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Extract from the Register of European Patents

EP About this file: EP3350157

EP3350157 - COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  11.11.2022
Database last updated on 24.04.2024
FormerThe patent has been granted
Status updated on  03.12.2021
FormerGrant of patent is intended
Status updated on  03.08.2021
FormerExamination is in progress
Status updated on  31.08.2019
FormerRequest for examination was made
Status updated on  22.06.2018
FormerThe international publication has been made
Status updated on  25.03.2017
Most recent event   Tooltip11.11.2022No opposition filed within time limitpublished on 14.12.2022  [2022/50]
Applicant(s)For all designated states
ModernaTX, Inc.
200 Technology Square
Cambridge, MA 02139 / US
[2022/23]
Former [2018/30]For all designated states
Modernatx, Inc.
200 Technology Square
Cambridge, MA 02139 / US
Inventor(s)01 / BENENATO, Kerry, E.
200 Technology Square
Cambridge, MA 02139 / US
02 / KUMARASINGHE, Ellalahewage, Sathyajith
200 Technology Square
Cambridge, MA 02139 / US
03 / CORNEBISE, Mark
200 Technology Square
Cambridge, MA 02139 / US
 [2018/30]
Representative(s)Cooley (UK) LLP
22 Bishopsgate
London EC2N 4BQ / GB
[2022/01]
Former [2018/30]Cooley (UK) LLP
Dashwood
69 Old Broad Street
London EC2M 1QS / GB
Application number, filing date16781895.416.09.2016
[2018/30]
WO2016US52352
Priority number, dateUS201562220085P17.09.2015         Original published format: US 201562220085 P
US201562220091P17.09.2015         Original published format: US 201562220091 P
US201562252316P06.11.2015         Original published format: US 201562252316 P
US201562253433P10.11.2015         Original published format: US 201562253433 P
US201562266460P11.12.2015         Original published format: US 201562266460 P
US201662333557P09.05.2016         Original published format: US 201662333557 P
US201662382740P01.09.2016         Original published format: US 201662382740 P
US201662393940P13.09.2016         Original published format: US 201662393940 P
[2018/30]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2017049245
Date:23.03.2017
Language:EN
[2017/12]
Type: A2 Application without search report 
No.:EP3350157
Date:25.07.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 23.03.2017 takes the place of the publication of the European patent application.
[2018/30]
Type: B1 Patent specification 
No.:EP3350157
Date:05.01.2022
Language:EN
[2022/01]
Search report(s)International search report - published on:EP18.05.2017
ClassificationIPC:C07C229/12, C07D233/72, A61K9/127, C07C271/20, C07C279/12, C07C279/28, C07C279/32, C07C311/07, C07C311/49, C07C321/14, C07D249/04, C07D263/20, C07C237/04, C07C237/06, C07D265/33, C07D271/06, C07D271/10, C07D207/27, C07D277/38
[2018/30]
CPC:
C07C229/12 (EP,US); A61K31/7105 (EP,US); A61K38/1725 (EP,US);
A61K38/1816 (EP,US); A61K47/543 (EP,US); A61K47/6911 (EP,US);
A61K48/0033 (US); A61K48/005 (US); A61K9/0019 (EP,US);
A61K9/0043 (EP,US); A61K9/0073 (EP,US); A61K9/127 (US);
A61K9/1272 (EP,US); A61K9/1617 (US); A61K9/1641 (US);
A61K9/5123 (US); A61K9/5146 (US); A61P25/00 (EP);
A61P3/00 (EP); A61P3/10 (EP); A61P31/00 (EP);
A61P35/00 (EP); A61P37/04 (EP); A61P37/06 (EP);
A61P43/00 (EP); A61P9/00 (EP); C07C227/16 (US);
C07C227/18 (US); C07C229/16 (EP,US); C07C233/36 (EP,US);
C07C233/72 (US); C07C235/10 (EP,US); C07C255/24 (EP,US);
C07C263/20 (US); C07C271/20 (EP,US); C07C275/14 (EP,US);
C07C279/12 (EP,US); C07C279/24 (EP,US); C07C279/28 (EP,US);
C07C279/32 (EP,US); C07C311/05 (EP,US); C07C335/08 (EP,US);
C07D207/27 (EP,US); C07D233/72 (EP,US); C07D249/04 (EP,US);
C07D263/20 (EP,US); C07D265/33 (EP,US); C07D271/06 (EP,US);
C07D271/10 (EP,US); C07D277/38 (EP,US); C07F9/091 (EP,US);
C07K14/505 (US); A61K48/00 (US); A61K9/1271 (EP,US);
C07C2601/02 (EP,US); C07C2601/04 (EP,US); C07C2601/14 (EP,US);
C07C2601/18 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/30]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:VERBINDUNGEN UND ZUSAMMENSETZUNGEN ZUR INTRAZELLULÄREN VERABREICHUNG VON THERAPEUTISCHEN WIRKSTOFFEN[2018/30]
English:COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS[2018/30]
French:COMPOSÉS ET COMPOSITIONS POUR L'ADMINISTRATION INTRACELLULAIRE D'AGENTS THÉRAPEUTIQUES[2018/30]
Entry into regional phase17.04.2018National basic fee paid 
17.04.2018Designation fee(s) paid 
17.04.2018Examination fee paid 
Examination procedure17.04.2018Examination requested  [2018/30]
17.04.2018Date on which the examining division has become responsible
03.12.2018Amendment by applicant (claims and/or description)
04.09.2019Despatch of a communication from the examining division (Time limit: M06)
04.03.2020Reply to a communication from the examining division
03.07.2020Despatch of a communication from the examining division (Time limit: M04)
09.11.2020Reply to a communication from the examining division
04.08.2021Communication of intention to grant the patent
26.11.2021Fee for grant paid
26.11.2021Fee for publishing/printing paid
26.11.2021Receipt of the translation of the claim(s)
Divisional application(s)EP20180006.7  / EP3736261
EP23202539.5
Opposition(s)06.10.2022No opposition filed within time limit [2022/50]
Fees paidRenewal fee
27.09.2018Renewal fee patent year 03
13.09.2019Renewal fee patent year 04
14.09.2020Renewal fee patent year 05
15.09.2021Renewal fee patent year 06
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Cited inInternational search[X]US5807861  (KLEIN J PETER [US], et al) [X] 1-4,10,21,22,42,43,45,76,77,108-111 * column 21; compound 3563 * * column 23; compounds 3584, 3593 * * column 25; compound 5574 ** column 27; compound 6533 *;
 [I]WO2009086558  (TEKMIRA PHARMACEUTICALS CORP [CA], et al) [I] 1-4,10-75,78-83,85,86,101,104-188 * Claim 3: in particular fourth and fifth aminolipid structure on page 157 * * claims 4, 10, 11 *;
 [Y]WO2009129395  (ABBOTT LAB [US], et al) [Y] 1-5,10-75,78-86,101,104-188 * claims 1-3 *;
 [Y]WO2009129385  (ABBOTT LAB [US], et al) [Y] 1-5,10-75,78-86,101,104-188 * claims 1-3 *;
 [Y]WO2010030739  (ABBOTT LAB [US], et al) [Y] 1-5,10-75,78-86,101,104-188 * claims 1-3 *;
 [I]WO2013016058  (MERCK SHARP & DOHME [US], et al) [I] 1-5,10-75,78-86,101,104-188 * page 15 - page 20; compounds 6-30 * * page 1, line 6 - line 37 *;
 [XP]WO2015199952  (ACUITAS THERAPEUTICS INC [CA]) [XP] 1-5,10,11,14,15,30,32,34,40,42-45,53,54,69,73,84,105,108,110,111,127,130,131 * precursor C-3 in examples 31 to 33 and 36 according to general reaction scheme 3 *;
 [E]WO2016176330  (UNIV PENNSYLVANIA [US], et al) [E] 1-5,10,11,14,15,30,32,34,40,42-45,53,54,69,73,84,105,108,110,111,127,130,131 * page 92 - page 96; table 3 *
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.