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Extract from the Register of European Patents

EP About this file: EP3350333

EP3350333 - POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION [Right-click to bookmark this link]
StatusPatent maintained as amended
Status updated on  04.07.2025
Database last updated on 31.03.2026
FormerThe patent has been granted
Status updated on  24.09.2021
FormerGrant of patent is intended
Status updated on  05.05.2021
FormerExamination is in progress
Status updated on  24.03.2020
FormerRequest for examination was made
Status updated on  22.06.2018
FormerThe international publication has been made
Status updated on  25.03.2017
Most recent event   Tooltip23.01.2026Change - lapse in a contracting state
State(s) deleted from list of lapses: GR		published on 25.02.2026  [2026/09]
Applicant(s)For all designated states
ModernaTX, Inc.
325 Binney Street
Cambridge, MA 02142 / US
[2024/29]
Former [2018/30]For all designated states
ModernaTX, Inc.
200 Technology Square
Cambridge, MA 02139 / US
Inventor(s)01 / BUTORA, Gabor
c/o Moderna Therapeutics Inc.
200 Technology Square
Cambridge, MA 02139 / US
02 / FRALEY, Andrew, W.
81 Wright Street
Arlington, MA 02474 / US
03 / MIRACCO, Edward, John
110 2nd Street Unit 101
Cambridge, MA 02141 / US
04 / NELSON, Jennifer
465 Washington Street 2
Brookline, MA 02446 / US
05 / RHODEN-SMITH, Amy
4 Churchill Lane
Lexington, MA 02421 / US
06 / STANTON, Matthew
307 Galloping Court
Marlton, NJ 08053 / US
 [2018/30]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
[2018/30]
Application number, filing date16847531.719.09.2016
[2018/30]
WO2016US52451
Priority number, dateUS201562220050P17.09.2015         Original published format: US 201562220050 P
US201662279466P15.01.2016         Original published format: US 201662279466 P
[2018/30]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2017049275
Date:23.03.2017
Language:EN
[2017/12]
Type: A2 Application without search report 
No.:EP3350333
Date:25.07.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 23.03.2017 takes the place of the publication of the European patent application.
[2018/30]
Type: B1 Patent specification 
No.:EP3350333
Date:27.10.2021
Language:EN
[2021/43]
Type: B2 New European patent specification 
No.:EP3350333
Date:06.08.2025
Language:EN
[2025/32]
Search report(s)International search report - published on:US11.05.2017
(Supplementary) European search report - dispatched on:EP07.08.2019
ClassificationIPC:C12N15/67, C07H21/02, A61K31/7115
[2019/23]
CPC:
C07F9/65586 (EP,US); A61K48/0066 (US); C07F9/65616 (EP,US);
C07H21/02 (EP,US); C12N15/67 (US)
Former IPC [2018/30]C12N15/85, C07H21/02, A61K9/51, A61K31/7115
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/30]
TitleGerman:POLYNUKLEOTIDE MIT STABILISIERENDEM SCHWANZBEREICH[2018/30]
English:POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION[2018/30]
French:POLYNUCLÉOTIDES CONTENANT UNE RÉGION DE QUEUE DE STABILISATION[2018/30]
Entry into regional phase13.04.2018National basic fee paid 
13.04.2018Search fee paid 
13.04.2018Designation fee(s) paid 
13.04.2018Examination fee paid 
Examination procedure13.04.2018Examination requested  [2018/30]
13.04.2018Date on which the examining division has become responsible
02.03.2020Amendment by applicant (claims and/or description)
26.03.2020Despatch of a communication from the examining division (Time limit: M04)
05.08.2020Reply to a communication from the examining division
09.09.2020Despatch of a communication from the examining division (Time limit: M04)
18.01.2021Reply to a communication from the examining division
06.05.2021Communication of intention to grant the patent
14.09.2021Fee for grant paid
14.09.2021Fee for publishing/printing paid
14.09.2021Receipt of the translation of the claim(s)
Divisional application(s)EP21204710.4  / EP4101930
Opposition(s)Opponent(s)01  26.07.2022  29.07.2022  ADMISSIBLE
STRAWMAN LIMITED
Orchard Lea
Horns Lane
Combe
Witney, Oxfordshire OX29 8NH / GB
Opponent's representative
Brand Murray Fuller LLP
50 Eastcastle Street
London W1W 8EA / GB
 [2022/36]
08.08.2022Invitation to proprietor to file observations on the notice of opposition
19.12.2022Reply of patent proprietor to notice(s) of opposition
10.10.2024Legal effect of interlocutory decision in opposition
10.10.2024Date of oral proceedings
11.12.2024Despatch of interlocutory decision in opposition
11.12.2024Despatch of minutes of oral proceedings
27.03.2025Despatch of communication that the patent will be maintained as amended
Fees paidRenewal fee
27.11.2018Renewal fee patent year 03
13.09.2019Renewal fee patent year 04
14.09.2020Renewal fee patent year 05
15.09.2021Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
30.09.201803   M06   Fee paid on   27.11.2018
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU19.09.2016
AL27.10.2021
CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
MC27.10.2021
MK27.10.2021
MT27.10.2021
NL27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
AT19.09.2024
CY19.09.2024
FI19.09.2024
LU19.09.2024
SE20.09.2024
CH30.09.2024
DK30.09.2024
NO30.09.2024
[2026/09]
Former [2026/08]HU19.09.2016
AL27.10.2021
CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
MC27.10.2021
MK27.10.2021
MT27.10.2021
NL27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
AT19.09.2024
CY19.09.2024
FI19.09.2024
LU19.09.2024
SE20.09.2024
CH30.09.2024
DK30.09.2024
NO30.09.2024
GR07.04.2025
Former [2026/04]HU19.09.2016
AL27.10.2021
CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
MC27.10.2021
MK27.10.2021
MT27.10.2021
NL27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
AT19.09.2024
CY19.09.2024
FI19.09.2024
LU19.09.2024
SE20.09.2024
CH30.09.2024
DK30.09.2024
NO30.09.2024
PT19.03.2025
GR07.04.2025
Former [2025/47]HU19.09.2016
AL27.10.2021
CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
MC27.10.2021
MK27.10.2021
MT27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
AT19.09.2024
CY19.09.2024
FI19.09.2024
LU19.09.2024
SE20.09.2024
CH30.09.2024
DK30.09.2024
NO30.09.2024
PT19.03.2025
GR07.04.2025
Former [2025/35]HU19.09.2016
AL27.10.2021
CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
MC27.10.2021
MK27.10.2021
MT27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
AT19.09.2024
CY19.09.2024
FI19.09.2024
LU19.09.2024
CH30.09.2024
NO30.09.2024
PT19.03.2025
GR07.04.2025
Former [2025/34]HU19.09.2016
AL27.10.2021
CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
MC27.10.2021
MK27.10.2021
MT27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
CY19.09.2024
FI19.09.2024
LU19.09.2024
NO30.09.2024
PT19.03.2025
Former [2025/26]HU19.09.2016
AL27.10.2021
CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
MC27.10.2021
MK27.10.2021
MT27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
CY19.09.2024
FI19.09.2024
LU19.09.2024
PT19.03.2025
Former [2025/23]HU19.09.2016
AL27.10.2021
CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
MC27.10.2021
MK27.10.2021
MT27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
CY19.09.2024
FI19.09.2024
PT19.03.2025
Former [2025/21]HU19.09.2016
AL27.10.2021
CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
MC27.10.2021
MK27.10.2021
MT27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
FI19.09.2024
PT19.03.2025
Former [2024/42]HU19.09.2016
AL27.10.2021
CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
MC27.10.2021
MK27.10.2021
MT27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
Former [2024/27]HU19.09.2016
AL27.10.2021
CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
MC27.10.2021
MK27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
Former [2024/18]HU19.09.2016
AL27.10.2021
CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
MC27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
Former [2023/22]AL27.10.2021
CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
MC27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
Former [2022/49]AL27.10.2021
CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
Former [2022/35]CZ27.10.2021
EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
RO27.10.2021
RS27.10.2021
SK27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
Former [2022/34]EE27.10.2021
HR27.10.2021
LT27.10.2021
LV27.10.2021
RO27.10.2021
RS27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
Former [2022/33]HR27.10.2021
LT27.10.2021
LV27.10.2021
RS27.10.2021
SM27.10.2021
BG27.01.2022
IS27.02.2022
Former [2022/24]HR27.10.2021
LT27.10.2021
LV27.10.2021
RS27.10.2021
BG27.01.2022
IS27.02.2022
Former [2022/22]LT27.10.2021
RS27.10.2021
BG27.01.2022
Former [2022/21]RS27.10.2021
BG27.01.2022
Former [2022/19]BG27.01.2022
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DOI:   http://dx.doi.org/10.3390/molecules18077346
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