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EP3757128
European procedure
Extract from the Register of European Patents
EP About this file: EP3757128
| EP3757128 - CHIMERIC ANTIGEN RECEPTORS TARGETING B-CELL MATURATION ANTIGEN [Right-click to bookmark this link] | Status | The patent has been granted Status updated on 09.05.2025 Database last updated on 31.03.2026 | |
| Former | Grant of patent is intended Status updated on 30.01.2025 | ||
| Former | Examination is in progress Status updated on 11.01.2025 | ||
| Former | Grant of patent is intended Status updated on 26.09.2024 | ||
| Former | Examination is in progress Status updated on 26.08.2022 | ||
| Former | Request for examination was made Status updated on 25.06.2021 | ||
| Former | The application has been published Status updated on 27.11.2020 | Most recent event Tooltip | 10.03.2026 | Change - representative | Applicant(s) | For all designated states Pfizer Inc. 66 Hudson Boulevard East New York, NY 10001-2192 / US | [2023/18] |
| Former [2021/01] | For all designated states Pfizer Inc. 235 East 42nd Street New York, NY 10017 / US | Inventor(s) | 01 /
KUO, Tracy Chia-Chien 120 Windsor Court San Carlos, California 94070 / US | 02 /
CHAPARRO RIGGERS, Javier Fernando 816 North Delaware Street, Apt. 411 San Mateo, CA 94401 / US | 03 /
SASU, Barbra Johnson 2125 Bryant Street, 316 San Francisco, California 94110 / US | 04 /
GALETTO, Roman 12 Rue Ernest Cresson 75014 Paris / FR | 05 /
BOLDAJIPOUR, Bijan Andre 860 14th Street, Apt. 3 San Francisco, California 94114 / US | 06 /
SOMMER, Cesar Adolfo 155 N El Camino Real, Apt. 31 San Mateo, California 94401 / US | 07 /
VAN BLARCOM, Thomas John 6415 Chelton Drive Oakland, California 94611 / US | 08 /
PERTEL, Thomas Charles 29 Creekridge Court San Mateo, California 94402 / US | 09 /
RAJPAL, Arvind 150 Granville Way San Francisco, CA 94127 / US | 10 /
DUCHATEAU, Philippe 10bis route de Quillan 11500 Saint Louis et Parahou / FR | 11 /
JUILLERAT, Alexandre 444 East 82nd Street, 5A New York, New York 10028 / US | 12 /
VALTON, Julien 19 rue Victor Hugo 94220 Charenton le Pont / FR | [2024/44] |
| Former [2021/01] | 01 /
KUO, Tracy Chia-Chien 120 Windsor Court San Carlos, California 94070 / US | ||
| 02 /
CHAPARRO RIGGERS, Javier Fernando 816 North Delaware Street, Apt. 411 San Mateo, CA 94401 / US | |||
| 03 /
SASU, Barbra Johnson 2125 Bryant Street, 316 San Francisco, California 94110 / US | |||
| 04 /
GALETTO, Roman 12 Rue Ernest Cresson 75014 Paris / FR | |||
| 05 /
BOLDAJIPOUR, Bijan Andre 860 14th Street, Apt. 3 San Francisco, California 94114 / US | |||
| 06 /
SOMMER, Cesar Adolfo 155 N El Camino Real, Apt. 31 San Mateo, California 94401 / US | |||
| 07 /
VAN BLARCOM, Thomas John 6415 Chelton Drive Oakland, California 94611 / US | |||
| 08 /
PERTEL, Thomas Charles 29 Creekridge Court San Mateo, California 94402 / US | |||
| 09 /
RAJPAL, Arvind 150 Granville Way San Francisco, CA 94127 / US | |||
| 10 /
DUCHATEAU, Philippe 10bis route de Quillan 11500 Saint Louis et Parahou / FR | |||
| 11 /
JUILLERAT, Alexandre 444 East 82nd Street, 5A New York, New York 10028 / FR | |||
| 12 /
VALTON, Julien 19 rue Victor Hugo 94220 Charenton le Pont / FR | Representative(s) | Goodwin Procter (UK) LLP Sancroft, 10-15 Newgate Street EC1A 7AZ / London / GB | [N/P] |
| Former [2025/24] | Cooley (UK) LLP 22 Bishopsgate London EC2N 4BQ / GB | ||
| Former [2021/01] | Cooley (UK) LLP Dashwood 69 Old Broad Street London EC2M 1QS / GB | Application number, filing date | 20172811.0 | 30.03.2016 | [2021/01] | Priority number, date | US201562146825P | 13.04.2015 Original published format: US 201562146825 P | US201662286473P | 25.01.2016 Original published format: US 201662286473 P | US201662301177P | 29.02.2016 Original published format: US 201662301177 P | [2021/01] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP3757128 | Date: | 30.12.2020 | Language: | EN | [2020/53] | Type: | B1 Patent specification | No.: | EP3757128 | Date: | 11.06.2025 | Language: | EN | [2025/24] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 06.11.2020 | Classification | IPC: | C07K16/28, A61K35/17, C07K19/00, A61K39/395, A61P35/00 | [2021/01] | CPC: |
C07K16/2878 (EP,IL,KR,RU,US);
A61K31/7076 (EP,IL,RU,US);
C07K14/7051 (EP,CN,IL,KR,RU,US);
A61K35/17 (IL);
A61K38/00 (EP,IL,RU,US);
A61K39/0011 (IL);
A61K40/00 (US);
A61K40/11 (EP,CN,KR,RU,US);
A61K40/13 (KR);
A61K40/31 (EP,CN,KR,RU,US);
A61K40/4215 (EP,CN,RU,US);
A61P35/00 (EP,CN,IL,KR);
A61P35/02 (EP,IL);
A61P37/04 (EP,IL);
C07K14/70517 (EP,IL,RU,US);
C07K14/70578 (EP,IL,RU,US);
C07K16/28 (CN);
C07K16/2863 (IL,RU,US);
C07K16/2896 (IL,RU,US);
C12N15/63 (IL,RU,US);
C12N15/85 (CN);
C12N5/0636 (EP,CN,IL,RU,US);
C12N5/0646 (EP,CN,RU,US);
C12N5/10 (IL,US);
A61K2039/505 (EP,IL,US);
A61K2039/5156 (IL);
A61K2121/00 (KR);
A61K2239/38 (EP,CN,RU,US);
A61K2239/48 (EP,CN,RU,US);
A61K2300/00 (KR);
C07K2317/56 (EP,CN,IL,US);
C07K2317/565 (CN,IL,US);
C07K2317/569 (IL,US);
C07K2317/622 (EP,IL,US);
C07K2317/73 (EP,IL,US);
C07K2317/92 (EP,IL,KR,US);
C07K2319/02 (EP,CN,IL,KR,US);
C07K2319/03 (EP,CN,IL,KR,US);
C07K2319/33 (EP,IL,US);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2021/30] |
| Former [2021/01] | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR | Title | German: | CHIMÄRE ANTIGENREZEPTOREN ZUM TARGETING DES B-ZELL-REIFUNGSANTIGENS | [2021/01] | English: | CHIMERIC ANTIGEN RECEPTORS TARGETING B-CELL MATURATION ANTIGEN | [2021/01] | French: | RÉCEPTEURS ANTIGÉNIQUES CHIMÉRIQUES CIBLANT L'ANTIGÈNE DE MATURATION DES CELLULES B | [2021/01] | Biological material | This application mentions deposited biological material, check the file for details | Examination procedure | 18.06.2021 | Amendment by applicant (claims and/or description) | 18.06.2021 | Examination requested [2021/30] | 18.06.2021 | Date on which the examining division has become responsible | 25.08.2022 | Despatch of a communication from the examining division (Time limit: M06) | 02.03.2023 | Reply to a communication from the examining division | 27.09.2024 | Communication of intention to grant the patent | 08.01.2025 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 31.01.2025 | Communication of intention to grant the patent | 07.05.2025 | Fee for grant paid | 07.05.2025 | Fee for publishing/printing paid | 07.05.2025 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP16714020.1 / EP3283520 | Fees paid | Renewal fee | 17.08.2020 | Renewal fee patent year 03 | 17.08.2020 | Renewal fee patent year 04 | 17.08.2020 | Renewal fee patent year 05 | 12.03.2021 | Renewal fee patent year 06 | 14.02.2022 | Renewal fee patent year 07 | 14.02.2023 | Renewal fee patent year 08 | 03.01.2024 | Renewal fee patent year 09 | 06.01.2025 | Renewal fee patent year 10 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | AT | 11.06.2025 | BG | 11.06.2025 | CZ | 11.06.2025 | EE | 11.06.2025 | FI | 11.06.2025 | HR | 11.06.2025 | LV | 11.06.2025 | NL | 11.06.2025 | PL | 11.06.2025 | RO | 11.06.2025 | SK | 11.06.2025 | SM | 11.06.2025 | NO | 11.09.2025 | RS | 11.09.2025 | GR | 12.09.2025 | IS | 11.10.2025 | PT | 13.10.2025 | [2026/10] |
| Former [2026/09] | AT | 11.06.2025 | |
| BG | 11.06.2025 | ||
| CZ | 11.06.2025 | ||
| FI | 11.06.2025 | ||
| HR | 11.06.2025 | ||
| LV | 11.06.2025 | ||
| NL | 11.06.2025 | ||
| SM | 11.06.2025 | ||
| NO | 11.09.2025 | ||
| RS | 11.09.2025 | ||
| GR | 12.09.2025 | ||
| IS | 11.10.2025 | ||
| PT | 13.10.2025 | ||
| Former [2026/08] | AT | 11.06.2025 | |
| BG | 11.06.2025 | ||
| FI | 11.06.2025 | ||
| HR | 11.06.2025 | ||
| LV | 11.06.2025 | ||
| NL | 11.06.2025 | ||
| SM | 11.06.2025 | ||
| NO | 11.09.2025 | ||
| RS | 11.09.2025 | ||
| GR | 12.09.2025 | ||
| IS | 11.10.2025 | ||
| PT | 13.10.2025 | ||
| Former [2026/07] | BG | 11.06.2025 | |
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| LV | 11.06.2025 | ||
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| GR | 12.09.2025 | ||
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| PT | 13.10.2025 | ||
| Former [2026/03] | BG | 11.06.2025 | |
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| PT | 13.10.2025 | ||
| Former [2025/52] | BG | 11.06.2025 | |
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| Former [2025/49] | BG | 11.06.2025 | |
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| NO | 11.09.2025 | ||
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| GR | 12.09.2025 | ||
| Former [2025/48] | BG | 11.06.2025 | |
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| NO | 11.09.2025 | ||
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| Former [2025/47] | BG | 11.06.2025 | |
| FI | 11.06.2025 | ||
| NO | 11.09.2025 | ||
| GR | 12.09.2025 | ||
| Former [2025/46] | FI | 11.06.2025 | Documents cited: | Search | [XYI] WO2013154760 (US HEALTH et al.) | [Y] WO2014152177 (ANTHROGENESIS CORP et al.) | [XP] WO2015158671 (CELLECTIS et al.) | [XP] WO2016014565 (NOVARTIS AG et al.) | [Y] TORIKAI HIROKI ET AL: "A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, UNITED STATES, vol. 119, no. 24, 14 June 2012 (2012-06-14), pages 5697 - 5705, XP002752739, ISSN: 1528-0020 DOI: http://dx.doi.org/10.1182/blood-2012-01-405365 | by applicant | US4816567 | WO9958572 | US5545807 | US5545806 | US5569825 | US5625126 | US5633425 | US5661016 | US5750373 | US4683195 | US4800159 | US4754065 | US4683202 | WO8704462 | US5037743 | US5143830 | WO2014039523 | WO2014184741 | WO2014191128 | WO2014184744 | WO2014184143 | WO2012058458 | US6352694 | US6534055 | US6905680 | US6692964 | US5858358 | US6887466 | US6905681 | US7144575 | US7067318 | US7172869 | US7232566 | US7175843 | US5883223 | US6905874 | US6797514 | US6867041 | US2006121005 | WO2013153391 | LONIAL ET AL., CLINICAL CANCER RES., vol. 77, no. 6, 2011, pages 1264 - 1277 | RAJKUMAR, NATURE REV. CLINICAL ONCOL, vol. 5, no. 8, 2011, pages 479 - 491 | BRENNER ET AL., CURRENT OPINION IN IMMUNOLOGY, vol. 22, no. 2, 2010, pages 251 - 257 | ROSENBERG ET AL., NATURE REVIEWS CANCER, vol. 8, no. 4, 2008, pages 299 - 308 | ESHHAR ET AL., PROC. NATL. ACAD. SCI. USA, vol. 90, no. 2, 1993, pages 720 - 724 | SADELAIN ET AL., CURR. OPIN. IMMUNOL, vol. 21, no. 2, 2009, pages 215 - 223 | CHOTHIA ET AL., NATURE, vol. 342, 1989, pages 877 - 883 | "Oligonucleotide Synthesis", 1984 | SHEETS ET AL., PROC. NATL. ACAD. SCI. (USA, vol. 95, 1998, pages 6157 - 6162 | SANTOU, N.NES, M., MOL. BIOL. EVOL., vol. 4, 1987, pages 406 - 425 | "Cell and Tissue Culture: Laboratory Procedures", 1993, J. WILEY AND SONS | CAPEL ET AL., IMMUNOMETHODS, vol. 4, 1994, pages 25 - 34 | RAVETCHKINET, ANN. REV. IMMUNOL., vol. 9, 1991, pages 457 - 92 | JAYASENA, S.D., CLIN. CHEM., vol. 45, 1999, pages 1628 - 50 | P. FINCH, ANTIBODIES, 1997 | BIRD ET AL., SCIENCE, vol. 242, 1988, pages 423 - 426 | "Monoclonal antibodies: a practical approach", 2000, OXFORD UNIVERSITY PRESS | DE HAAS ET AL., J. LAB. CLIN. MED., vol. 126, 1995, pages 330 - 41 | AL-LAZIKANI ET AL., J. MOLEC. BIOL., vol. 273, 1997, pages 927 - 948 | MACCALLUM ET AL., J. MOL. BIOL., vol. 262, 1996, pages 732 - 745 | MAKABE ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 283, 2008, pages 1156 - 1166 | KOHLERMILSTEIN, NATURE, vol. 256, 1975, pages 495 | MCCAFFERTY ET AL., NATURE, vol. 348, 1990, pages 552 - 554 | VAUGHAN ET AL., NATURE BIOTECHNOLOGY, vol. 14, 1996, pages 309 - 314 | HOOGENBOOMWINTER, J. MOL. BIOL., vol. 222, 1991, pages 581 | COLE ET AL.: "Monoclonal Antibodies and Cancer Therapy", 1985, ALAN R. LISS, pages: 77 | BOERNER ET AL., J. IMMUNOL., vol. 147, no. 1, 1991, pages 86 - 95 | FELLOUSE, F.A. ET AL., J. MOL. BIOL., vol. 373, no. 4, 2007, pages 924 - 40 | GUYER ET AL., J. IMMUNOL., vol. 117, 1976, pages 587 | KIM ET AL., J. IMMUNOL., vol. 24, 1994, pages 249 | HEIN J.: "Remington's Pharmaceutical Sciences", vol. 183, 1990, ACADEMIC PRESS, INC., article "Unified Approach to Alignment and Phylogenes", pages: 626 - 645 | "Remington, The Science and Practice of Pharmacy", 2005, MACK PUBLISHING | MAKABE ET AL., J. BIOL. CHEM., vol. 283, 2007, pages 1156 - 1166 | "GenBank", Database accession no. CR542051.1 | HIGGINS, D.G.SHARP, P.M., CABIOS, vol. 5, 1989, pages 151 - 153 | MYERS, E.W.MULLERW., CABIOS, vol. 4, 1988, pages 11 - 17 | ROBINSON, E.D., COMB. THEOR., vol. 11, 1971, pages 105 | SNEATH, P.H.A.SOKAL, R.R.: "Numerical Taxonomy the Principles and Practice of Numerical Taxonomy", 1973, FREEMAN PRESS | WILBUR, W.J.LIPMAN, D.J., PROC. NATL. ACAD. SCI. USA, vol. 80, 1983, pages 726 - 730 | "PCR: The Polymerase Chain Reaction", 1994, BIRKAUSWER PRESS | "GeneBank", Database accession no. AY358337.1 | ABDICHE ET AL., ANAL. BIOCHEM., vol. 411, 2011, pages 139 - 151 | MYSZKA, J. MOL. RECOGNIT., vol. 12, 1999, pages 279 - 284 |