blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

Latvia joins the Federated Register
Click here for more information on the Federated Register.

2025-04-16

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP2970493

EP2970493 - METHODS FOR ACHIEVING THERAPEUTICALLY EFFECTIVE DOSES OF ANTI-CD47 AGENTS [Right-click to bookmark this link]
StatusThe patent has been granted
Status updated on  01.03.2019
Database last updated on 26.04.2025
FormerGrant of patent is intended
Status updated on  11.10.2018
FormerExamination is in progress
Status updated on  11.08.2017
Most recent event   Tooltip29.11.2024New entry: Date of oral proceedings 
Applicant(s)For all designated states
The Board of Trustees of the Leland Stanford Junior University
Office of the General Counsel
Building 170, Third Floor, Main Quad
P.O. Box 20386
Stanford, CA 94305-2038 / US
[2019/38]
Former [2016/03]For all designated states
The Board of Trustees of the Leland Stanford Junior University
Office of the General Counsel
Building 170, 3rd Floor, Main Quad
P.O. Box 20386
Stanford, CA 94305-2038 / US
Inventor(s)01 / WILLINGHAM, Stephen
265 Campus Drive
Stanford, California 94305 / US
02 / HOWARD, Maureen
Stanford University The Institute for Stem Cell Biology and
Regenerative Medicine
265 Campus Drive, 3rd Floor
Stanford, CA 94305 / US
03 / LIU, Jie
3119 Stockton Place
Palo Alto, CA 94303 / US
04 / MAJETI, Ravindra
Stanford Institute for Stem Cell Bio and
Regenerative Medicine
1050 Arastradero Road
Building A
Stanford, California 94304 / US
05 / PROHASKA, Susan Sweeney
725 Mariposa Avenue No 207
Mountain View, CA 94041 / US
06 / VOLKMER, Anne K.
265 Campus Drive
Stanford, CA 94305 / US
07 / VOLKMER, Jens-Peter
265 Campus Drive
Stanford, CA 94305 / US
08 / WEISSMAN, Irving L.
747 Santa Ynez Street
Stanford, CA 94305 / US
 [2016/11]
Former [2016/08]01 / WILLINGHAM, Stephen
265 Campus Drive
Stanford, California 94305 / US
02 / HOWARD, Maureen
Stanford University The Institute for Stem Cell Biology and
Regenerative Medicine
265 Campus Drive, 3rd Floor
Stanford, CA 94305 / US
03 / LIU, Jie
3119 Stockton Place
Palo Alto, CA 94303 / US
04 / MAJETI, Ravindra
Stanford Institute for Stem Cell Bio and
Regenerative Medicine
1050 Arastradero Road
Building A
Stanford, California 94304 / US
05 / PROHASKA, Susan
725 Mariposa Avenue No 207
Mountain View, CA 94041 / US
06 / VOLKMER, Anne K.
265 Campus Drive
Stanford, CA 94305 / US
07 / VOLKMER, Jens-Peter
265 Campus Drive
Stanford, CA 94305 / US
08 / WEISSMAN, Irving L.
747 Santa Ynez Street
Stanford, CA 94305 / US
Former [2016/03]01 / WILLINGHAM, Stephen
265 Campus Drive
Stanford, California 94305 / US
02 / HOWARD, Maureen
/ US
03 / LIU, Jie
3119 Stockton Place
Palo Alto, CA 94303 / US
04 / MAJETI, Ravindra
Stanford Institute for Stem Cell Bio and
Regenerative Medicine
1050 Arastradero Road
Building A
Stanford, California 94304 / US
05 / PROHASKA, Susan
725 Mariposa Avenue No 207
Mountain View, CA 94041 / US
06 / VOLKMER, Anne K.
265 Campus Drive
Stanford, CA 94305 / US
07 / VOLKMER, Jens-Peter
265 Campus Drive
Stanford, CA 94305 / US
08 / WEISSMAN, Irving L.
747 Santa Ynez Street
Stanford, CA 94305 / US
Representative(s)Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [2016/03]Chapman, Desmond Mark
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
Application number, filing date14768797.426.02.2014
[2016/03]
WO2014US18743
Priority number, dateUS201361800102P15.03.2013         Original published format: US 201361800102 P
[2016/03]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014149477
Date:25.09.2014
Language:EN
[2014/39]
Type: A1 Application with search report 
No.:EP2970493
Date:20.01.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 25.09.2014 takes the place of the publication of the European patent application.
[2016/03]
Type: B1 Patent specification 
No.:EP2970493
Date:03.04.2019
Language:EN
[2019/14]
Search report(s)International search report - published on:US25.09.2014
(Supplementary) European search report - dispatched on:EP05.10.2016
ClassificationIPC:C07K16/28, A61K38/18
[2016/44]
CPC:
C07K16/2803 (EP,US); A61K38/1774 (EP,US); A61K38/1816 (EP,US);
A61K39/3955 (EP,US); A61P31/00 (EP); A61P35/00 (EP);
A61P35/02 (EP); A61P43/00 (EP); C07K16/2896 (EP,US);
A61K2039/505 (EP,US); A61K2039/54 (EP,US); A61K2039/545 (EP,US);
C07K2317/24 (EP,US); C07K2317/33 (EP,US); C07K2317/73 (EP,US);
C07K2317/76 (EP,US); C07K2317/92 (EP,US); C07K2319/30 (EP,US);
Y02A50/30 (EP,US) (-)
C-Set:
A61K39/3955, A61K2300/00 (EP)
Former IPC [2016/03]C07K16/28
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/03]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:VERFAHREN ZUR ERZIELUNG THERAPEUTISCH WIRKSAMER DOSIERUNGEN VON ANTI-CD47-MITTELN[2016/03]
English:METHODS FOR ACHIEVING THERAPEUTICALLY EFFECTIVE DOSES OF ANTI-CD47 AGENTS[2016/03]
French:PROCÉDÉS D'OBTENTION DE DOSES THÉRAPEUTIQUEMENT EFFICACES D'AGENTS ANTI-CD47[2016/03]
Entry into regional phase03.09.2015National basic fee paid 
03.09.2015Search fee paid 
03.09.2015Designation fee(s) paid 
03.09.2015Examination fee paid 
Examination procedure03.09.2015Examination requested  [2016/03]
28.04.2017Amendment by applicant (claims and/or description)
11.08.2017Despatch of a communication from the examining division (Time limit: M04)
20.12.2017Reply to a communication from the examining division
14.03.2018Despatch of a communication from the examining division (Time limit: M02)
24.05.2018Reply to a communication from the examining division
12.10.2018Communication of intention to grant the patent
22.02.2019Fee for grant paid
22.02.2019Fee for publishing/printing paid
22.02.2019Receipt of the translation of the claim(s)
Divisional application(s)EP19166334.3  / EP3536709
EP20201319.9  / EP3792285
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  11.08.2017
Opposition(s)Opponent(s)01  02.01.2020  07.01.2020  ADMISSIBLE
König Szynka Tilmann von Renesse
Patentanwälte Partnerschaft mbB
Mönchenwerther Strasse 11
40545 Düsseldorf / DE
Opponent's representative
König Szynka Tilmann von Renesse Patentanwälte Partnerschaft mbB Düsseldorf, et al, et al
Mönchenwerther Straße 11
40545 Düsseldorf / DE
 02  03.01.2020  07.01.2020  ADMISSIBLE
Genmab A/S
Kalvebod Brygge 43
1560 Copenhagen V / DK
Opponent's representative
J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
 [2023/42]
Former [2022/30]
Opponent(s)01  02.01.2020  07.01.2020  ADMISSIBLE
König Szynka Tilmann von Renesse
Patentanwälte Partnerschaft mbB
Mönchenwerther Strasse 11
40545 Düsseldorf / DE
Opponent's representative
König Szynka Tilmann von Renesse Patentanwälte Partnerschaft mbB Düsseldorf, et al, et al
Mönchenwerter Straße 11
40545 Düsseldorf / DE
 02  03.01.2020  07.01.2020  ADMISSIBLE
Genmab A/S
Kalvebod Brygge 43
1560 Copenhagen V / DK
Opponent's representative
J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
Former [2020/07]
Opponent(s)01  02.01.2020  07.01.2020  ADMISSIBLE
König Szynka Tilmann von Renesse
Patentanwälte Partnerschaft mbB
Mönchenwerther Strasse 11
40545 Düsseldorf / DE
Opponent's representative
König, Gregor Sebastian, et al, et al
König-Szynka-Tilmann-von Renesse
Patentanwälte Partnerschaft mbB
Mönchenwerther Straße 11
40545 Düsseldorf / DE
 02  03.01.2020  07.01.2020  ADMISSIBLE
Genmab A/S
Kalvebod Brygge 43
1560 Copenhagen V / DK
Opponent's representative
J A Kemp LLP
14 South Square
Gray's Inn
London WC1R 5JJ / GB
20.01.2020Invitation to proprietor to file observations on the notice of opposition
02.06.2020Reply of patent proprietor to notice(s) of opposition
18.10.2021Cancellation of oral proceeding that was planned for 21.10.2021
21.10.2021Date of oral proceedings
02.12.2021Date of oral proceedings
13.01.2022Despatch of minutes of oral proceedings
13.01.2022Despatch of communication that the patent will be revoked
11.09.2025Date of oral proceedings
Appeal following opposition28.01.2022Appeal received No.  T0235/22
28.01.2022Payment of appeal fee
23.05.2022Statement of grounds filed
06.06.2024Result of appeal procedure: continuation of opposition procedure
15.07.2024Despatch of the decision of the Board of Appeal
Fees paidRenewal fee
10.02.2016Renewal fee patent year 03
10.02.2017Renewal fee patent year 04
14.02.2018Renewal fee patent year 05
13.02.2019Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU26.02.2014
AL03.04.2019
CY03.04.2019
CZ03.04.2019
EE03.04.2019
HR03.04.2019
LT03.04.2019
LV03.04.2019
MK03.04.2019
MT03.04.2019
PL03.04.2019
RO03.04.2019
RS03.04.2019
SI03.04.2019
SK03.04.2019
SM03.04.2019
TR03.04.2019
BG03.07.2019
GR04.07.2019
[2022/32]
Former [2022/28]HU26.02.2014
AL03.04.2019
CY03.04.2019
CZ03.04.2019
EE03.04.2019
HR03.04.2019
LT03.04.2019
LV03.04.2019
MT03.04.2019
PL03.04.2019
RO03.04.2019
RS03.04.2019
SI03.04.2019
SK03.04.2019
SM03.04.2019
TR03.04.2019
BG03.07.2019
GR04.07.2019
Former [2020/26]AL03.04.2019
CZ03.04.2019
EE03.04.2019
HR03.04.2019
LT03.04.2019
LV03.04.2019
PL03.04.2019
RO03.04.2019
RS03.04.2019
SI03.04.2019
SK03.04.2019
SM03.04.2019
TR03.04.2019
BG03.07.2019
GR04.07.2019
Former [2020/17]AL03.04.2019
CZ03.04.2019
EE03.04.2019
HR03.04.2019
LT03.04.2019
LV03.04.2019
PL03.04.2019
RO03.04.2019
RS03.04.2019
SK03.04.2019
SM03.04.2019
TR03.04.2019
BG03.07.2019
GR04.07.2019
Former [2020/14]AL03.04.2019
CZ03.04.2019
EE03.04.2019
HR03.04.2019
LT03.04.2019
LV03.04.2019
PL03.04.2019
RO03.04.2019
RS03.04.2019
SK03.04.2019
SM03.04.2019
BG03.07.2019
GR04.07.2019
Former [2020/11]AL03.04.2019
CZ03.04.2019
EE03.04.2019
HR03.04.2019
LT03.04.2019
LV03.04.2019
PL03.04.2019
RO03.04.2019
RS03.04.2019
SK03.04.2019
BG03.07.2019
GR04.07.2019
Former [2020/10]AL03.04.2019
CZ03.04.2019
HR03.04.2019
LT03.04.2019
LV03.04.2019
PL03.04.2019
RO03.04.2019
RS03.04.2019
BG03.07.2019
GR04.07.2019
Former [2019/52]AL03.04.2019
CZ03.04.2019
HR03.04.2019
LT03.04.2019
LV03.04.2019
PL03.04.2019
RS03.04.2019
BG03.07.2019
GR04.07.2019
Former [2019/51]AL03.04.2019
CZ03.04.2019
HR03.04.2019
LT03.04.2019
LV03.04.2019
RS03.04.2019
BG03.07.2019
GR04.07.2019
Former [2019/50]AL03.04.2019
CZ03.04.2019
HR03.04.2019
LT03.04.2019
LV03.04.2019
RS03.04.2019
GR04.07.2019
Former [2019/49]AL03.04.2019
CZ03.04.2019
HR03.04.2019
LT03.04.2019
Former [2019/47]LT03.04.2019
Documents cited:SearchUS2014140989  [ ] (ECKELMAN BRENDAN [US], et al);
International search[A]US2007113297  (YANG YONGGUANG [US], et al);
 [Y]US2010239578  (DANSKA JAYNE [CA], et al);
 [Y]US2010323949  (LUE AIFENG [CN], et al);
 [Y]WO2011143624  (UNIV LELAND STANFORD JUNIOR [US], et al);
 [X]US2012282174  (WEISSMAN IRVING L [US], et al);
 [XP]WO2013109752  (UNIV LELAND STANFORD JUNIOR [US]);
by applicantUS2010239579
 US2011014119
 WO2011143624
 US2012282174
 WO2013109752
OppositionWO2011143624
 WO2014108483
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.