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Extract from the Register of European Patents

EP About this file: EP4129330

EP4129330 - COMPOSITIONS AND METHODS FOR DENGUE VIRUS CHIMERIC CONSTRUCTS IN VACCINES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  12.07.2024
Database last updated on 09.04.2026
FormerThe patent has been granted
Status updated on  04.08.2023
FormerGrant of patent is intended
Status updated on  16.03.2023
FormerExamination is in progress
Status updated on  02.12.2022
Most recent event   Tooltip26.12.2025Lapse of the patent in a contracting state
New state(s): TR		published on 28.01.2026  [2026/05]
Applicant(s)For all designated states
Takeda Vaccines, Inc.
75 Sidney Street
Cambridge, MA 02139 / US
For all designated states
The Government of The United States of America as represented by The Secretary of The Department of Health and Human Services
4770 Buford Highway
Technology Transfer Office (K79)
Atlanta, GA 30341 / US
[2023/06]
Inventor(s)01 / STINCHCOMB, Dan T.
Fort Collins, 80528 / US
02 / KINNEY, Claire
Fort Collins, 80526 / US
03 / KINNEY, Richard M.
Fort Collins, 80526 / US
04 / LIVENGOOD, Jill A.
Cambridge, 02139 / US
 [2023/06]
Representative(s)Maiwald GmbH
Elisenhof
Elisenstraße 3
80335 München / DE
[2023/06]
Application number, filing date22182269.512.03.2014
[2023/06]
Priority number, dateUS201361800204P15.03.2013         Original published format: US 201361800204 P
[2023/06]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP4129330
Date:08.02.2023
Language:EN
[2023/06]
Type: B1 Patent specification 
No.:EP4129330
Date:06.09.2023
Language:EN
[2023/36]
Search report(s)(Supplementary) European search report - dispatched on:EP25.10.2022
ClassificationIPC:A61K39/12
[2023/06]
CPC:
A61K38/162 (EP,US); C07K14/005 (KR,US); A61K31/7048 (EP,US);
A61K31/713 (EP,US); A61K39/12 (EP,KR,US); A61P31/12 (EP);
A61P31/14 (EP,KR,US); A61P37/04 (EP); C07K14/1825 (US);
C07K19/00 (US); C12N15/09 (US); C12N15/8613 (US);
A61K2039/5254 (EP,US); A61K2039/70 (EP,US); C07K2319/00 (EP,US);
C12N2770/24122 (EP,KR,US); C12N2770/24134 (EP,KR,US); C12N2770/24141 (US);
C12N2770/24143 (EP,US); C12N2770/24161 (KR); C12N2770/24162 (EP,US);
Y02A50/30 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/17]
Former [2023/06]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
TitleGerman:ZUSAMMENSETZUNGEN UND VERFAHREN FÜR CHIMÄRE DENGUE-VIRUSKONSTRUKTE IN IMPFSTOFFEN[2023/06]
English:COMPOSITIONS AND METHODS FOR DENGUE VIRUS CHIMERIC CONSTRUCTS IN VACCINES[2023/06]
French:COMPOSITIONS ET PROCÉDÉS POUR CONSTRUCTIONS CHIMÉRIQUES DU VIRUS DE LA DENGUE DANS DES VACCINS[2023/06]
Examination procedure18.10.2022Examination requested  [2023/06]
25.10.2022Date on which the examining division has become responsible
30.11.2022Despatch of a communication from the examining division (Time limit: M04)
02.12.2022Reply to a communication from the examining division
16.02.2023Despatch of a communication from the examining division (Time limit: M01)
22.02.2023Reply to a communication from the examining division
17.03.2023Communication of intention to grant the patent
25.07.2023Fee for grant paid
25.07.2023Fee for publishing/printing paid
25.07.2023Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP14722014.9  / EP2968516
EP20154012.7  / EP3689374
Opposition(s)07.06.2024No opposition filed within time limit [2024/33]
Fees paidRenewal fee
30.06.2022Renewal fee patent year 03
30.06.2022Renewal fee patent year 04
30.06.2022Renewal fee patent year 05
30.06.2022Renewal fee patent year 06
30.06.2022Renewal fee patent year 07
30.06.2022Renewal fee patent year 08
30.06.2022Renewal fee patent year 09
22.03.2023Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCY12.03.2014
HU12.03.2014
AT06.09.2023
BG06.09.2023
CZ06.09.2023
FI06.09.2023
MC06.09.2023
NL06.09.2023
PL06.09.2023
RS06.09.2023
SE06.09.2023
SM06.09.2023
TR06.09.2023
NO06.12.2023
PT08.01.2024
IE12.03.2024
BE31.03.2024
CH31.03.2024
[2026/05]
Former [2025/41]CY12.03.2014
HU12.03.2014
AT06.09.2023
BG06.09.2023
CZ06.09.2023
FI06.09.2023
MC06.09.2023
NL06.09.2023
PL06.09.2023
RS06.09.2023
SE06.09.2023
SM06.09.2023
NO06.12.2023
PT08.01.2024
IE12.03.2024
BE31.03.2024
CH31.03.2024
Former [2025/37]CY12.03.2014
AT06.09.2023
BG06.09.2023
CZ06.09.2023
FI06.09.2023
MC06.09.2023
NL06.09.2023
PL06.09.2023
RS06.09.2023
SE06.09.2023
SM06.09.2023
NO06.12.2023
PT08.01.2024
IE12.03.2024
BE31.03.2024
CH31.03.2024
Former [2025/11]AT06.09.2023
BG06.09.2023
CZ06.09.2023
FI06.09.2023
MC06.09.2023
NL06.09.2023
PL06.09.2023
RS06.09.2023
SE06.09.2023
SM06.09.2023
NO06.12.2023
PT08.01.2024
IE12.03.2024
BE31.03.2024
CH31.03.2024
Former [2025/08]AT06.09.2023
BG06.09.2023
CZ06.09.2023
FI06.09.2023
MC06.09.2023
NL06.09.2023
PL06.09.2023
RS06.09.2023
SE06.09.2023
SM06.09.2023
NO06.12.2023
PT08.01.2024
BE31.03.2024
Former [2024/52]AT06.09.2023
BG06.09.2023
CZ06.09.2023
FI06.09.2023
MC06.09.2023
NL06.09.2023
PL06.09.2023
RS06.09.2023
SE06.09.2023
SM06.09.2023
NO06.12.2023
PT08.01.2024
Former [2024/51]AT06.09.2023
BG06.09.2023
CZ06.09.2023
FI06.09.2023
NL06.09.2023
PL06.09.2023
RS06.09.2023
SE06.09.2023
SM06.09.2023
NO06.12.2023
PT08.01.2024
Former [2024/27]AT06.09.2023
CZ06.09.2023
FI06.09.2023
NL06.09.2023
PL06.09.2023
RS06.09.2023
SE06.09.2023
SM06.09.2023
NO06.12.2023
PT08.01.2024
Former [2024/23]AT06.09.2023
CZ06.09.2023
FI06.09.2023
NL06.09.2023
RS06.09.2023
SE06.09.2023
SM06.09.2023
NO06.12.2023
PT08.01.2024
Former [2024/20]FI06.09.2023
NL06.09.2023
RS06.09.2023
SE06.09.2023
SM06.09.2023
NO06.12.2023
Former [2024/14]FI06.09.2023
NL06.09.2023
RS06.09.2023
SE06.09.2023
NO06.12.2023
Former [2024/10]FI06.09.2023
RS06.09.2023
SE06.09.2023
NO06.12.2023
Former [2024/09]FI06.09.2023
SE06.09.2023
NO06.12.2023
Former [2024/08]NO06.12.2023
Documents cited:Search[E] WO2014074912  (INVIRAGEN INC et al.)
 [E] WO2014093182  (INVIRAGEN INC et al.)
 [A] WO0160847  (US HEALTH et al.)
 [XP]   CLAIRE Y.-H. HUANG ET AL: "Genetic and Phenotypic Characterization of Manufacturing Seeds for a Tetravalent Dengue Vaccine (DENVax)", PLOS NEGLECTED TROPICAL DISEASES, vol. 7, no. 5, 30 May 2013 (2013-05-30), pages e2243, XP055130810, ISSN: 1935-2727, DOI: 10.1371/journal.pntd.0002243

DOI:   http://dx.doi.org/10.1371/journal.pntd.0002243
 [Y]   JORGE E OSORIO ET AL: "Development of DENVax: A chimeric dengue-2 PDK-53-based tetravalent vaccine for protection against dengue fever", VACCINE, vol. 29, no. 42, 21 July 2011 (2011-07-21), pages 7251 - 7260, XP028285284, ISSN: 0264-410X, [retrieved on 20110711], DOI: 10.1016/J.VACCINE.2011.07.020 [Y] 18-24,37-51 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.vaccine.2011.07.020
 [XP]   HUANG C Y-H ET AL: "Dengue 2 PDK-53 virus as a chimeric carrier for tetravalent dengue vaccine development", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 77, no. 21, 1 November 2003 (2003-11-01), pages 11436 - 11447, XP003005064, ISSN: 0022-538X, DOI: 10.1128/JVI.77.21.11436-11447.2003 [XP] 1-30 * the whole document *

DOI:   http://dx.doi.org/10.1128/JVI.77.21.11436-11447.2003
 [E]   BUTRAPET S ET AL: "Attenuation markers of a candidate dengue type 2 vaccine virus, strain 16681 (PDK-53), are defined by mutations in the 5' noncoding region and nonstructural proteins 1 and 3", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 74, no. 7, 1 April 2000 (2000-04-01), pages 3011 - 3019, XP002174038, ISSN: 0022-538X, DOI: 10.1128/JVI.74.7.3011-3019.2000

DOI:   http://dx.doi.org/10.1128/JVI.74.7.3011-3019.2000
 [E]   HSIANG-CHI LEE ET AL: "Dengue Type 4 Live-Attenuated Vaccine Viruses Passaged in Vero Cells Affect Genetic Stability and Dengue-Induced Hemorrhaging in Mice", PLOS ONE, vol. 6, no. 10, 28 October 2011 (2011-10-28), pages e25800, XP055148033, DOI: 10.1371/journal.pone.0025800

DOI:   http://dx.doi.org/10.1371/journal.pone.0025800
by applicantUS1961800204
   SAMBROOKFRITSCHMANIATIS: "Molecular Cloning: A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
   "Animal Cell Culture", 1986
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.