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Extract from the Register of European Patents

EP About this file: EP2992098

EP2992098 - COMPOSITIONS AND METHODS FOR MODULATING HBV AND TTR EXPRESSION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  07.02.2020
Database last updated on 26.04.2025
FormerThe patent has been granted
Status updated on  22.02.2019
FormerGrant of patent is intended
Status updated on  18.02.2019
FormerExamination is in progress
Status updated on  29.01.2019
FormerGrant of patent is intended
Status updated on  20.09.2018
FormerExamination is in progress
Status updated on  03.11.2017
Most recent event   Tooltip07.02.2020No opposition filed within time limitpublished on 11.03.2020  [2020/11]
Applicant(s)For all designated states
Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010 / US
[2016/10]
Inventor(s)01 / PRAKASH, Thazha, P.
2855 Gazelle Court
Carlsbad, CA 92010 / US
02 / SETH, Punit, P.
2855 Gazelle Court
Carlsbad, CA 92010 / US
03 / SWAYZE, Eric, E.
2855 Gazelle Court
Carlsbad, CA 92010 / US
 [2016/10]
Representative(s)Learoyd, Stephanie Anne
GlaxoSmithKline
Global Patents (CN925.1)
980 Great West Road
Brentford, Middlesex TW8 9GS / GB
[N/P]
Former [2016/10]Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
Application number, filing date14791344.601.05.2014
[2016/10]
WO2014US36463
Priority number, dateUS201361818442P01.05.2013         Original published format: US 201361818442 P
US201361823826P15.05.2013         Original published format: US 201361823826 P
US201361843887P08.07.2013         Original published format: US 201361843887 P
US201361871673P29.08.2013         Original published format: US 201361871673 P
US201361880790P20.09.2013         Original published format: US 201361880790 P
US201461976991P08.04.2014         Original published format: US 201461976991 P
US201461986867P30.04.2014         Original published format: US 201461986867 P
[2016/10]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2014179627
Date:06.11.2014
Language:EN
[2014/45]
Type: A2 Application without search report 
No.:EP2992098
Date:09.03.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 06.11.2014 takes the place of the publication of the European patent application.
[2016/10]
Type: B1 Patent specification 
No.:EP2992098
Date:27.03.2019
Language:EN
[2019/13]
Search report(s)International search report - published on:US16.04.2015
(Supplementary) European search report - dispatched on:EP08.12.2016
ClassificationIPC:C12N15/113, A61P31/20, A61K31/7088, A61K31/713
[2017/02]
CPC:
A61K47/549 (EP,IL,RU,US); C12N15/113 (EP,EA,IL,KR,RU,US); A61K31/7125 (IL,RU);
A61K31/7088 (IL,MA,RU,US); A61K31/7105 (IL); A61K31/713 (IL,MA,RU,US);
A61K47/59 (EP,IL); A61K48/00 (IL); A61P25/00 (EP,IL);
A61P43/00 (EP,IL); C07H21/00 (IL,RU); C07H21/04 (IL,RU,US);
C12N15/111 (IL,RU,US); C12N15/1137 (IL); C12Y301/03048 (EP,IL);
C12N2310/11 (EP,IL,KR,US); C12N2310/113 (IL,US); C12N2310/14 (KR);
C12N2310/17 (IL,US); C12N2310/31 (IL,US); C12N2310/315 (EP,IL,KR,US);
C12N2310/32 (IL); C12N2310/321 (IL,US); C12N2310/322 (IL,US);
C12N2310/3231 (EP,IL,US); C12N2310/3341 (EP,IL,US); C12N2310/34 (IL);
C12N2310/341 (EP,IL,US); C12N2310/346 (EP,IL,US); C12N2310/35 (IL);
C12N2310/351 (EP,IL,KR,US); C12N2310/3511 (IL,US); C12N2310/3513 (IL,US);
C12N2310/3515 (IL,US); C12N2310/3525 (IL,KR,US); C12N2310/353 (IL,US);
C12N2320/32 (EP,IL,US) (-)
C-Set:
C12N2310/321, C12N2310/3525 (US,EP);
C12N2310/322, C12N2310/3525 (US)
Former IPC [2016/10]C12N15/113
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/10]
Extension statesBA27.11.2015
ME27.11.2015
TitleGerman:ZUSAMMENSETZUNGEN UND VERFAHREN ZUR MODULIERUNG DER HBV- UND TTR-EXPRESSION[2016/10]
English:COMPOSITIONS AND METHODS FOR MODULATING HBV AND TTR EXPRESSION[2016/10]
French:COMPOSITIONS ET MÉTHODES POUR MODULER L'EXPRESSION DE HBV ET DE TTR[2016/10]
Entry into regional phase27.11.2015National basic fee paid 
27.11.2015Search fee paid 
27.11.2015Designation fee(s) paid 
27.11.2015Examination fee paid 
Examination procedure27.11.2015Examination requested  [2016/10]
13.07.2017Amendment by applicant (claims and/or description)
02.11.2017Despatch of a communication from the examining division (Time limit: M06)
11.05.2018Reply to a communication from the examining division
21.09.2018Communication of intention to grant the patent
29.01.2019Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
29.01.2019Fee for grant paid
29.01.2019Fee for publishing/printing paid
18.02.2019Information about intention to grant a patent
18.02.2019Receipt of the translation of the claim(s)
Divisional application(s)EP19164959.9  / EP3524680
EP19208621.3   Application refused  : 05.07.2020
EP20205948.1  / EP3828275
EP25155370.7
Opposition(s)03.01.2020No opposition filed within time limit [2020/11]
Fees paidRenewal fee
10.05.2016Renewal fee patent year 03
10.05.2017Renewal fee patent year 04
11.05.2018Renewal fee patent year 05
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]WO2009073809  (ALNYLAM PHARMACEUTICALS INC [US], et al);
 [AD]WO2012037254  (ALNYLAM PHARMACEUTICALS INC [US], et al);
 [A]US2013035366  (SWAYZE ERIC E [US], et al);
 [A]WO2013033230  (ISIS PHARMACEUTICALS INC [US], et al)
International search[Y]WO2009073809  (ALNYLAM PHARMACEUTICALS INC [US], et al);
 [X]WO2011139917  (ISIS PHARMACEUTICALS INC [US], et al);
 [A]US2012225927  (SAH DINAH WEN-YEE [US], et al);
 [A]US2013035366  (SWAYZE ERIC E [US], et al);
by applicantUS12129154
 US60989574
 US61026995
 US61026998
 US61056564
 US61086231
 US61097787
 US61099844
 US3687808
 US4751219
 US4845205
 US5034506
 US5130302
 US5134066
 US5166315
 US5175273
 US5185444
 WO9414226
 US5367066
 US5432272
 US5457187
 US5459255
 US5484908
 US5502177
 US5525711
 US5552540
 US5587469
 US5594121
 US5596091
 US5614617
 WO9720563
 US5645985
 US5681941
 WO9746098
 US5698685
 WO9813381
 US5750692
 US5763588
 US5830653
 US5994517
 US6005096
 US6268490
 US6300319
 US6383812
 WO0243771
 US6525191
 US6525031
 US2003077829
 US2003119724
 US6620916
 US6660720
 US6670461
 WO2004024757
 US6770748
 US2004171570
 US6794499
 WO2004101619
 WO2004106356
 WO2005021570
 US6906182
 US2005130923
 US6908903
 US2005164235
 US7034133
 US7053207
 US2006148740
 US2006183886
 WO2007090071
 US7262177
 WO2007134181
 US2007287831
 US2008039618
 US2008108801
 US7399845
 WO2008101157
 WO2008098788
 US2008206869
 US7427672
 US2008281044
 US2008281041
 WO2008150729
 WO2008154401
 WO2009006478
 US7491805
 WO2009082607
 US7569686
 US2009203135
 US2009203132
 US7582744
 WO2009126933
 WO2009134487
 US2009286973
 WO2009143369
 WO2010036698
 WO2010054406
 US7723509
 WO2010077578
 WO2010088537
 US2010240730
 WO2010129709
 US7851615
 WO2010144740
 WO2010148013
 WO2011038356
 WO2011047312
 US2011097264
 US2011097265
 US2011123520
 WO2011100131
 US2011207799
 WO2011115818
 WO2011120053
 US2011269814
 WO2011163121
 US8106022
 US2012035115
 US8137695
 WO2012037254
 US8158601
 US2012095075
 US2012101148
 WO2012068187
 US2012128760
 US2012136042
 WO2012083185
 WO2012083046
 US2012157509
 US2012165393
 WO2012089352
 WO2012089602
 US2012230938
 WO2012145674
 WO2012145697
 US8313772
 WO2012177947
 US8344125
 US2013004427
 US8349308
 WO2013033230
 US8404862
 US2013109817
 US8435491
 US2013121954
 WO2013075035
 US8450467
 US2013178512
 US8501930
 US2013236968
 US8541548
 US8552163
 WO2013166121
 WO2013165816
 WO2008US64591
 WO2008US66154
 WO2008US68922
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.