blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP3816300

EP3816300 - CONJUNCTIVAL DISEASE DETECTION METHOD USING OCULAR SURFACE TISSUE, AND BIOMARKER FOR AGING [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  03.04.2021
Database last updated on 24.04.2024
FormerThe international publication has been made
Status updated on  03.01.2020
Most recent event   Tooltip28.06.2023New entry: Renewal fee paid 
Applicant(s)For all designated states
Osaka University
1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
For all designated states
Otsuka Pharmaceutical Co., Ltd.
2-9, Kanda Tsukasa-machi
Chiyoda-ku
Tokyo 101-8535 / JP
[2021/18]
Inventor(s)01 / NISHIDA Kohji
c/o OSAKA UNIVERSITY, 1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
02 / HASHIDA Noriyasu
c/o OSAKA UNIVERSITY, 1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
03 / IIDA Tetsuya
c/o OSAKA UNIVERSITY, 1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
04 / NAKAMURA Shota
c/o OSAKA UNIVERSITY, 1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
05 / MOTOOKA Daisuke
c/o OSAKA UNIVERSITY, 1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
06 / ASAO Kazunobu
c/o OSAKA UNIVERSITY, 1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
07 / ANDO Satoru
c/o Otsuka Pharmaceutical Co., Ltd., 3-2-27,
Otedori, Chuo-ku
Osaka-shi, Osaka 540-0021 / JP
 [2021/18]
Representative(s)dompatent von Kreisler Selting Werner - Partnerschaft von Patent- und Rechtsanwälten mbB
Deichmannhaus am Dom
Bahnhofsvorplatz 1
50667 Köln / DE
[2021/18]
Application number, filing date19825086.228.06.2019
[2021/18]
WO2019JP25827
Priority number, dateJP2018012450429.06.2018         Original published format: JP 2018124504
[2021/18]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020004626
Date:02.01.2020
Language:JA
[2020/01]
Type: A1 Application with search report 
No.:EP3816300
Date:05.05.2021
Language:EN
[2021/18]
Search report(s)International search report - published on:JP02.01.2020
(Supplementary) European search report - dispatched on:EP14.02.2022
ClassificationIPC:C12Q1/6876, C12Q1/6883, C12Q1/6886, C12Q1/689
[2022/11]
CPC:
C12Q1/689 (EP,US); C12Q1/06 (US); C12Q1/6876 (EP);
C12Q1/6883 (EP); C12Q1/6886 (EP)
Former IPC [2021/18]C12Q1/6806, C12N15/31, C12Q1/6869, G01N33/48, G01N33/50
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/18]
TitleGerman:VERFAHREN ZUR DETEKTION VON BINDEHAUTERKRANKUNGEN UNTER VERWENDUNG VON AUGENOBERFLÄCHENGEWEBE UND BIOMARKER FÜR ALTERUNG[2021/18]
English:CONJUNCTIVAL DISEASE DETECTION METHOD USING OCULAR SURFACE TISSUE, AND BIOMARKER FOR AGING[2021/18]
French:PROCÉDÉ DE DÉTECTION DE MALADIE CONJONCTIVALE UTILISANT DU TISSU DE SURFACE OCULAIRE ET BIOMARQUEUR DE VIEILLISSEMENT[2021/18]
Entry into regional phase18.12.2020Translation filed 
18.12.2020National basic fee paid 
18.12.2020Search fee paid 
18.12.2020Designation fee(s) paid 
18.12.2020Examination fee paid 
Examination procedure18.12.2020Examination requested  [2021/18]
06.09.2022Amendment by applicant (claims and/or description)
Fees paidRenewal fee
28.06.2021Renewal fee patent year 03
28.06.2022Renewal fee patent year 04
28.06.2023Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]WO2012118535  (QUORUM INNOVATIONS LLC [US], et al) [A] 1-9 * the whole document *;
 [A]WO2017170571  (UNIV OSAKA [JP]) [A] 1-9* the whole document *;
 [X]  - YANJIAO ZHOU ET AL, "The conjunctival microbiome in health and trachomatous disease: a case control study", GENOME MEDICINE,, (20141115), vol. 6, no. 11, doi:10.1186/S13073-014-0099-X, ISSN 1756-994X, page 99, XP021206547 [X] 1,6-9 * abstract; p. 2, right-hand col., 1st-2nd full para.; p. 4, left-hand col., 1st full para.; fig. 2A; table 2: group 1 *

DOI:   http://dx.doi.org/10.1186/s13073-014-0099-x
 [X]  - RUMI AOKI ET AL, "Identification of Causative Pathogens in Eyes with Bacterial Conjunctivitis by Bacterial Cell Count and Microbiota Analysis", OPHTHALMOLOGY, AMSTERDAM, NL, (20130401), doi:10.1016/j.ophtha.2012.10.001, ISSN 0161-6420, pages 668 - 676, XP055673107 [X] 1,6 * abstract; p. 73, left-hand col., 1st-3rd para. *

DOI:   http://dx.doi.org/10.1016/j.ophtha.2012.10.001
 [X]  - JOANNA E. GRAHAM ET AL, "Ocular Pathogen or Commensal: A PCR-Based Study of Surface Bacterial Flora in Normal and Dry Eyes", INVESTIGATIVE OPTHALMOLOGY & VISUAL SCIENCE, US, (20071201), vol. 48, no. 12, doi:10.1167/iovs.07-0588, ISSN 1552-5783, page 5616, XP055360531 [X] 1,6 * abstract *

DOI:   http://dx.doi.org/10.1167/iovs.07-0588
 [X]  - THIEL H J ET AL, "Über die Standortflora der menschlichen Bindehaut: Untersuchungen von 135 Personen unterschiedlichen Alters", KLIN MONBL AUGENHEILKD, vol. 205, no. 12, doi:10.1055/s-2008-1045542, (19941201), pages 348 - 357, URL: https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-2008-1045542, XP055886681 [X] 7,9 * abstract *

DOI:   http://dx.doi.org/10.1055/s-2008-1045542
 [XI]  - FRANCESCA COLLINA ET AL, "Chlamydia psittaci in ocular adnexa MALT lymphoma: a possible role in lymphomagenesis and a different geographical distribution", INFECTIOUS AGENTS AND CANCER, BIOMED CENTRAL LTD, LO, (20120402), vol. 7, no. 1, doi:10.1186/1750-9378-7-8, ISSN 1750-9378, page 8, XP021125536 [X] 1,2 * abstract * [I] 3-6

DOI:   http://dx.doi.org/10.1186/1750-9378-7-8
 [XP]  - KAZUNOBU ASAO ET AL, "Conjunctival dysbiosis in mucosa-associated lymphoid tissue lymphoma", SCIENTIFIC REPORTS, (20190610), vol. 9, no. 1, doi:10.1038/s41598-019-44861-5, pages 1 - 10, XP055673150 [XP] 1-6 * the whole document *

DOI:   http://dx.doi.org/10.1038/s41598-019-44861-5
 [A]  - DONG QUNFENG ET AL, "Diversity of Bacteria at Healthy Human Conjunctiva", INVESTIGATIVE OPTHALMOLOGY & VISUAL SCIENCE, US, (20110720), vol. 52, no. 8, doi:10.1167/iovs.10-6939, ISSN 1552-5783, page 5408, XP055886390 [A] 1-9 * the whole document *

DOI:   http://dx.doi.org/10.1167/iovs.10-6939
International search[X]JP2015188379  (MORINAGA MILK INDUSTRY CO LTD) [X] 7-9 * , *;
 [XYA]JP2016525355  [X] 1, 3, 5-6 * , * [Y] 1, 6 [A] 2, 4;
 [X]WO2017014256  (TAK-CIRCULATOR CO LTD [JP], et al) [X] 7, 9 * , *;
 [YA]  - ZHOU YANJIAO et al., "The conjunctival microbiome in health and trachomatous disease: a case control study", Genome Medicine, (20140000), vol. 6, doi:10.1186/s13073-014-0099-x, XP021206547 [Y] 1, 6 [A] 2-5

DOI:   http://dx.doi.org/10.1186/s13073-014-0099-x
 [YA]  - AOKI RUMI et al., "Identification of Causative Pathogens in Eyes with Bacterial Conjunctivitis by Bacterial Cell Count and Microbiota Analysis", Ophthalmology, (20130000), vol. 120, no. 4, pages 668 - 676, XP055673107 [Y] 1, 6 [A] 2-5

DOI:   http://dx.doi.org/10.1016/j.ophtha.2012.10.001
 [X]  - SHIBAGAKI NAKAKO et al., "Aging-related changes in the diversity of women's skin microbiomes associated with oral bacteria", Scientific Reports, (20170000), vol. 7, doi:10.1038/s41598-017-10834-9, XP055554307 [X] 7-9

DOI:   http://dx.doi.org/10.1038/s41598-017-10834-9
 [PX]  - ASAO KAZUNOBU et al., "Conjunctival dysbiosis in mucosa-associated lymphoid tissue lymphoma", Scientific Reports, (20190000), vol. 9, pages 1 - 10, XP055673150 [PX] 1-6

DOI:   http://dx.doi.org/10.1038/s41598-019-44861-5
 [PX]  - JUGE R. et al., "Shift in skin microbiota of Western European women across aging", Journal of Applied Microbiology, (20180900), vol. 125, no. 3, doi:10.1111/jam.13929, pages 907 - 916, XP055554331 [PX] 7-9

DOI:   http://dx.doi.org/10.1111/jam.13929
by applicantJP2017029133
    - MAHMOOD S et al., J. Clin. Microbiol., (20120000), vol. 50, no. 11, pages 3799 - 3800
    - SABINE LEIBELING et al., Environ. Sci. Technol., (20100000), vol. 44, no. 10, pages 3793 - 3799
    - ABBY L. GEIS et al., Cancer Discov., vol. 5, no. 10, pages 1098 - 1109
    - ROL N et al., J. Biol. Chem., (20120000), vol. 287, no. 47, pages 40074 - 40082
    - SARA OMENETTI et al., Front. Immunol., (20150000), vol. 6
    - TAYLOR FEEHLEY et al., Curr. Opin. Lmmunol., (20140000), vol. 31, pages 79 - 86
    - OUWEHAND AC et al., World J. Gastroenterol., (20090000), vol. 15, no. 26, pages 3261 - 3268
    - STEFKA AT et al., Proc. Natl. Acad. Sci. USA, vol. 111, no. 36, pages 13145 - 13150
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.