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Extract from the Register of European Patents

EP About this file: EP3612236

EP3612236 - COMBINATION THERAPY WITH AN ANTI-CD25 ANTIBODY-DRUG CONJUGATE [Right-click to bookmark this link]
StatusGrant of patent is intended
Status updated on  16.10.2023
Database last updated on 24.04.2024
FormerExamination is in progress
Status updated on  06.05.2022
FormerRequest for examination was made
Status updated on  24.01.2020
FormerThe international publication has been made
Status updated on  27.10.2018
Formerunknown
Status updated on  08.05.2018
Most recent event   Tooltip21.03.2024New entry: Application deemed to be withdrawn: despatch of communication + time limit 
Applicant(s)For all designated states
ADC Therapeutics SA
Biopôle
Route de la Corniche 3B
1066 Epalinges / CH
For all designated states
Medimmune Limited
Milstein Building Granta Park
Cambridge, Cambridgeshire CB21 6GH / GB
[2020/09]
Inventor(s)01 / VAN BERKEL, Patricius Hendrikus Cornelis
c/o ADC Therapeutics SA
Biopôle route de la Corniche 3b
1066 Epalinges / CH
02 / SKELTON, Lisa
c/o ADC Therapeutics SA
Biopôle route de la Corniche 3b
1066 Epalinges / CH
03 / ZAMMARCHI, Francesca
c/o ADC Therapeutics SA
Biopôle route de la Corniche 3b
1066 Epalinges / CH
04 / FEINGOLD, Jay Marshall
c/o ADC Therapeutics Americas
430 Mountain Ave. 4th Floor
Murray Hill New Jersey 07947 / US
05 / WUERTHNER, Jens
c/o ADC Therapeutics SA
Biopôle route de la Corniche 3b
1066 Epalinges / CH
06 / HARTLEY, John
c/o University College London
Gower Street
London WC1E 6BT / GB
 [2020/09]
Representative(s)Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
[N/P]
Former [2020/09]Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
Application number, filing date18719542.520.04.2018
[2020/09]
WO2018EP60214
Priority number, dateGB2017000625220.04.2017         Original published format: GB 201706252
GB2017000625120.04.2017         Original published format: GB 201706251
GB2017000625020.04.2017         Original published format: GB 201706250
GB2017000624920.04.2017         Original published format: GB 201706249
GB2017000624820.04.2017         Original published format: GB 201706248
GB2017000624720.04.2017         Original published format: GB 201706247
GB2017000624620.04.2017         Original published format: GB 201706246
GB2017000624520.04.2017         Original published format: GB 201706245
GB2018000518929.03.2018         Original published format: GB 201805189
[2020/09]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018193104
Date:25.10.2018
Language:EN
[2018/43]
Type: A1 Application with search report 
No.:EP3612236
Date:26.02.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 25.10.2018 takes the place of the publication of the European patent application.
[2020/09]
Search report(s)International search report - published on:EP25.10.2018
ClassificationIPC:A61K47/68, A61K31/7068, A61K39/395, A61K45/06, A61P35/00, A61P35/02, C07K16/24, C07K16/28
[2023/44]
CPC:
A61K47/6803 (EP,KR,US); A61K47/6849 (EP,KR,US); A61K31/5517 (US);
A61K31/706 (KR); A61K31/7068 (EP,KR,US); A61K31/7076 (KR,US);
A61K39/3955 (EP); A61K39/39558 (KR); A61K45/06 (EP,KR);
A61P35/00 (EP,KR); A61P35/02 (EP,KR); C07K16/241 (EP,KR);
C07K16/2818 (EP,KR,US); C07K16/2827 (US); C07K16/2878 (US);
A61K2039/505 (EP,KR); A61K2300/00 (KR); C07K2317/76 (EP,KR) (-)
C-Set:
A61K31/7068, A61K2300/00 (EP);
A61K39/3955, A61K2300/00 (EP)
Former IPC [2020/09]A61K47/68, A61K31/7068, A61K45/06, A61P35/00, A61P35/02
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/09]
TitleGerman:KOMBINATIONSTHERAPIE MIT EINEM ANTI-CD25-ANTIKÖRPER-ARZNEIMITTELKONJUGAT[2020/09]
English:COMBINATION THERAPY WITH AN ANTI-CD25 ANTIBODY-DRUG CONJUGATE[2020/09]
French:POLYTHÉRAPIE AVEC UN CONJUGUÉ ANTICORPS-MÉDICAMENT ANTI-CD25[2020/09]
Entry into regional phase01.11.2019National basic fee paid 
01.11.2019Designation fee(s) paid 
01.11.2019Examination fee paid 
Examination procedure01.11.2019Examination requested  [2020/09]
01.11.2019Date on which the examining division has become responsible
25.09.2020Amendment by applicant (claims and/or description)
09.05.2022Despatch of a communication from the examining division (Time limit: M04)
13.09.2022Reply to a communication from the examining division
17.10.2023Communication of intention to grant the patent
20.03.2024Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time
Request for further processing for:25.09.2020Request for further processing filed
25.09.2020Full payment received (date of receipt of payment)
Request granted
07.10.2020Decision despatched
Fees paidRenewal fee
29.04.2020Renewal fee patent year 03
21.04.2021Renewal fee patent year 04
23.03.2022Renewal fee patent year 05
19.04.2023Renewal fee patent year 06
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Rights in Rem or Legal Means of ExecutionID:01
For:AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Date:24.06.2020
ID:02
For:AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Date:07.10.2022
[2023/01]
Former [2020/47]ID:01
For:AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Date:24.06.2020
[2023/01]
Cited inInternational search[XY]WO2014057119  (ADC THERAPEUTICS S RL [CH]) [X] 1-17,20-25,36-41 * page 13, line 26 - page 15, line 35 * * page 84, line 4 - page 87, line 21 * * page 88, lines 25-26 * * page 167, line 30 - page 168, line 12 * * page 169, line 20 - page 173, line 12 * * claims 1,2,100,101,103,109-117 * * page 194, lines 1-10 * * figures 3A,3C,4,5 * [Y] 1-42;
 [XY]WO2016177438  (ADC THERAPEUTICS SA [CH]) [X] 1-25,36-41 * page 3, lines 25-29 * * page 71; compound ConjE * * page 84, line 33 - page 88, line 16 * * page 89, lines 20,21 * * page 105, line 15 - page 106, line 29 * * page 108, line 4 - page 112, line 10 * * claims 1,99,103,105,107,111,113,115-124 * * figures 1-6 * [Y] 1-42;
 [Y]  - M. J. FLYNN ET AL, "ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody-Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies", MOLECULAR CANCER THERAPEUTICS, US, (20161101), vol. 15, no. 11, doi:10.1158/1535-7163.MCT-16-0233, ISSN 1535-7163, pages 2709 - 2721, XP055488025 [Y] 1-42 * abstract * * figure 1A * * page 2717, column r, paragraph 2 - page 2720, column l, line 22 *

DOI:   http://dx.doi.org/10.1158/1535-7163.MCT-16-0233
 [Y]  - SMITHA MENON ET AL, "Advances in Cancer Immunotherapy in Solid Tumors", CANCERS, (20161124), vol. 8, no. 12, doi:10.3390/cancers8120106, pages 1 - 21, XP055488463 [Y] 1-42 * abstract * * table 1 * * page 6, paragraphs 1,2 * * page 12, paragraph 4 - page 15, paragraph 4 *

DOI:   http://dx.doi.org/10.3390/cancers8120106
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.