020
DK05.08.2020
EE05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
PL05.08.2020
RO05.08.2020
SE05.08.2020
SM05.08.2020
LU26.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/22]CZ05.08.2020
DK05.08.2020
EE05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
PL05.08.2020
RO05.08.2020
SE05.08.2020
SM05.08.2020
LU26.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/20]DK05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
PL05.08.2020
SE05.08.2020
LU26.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/10]FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
PL05.08.2020
SE05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/09]FI05.08.2020
LT05.08.2020
SE05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
PT07.12.2020
Former [2021/08]FI05.08.2020
LT05.08.2020
SE05.08.2020
BG05.11.2020
NO05.11.2020
PT07.12.2020
Former [2021/07]FI05.08.2020
LT05.08.2020
NO05.11.2020
Documents cited:Search[X]SU776048  (INST BISORGANICHESKOJ KHIM AN [SU], et al) [X] 4,5,8-10,12 * abstract *;
 [AD]WO2004026840  (UNILEVER PLC [GB], et al) [AD] 1-12 * page 7, line 24 - line 25 * * compound - *;
 [A]US2005084447  (WEI EDWARD T [US]) [A] 1-12 * page 2, column 2 *;
 [A]WO2007017093  (BAYER HEALTHCARE AG [DE], et al) [A] 1-12 * example - * * page 1 *;
 [A]WO2008015403  (UNIV EDINBURGH [GB], et al) [A] 1-12 * page 6, paragraph 1 *;
 [X]  - GULYAKEVICH O V ET AL, "Synthesis and properties of dithioacetals of conformationally restricted 8-azasteroid .alpha.-acyl-.beta.-aminovinyl ketones", HCAPLUS,, (19950101), Database accession no. 1995-581648 581648, URL: HCAPLUS, XP002616826 [X] 9,12 * abstract *
by applicantGB1315761
 WO0215692
 US2003207904
 WO2004000023
 US2004028714
 WO2004026840
 US6893626
 WO2007019719
    - PEIER AM ET AL., "A TRP channel that senses cold stimuli and menthol", CELL, (20020308), vol. 108, no. 5, doi:doi:10.1016/S0092-8674(02)00652-9, pages 705 - 15, XP002246274

DOI:   http://dx.doi.org/10.1016/S0092-8674(02)00652-9
    - MCKEMY DD ET AL., "Identification of a cold receptor reveals a general role for TRP channels in thermosensation", NATURE, (20020307), vol. 416, no. 6876, doi:doi:10.1038/nature719, pages 52 - 8, XP002250383

DOI:   http://dx.doi.org/10.1038/nature719
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    - MCKEMY D.D., MOLECULAR PAIN, (2005), vol. 1, page 16
    - MCKEMY D.D., NATURE, (2002), vol. 416, pages 52 - 58
    - PEIER A.M., CELL, (2002), vol. 108, pages 705 - 715
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    - WATSON H.R., J. SOC. COSMET. CHEM., (1978), vol. 29, pages 185 - 200
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.