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EP3452448
European procedure
Extract from the Register of European Patents
EP About this file: EP3452448
| EP3452448 - MODULATORS OF THE INTEGRATED STRESS PATHWAY [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 25.10.2024 Database last updated on 01.04.2026 | |
| Former | The patent has been granted Status updated on 17.11.2023 | ||
| Former | Grant of patent is intended Status updated on 03.07.2023 | ||
| Former | Examination is in progress Status updated on 19.06.2023 | ||
| Former | Grant of patent is intended Status updated on 10.11.2022 | ||
| Former | Examination is in progress Status updated on 20.09.2022 | ||
| Former | Grant of patent is intended Status updated on 01.02.2022 | ||
| Former | Examination is in progress Status updated on 10.01.2022 | ||
| Former | Grant of patent is intended Status updated on 19.05.2021 | ||
| Former | Examination is in progress Status updated on 10.01.2020 | ||
| Former | Request for examination was made Status updated on 08.02.2019 | ||
| Former | The international publication has been made Status updated on 10.11.2017 | ||
| Former | unknown Status updated on 24.05.2017 | Most recent event Tooltip | 25.10.2024 | No opposition filed within time limit | published on 27.11.2024 [2024/48] | Applicant(s) | For all designated states Calico Life Sciences LLC 1170 Veterans Boulevard South San Francisco, CA 94080 / US | For all designated states AbbVie Inc. 1 North Waukegan Road North Chicago, IL 60064 / US | [2019/11] | Inventor(s) | 01 /
SIDRAUSKI, Carmela 20434 Walnut Ave Saratoga, CA 95070 / US | 02 /
PLIUSHCHEV, Marina 1834 Ridge Avenue Unit 108 Evanston, IL 60201 / US | 03 /
FROST, Jennifer, M. 635 Yorktown Lane Gumee, IL 60031 / US | 04 /
BLACK, Lawrence, A. 993 Green Meadow Avenue Vernon Hills, IL 60061 / US | 05 /
XU, Xiangdong 993 Green Meadow Avenue Vernon Hills, IL 60061 / US | 06 /
SWEIS, Ramzi, Farath 1012 Plaister Avenue Lake Bluff, IL 60044 / US | 07 /
SHI, Lei 1908 Trevino Terrace Vernon Hills, IL 60061 / US | 08 /
ZHANG, Qingwei 1820 S Falcon Drive Libertyville, IL 60048 / US | 09 /
TONG, Yunsong 1408 Braxton Road Libertyville, IL 60048 / US | 10 /
HUTCHINS, Charles, W. 31005 Prairie Ridge Road Green Oaks, IL 60048 / US | 11 /
CHUNG, Seungwon 1512 Virginia Avenue Libertyville, IL 60048 / US | 12 /
DART, Michael, J. 844 Yale Lane Highland Park, IL 60035 / US | [2021/26] |
| Former [2019/11] | 01 /
SIDRAUSKI, Carmela 20434 Walnut Ave Saratoga, CA 95070 / US | ||
| 02 /
PLIUSHCHEV, Marina 1834 Ridge Avenue Unit 108 Evanston, IL 60201 / US | |||
| 03 /
FROST, Jennifer, M. 635 Yorktown Lane Gumee, IL 60031 / US | |||
| 04 /
BLACK, Lawrence, A. 993 Green Meadow Avenue Vernon Hills, IL 60061 / US | |||
| 05 /
XU, Xiangdong 993 Green Meadow Avenue Vernon Hills, IL 60061 / US | |||
| 06 /
SWEIS, Ramzi, Farath 1012 Plaister Avenue Lake Bluff, IL 60044 / US | |||
| 07 /
SHI, Lei 1908 Trevino Terrace Vernon Hills, IL 60061 / US | |||
| 08 /
ZHANG, Qinwei, I. 1820 S Falcon Drive Libertyville, IL 60048 / US | |||
| 09 /
TONG, Yunsong 1408 Braxton Road Libertyville, IL 60048 / US | |||
| 10 /
HUTCHINS, Charles, W. 31005 Prairie Ridge Road Green Oaks, IL 60048 / US | |||
| 11 /
CHUNG, Seungwon 1512 Virginia Avenue Libertyville, IL 60048 / US | |||
| 12 /
DART, Michael, J. 844 Yale Lane Highland Park, IL 60035 / US | Representative(s) | Heller, Benjamin Henry, et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL / GB | [2019/11] | Application number, filing date | 17723899.5 | 05.05.2017 | [2019/11] | WO2017US31360 | Priority number, date | US201662332278P | 05.05.2016 Original published format: US 201662332278 P | [2019/11] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2017193034 | Date: | 09.11.2017 | Language: | EN | [2017/45] | Type: | A1 Application with search report | No.: | EP3452448 | Date: | 13.03.2019 | Language: | EN | The application published by WIPO in one of the EPO official languages on 09.11.2017 takes the place of the publication of the European patent application. | [2019/11] | Type: | B1 Patent specification | No.: | EP3452448 | Date: | 20.12.2023 | Language: | EN | [2023/51] | Search report(s) | International search report - published on: | EP | 09.11.2017 | Classification | IPC: | C07D213/73, C07D317/64, C07D231/56, C07D401/04, C07D237/14, C07D237/16, C07D405/08, C07D241/18, C07D471/04, C07D261/08, C07D261/20, C07C235/00, C07D271/113, C07D213/30, C07D213/64, C07D213/66, A61K31/44, A61P35/00 | [2019/11] | CPC: |
C07D471/04 (EP,IL,KR,RU,US);
A61K31/165 (IL);
A61K31/44 (IL,RU);
C07C235/22 (EP,IL,KR,US);
A61K31/167 (IL,KR);
A61P11/00 (IL);
A61P17/06 (IL);
A61P19/02 (IL);
A61P21/04 (IL);
A61P25/00 (IL);
A61P25/28 (EP,IL,KR,US);
A61P29/00 (IL,KR);
A61P3/00 (IL,KR);
A61P3/10 (IL);
A61P35/00 (IL,KR,RU);
A61P9/10 (IL);
C07C311/13 (EP,IL,KR,US);
C07C311/24 (EP,IL,KR,US);
C07C317/22 (EP,IL,US);
C07D213/30 (EP,IL,KR,US);
C07D213/64 (EP,IL,KR,US);
C07D213/66 (EP,IL,KR,US);
C07D213/73 (EP,IL,KR,RU,US);
C07D231/56 (EP,IL,KR,RU,US);
C07D237/14 (EP,IL,KR,RU,US);
C07D237/16 (EP,IL,KR,RU,US);
C07D241/18 (EP,IL,KR,RU,US);
C07D261/08 (EP,IL,KR,US);
C07D261/20 (EP,IL,KR,US);
C07D271/113 (EP,IL,KR,US);
C07D317/64 (EP,IL,KR,RU,US);
C07D401/04 (EP,IL,KR,RU,US);
C07D405/08 (EP,IL,KR,RU,US);
C07C2602/38 (EP,IL,KR,US);
C07C2602/40 (EP,IL,KR,US);
C07C2602/42 (EP,IL,KR,US);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/11] | Extension states | BA | 29.11.2018 | ME | 29.11.2018 | Validation states | MA | 29.11.2018 | MD | 29.11.2018 | Title | German: | MODULATOREN EINES INTEGRIERTEN SPANNUNGSWEGS | [2019/11] | English: | MODULATORS OF THE INTEGRATED STRESS PATHWAY | [2019/11] | French: | MODULATEURS DE LA VOIE DE RÉPONSE INTÉGRÉE AU STRESS | [2019/11] | Entry into regional phase | 29.11.2018 | National basic fee paid | 29.11.2018 | Designation fee(s) paid | 29.11.2018 | Examination fee paid | Examination procedure | 29.11.2018 | Examination requested [2019/11] | 29.11.2018 | Date on which the examining division has become responsible | 25.06.2019 | Amendment by applicant (claims and/or description) | 14.01.2020 | Despatch of a communication from the examining division (Time limit: M06) | 17.07.2020 | Reply to a communication from the examining division | 13.04.2021 | Cancellation of oral proceeding that was planned for 04.05.2021 | 04.05.2021 | Date of oral proceedings (cancelled) | 20.05.2021 | Communication of intention to grant the patent | 23.12.2021 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 02.02.2022 | Communication of intention to grant the patent | 13.09.2022 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 11.11.2022 | Communication of intention to grant the patent | 14.04.2023 | Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time | 16.06.2023 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 04.07.2023 | Communication of intention to grant the patent | 13.11.2023 | Fee for grant paid | 13.11.2023 | Fee for publishing/printing paid | 13.11.2023 | Receipt of the translation of the claim(s) | Divisional application(s) | EP23213609.3 / EP4356971 | Opposition(s) | 23.09.2024 | No opposition filed within time limit [2024/48] | Request for further processing for: | The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent | 16.06.2023 | Request for further processing filed | 16.06.2023 | Full payment received (date of receipt of payment) Request granted | 22.06.2023 | Decision despatched | The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent | 13.09.2022 | Request for further processing filed | 13.09.2022 | Full payment received (date of receipt of payment) Request granted | 26.09.2022 | Decision despatched | The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent | 23.12.2021 | Request for further processing filed | 23.12.2021 | Full payment received (date of receipt of payment) Request granted | 18.01.2022 | Decision despatched | Fees paid | Renewal fee | 08.05.2019 | Renewal fee patent year 03 | 27.05.2020 | Renewal fee patent year 04 | 27.05.2021 | Renewal fee patent year 05 | 27.05.2022 | Renewal fee patent year 06 | 30.05.2023 | Renewal fee patent year 07 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [I] US2016096800 (WALTER PETER et al.) | [X] US2007185079 (EVERTSSON EMMA et al.) | [X] US7994211 (RAY NICHOLAS CHARLES et al.) | [X] US2015057289 (LI GUIYING et al.) | [X] DATABASE PubChem Compound [online] 23 March 2015 (2015-03-23), XP002770920, retrieved from NCBI Database accession no. 91663862 | [X] DATABASE PubChem Compound [online] 15 November 2010 (2010-11-15), XP002770921, retrieved from NCBI Database accession no. 46939935 | [X] DATABASE PubChem Compound [online] 15 November 2010 (2010-11-15), XP002770922, retrieved from NCBI Database accession no. 46939936 | [X] DATABASE PubChem Compound [online] 3 May 2011 (2011-05-03), XP002770923, retrieved from NCBI Database accession no. 51064332 | [X] DATABASE PubChem Compound [online] 30 November 2012 (2012-11-30), XP002770924, Database accession no. 68048074 | [X] DATABASE PubChem Compound [online] 23 February 2016 (2016-02-23), XP002770925, retrieved from NCBI Database accession no. 118417886 | Examination | ALBRECHT BERKESSEL ET AL: "Chemically Induced Cardiomyogenesis of Mouse Embryonic Stem Cells", CHEMBIOCHEM, vol. 11, no. 2, 25 January 2010 (2010-01-25), pages 208 - 217, XP055655243, ISSN: 1439-4227, DOI: 10.1002/cbic.200900345 DOI: http://dx.doi.org/10.1002/cbic.200900345 | by applicant | US4911920 | US5403841 | US5212 | US162 | US4861760 | WEK, R.C. ET AL., BIOCHEM SOC TRANS, vol. 34, 2006, pages 7 - 11 | HINNEBUSCH, A.G.; LORSCH, J.R., COLD SPRING HARBOR PERSPECT BIOL, vol. 4, no. 10, 2012 | KRISHNAMOORTHY, T. ET AL., MOL CELL BIOL, vol. 21, no. 15, 2001, pages 5018 - 5030 | WILLIAMS, D.D. ET AL., J BIOL CHEM, vol. 276, 2001, pages 24697 - 24703 | DEV, K. ET AL., MOL CELL BIOL, vol. 30, 2010, pages 5218 - 5233 | GORDIYENKO, Y. ET AL., NAT COMMUN, vol. 5, 2014, pages 3902 | WORTHAM, N.C. ET AL., FASEB J, vol. 28, 2014, pages 2225 - 2237 | SIDRAUSKI, C. ET AL., ELIFE, 2015, pages E07314 | SEKINE, Y. ET AL., SCIENCE, vol. 348, 2015, pages 1027 - 1030 | "Handbook of Chemistry and Physics" | THOMAS SORRELL: "Organic Chemistry", 1999, UNIVERSITY SCIENCE BOOKS | SMITH; MARCH: "March's Advanced Organic Chemistry", 2001, JOHN WILEY & SONS, INC | LAROCK: "Comprehensive Organic Transformations", 1989, VCH PUBLISHERS, INC. | CARRUTHERS: "Some Modern Methods of Organic Synthesis", 1987, CAMBRIDGE UNIVERSITY PRESS | JACQUES ET AL.: "Enantiomers, Racemates and Resolutions", 1981, WILEY INTERSCIENCE | WILEN ET AL., TETRAHEDRON, vol. 33, 1977, pages 2725 | ELIEL: "Stereochemistry of Carbon Compounds", 1962, MCGRAW-HILL | WILEN: "Tables of Resolving Agents and Optical Resolutions", 1972, UNIV. OF NOTRE DAME PRESS, pages: 268 | BERGE ET AL., JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 66, 1977, pages 1 - 19 | LIEBERMAN, PHARMACEUTICAL DOSAGE FORMS, vol. 1-3, 1992 | LLOYD, THE ART, SCIENCE AND TECHNOLOGY OF PHARMACEUTICAL COMPOUNDING, 1999 | PICKAR, DOSAGE CALCULATIONS, 1999 | "Remington: The Science and Practice of Pharmacy", 2003, LIPPINCOTT, WILLIAMS & WILKINS | RAO, J., BIOMATER SCI. POLYM. ED., vol. 7, 1995, pages 623 - 645 | GAO PHARM. RES., vol. 12, 1995, pages 857 - 863 | EYLES, J. PHARM. PHARMACOL., vol. 49, 1997, pages 669 - 674 | AL-MUHAMMED, J. MICROENCAPSUL., vol. 13, 1996, pages 293 - 306 | CHONN, CURR. OPIN. BIOTECHNOL., vol. 6, 1995, pages 698 - 708 | OSTRO, J., HOSP. PHARM., vol. 46, 1989, pages 1576 - 1587 | GREENE ET AL.: "Protecting Groups in Organic Synthesis", 1991, WILEY |